The probiotic supplements industry focuses on products intended to enhance gut health through the introduction of beneficial bacteria. This growing sector features a variety of companies ranging from established giants to innovative startups. They offer a range of products like capsules, powders, and beverages tailored to diverse consumer needs, including digestive health and immunity. The industry is trending towards natural ingredients and personalized approaches for gut health, driven by increasing consumer awareness of probiotic benefits. Notable trends include a surge in plant-based formulations and an expanding market for pediatric and women's health probiotics.

This list features 24 companies varying in size from small teams to sizable enterprises. Headquartered in several regions, including the USA and the UK, these companies were founded between 1965 and 2020. They specialize in creating a range of probiotic supplements, offering products tailored for specific health needs or general wellness. Each company maintains a commitment to quality and innovation, while also engaging in research and development to enhance their offerings. This selection includes family-owned businesses and corporate entities, showcasing the industry’s versatility.

Read on to discover the top probiotic supplements companies.

Top 24 Probiotic Supplements Companies

1. Garden of Life

• Website: gardenoflife.com
• Ownership type: Corporate
• Headquarters: Palm Beach Gardens, Florida, United States (USA)
• Employee distribution: United States (USA) 90%, Other 10%
• Latest funding: March 2024
• Founded year: 2000
• Headcount: 201-500
• LinkedIn: garden-of-life

Garden of Life, founded in 2000 and based in Palm Beach Gardens, Florida, is a health supplement retailer that specializes in vitamins and dietary supplements. The company offers a wide array of products, prominently featuring probiotics, protein powders, and herbal supplements. Their focus is on providing clean, organic, and non-GMO products aimed at health-conscious consumers. Garden of Life has established a reputation for quality, with many of their probiotic products containing billions of clinically studied strains designed to promote digestive balance and immune health. The company is also certified as a B Corporation, reflecting its commitment to social and environmental performance. With a workforce of over 500 employees, Garden of Life continues to play a significant role in the health supplement industry, particularly in the probiotic segment.

2. RenewLife

• Website: renewlife.com
• Ownership type: Corporate
• Headquarters: Palm Harbor, Florida, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: May 2016
• Founded year: 1997
• Headcount: 51-200
• LinkedIn: renew-life

RenewLife, based in Palm Harbor, Florida, is a health supplement retailer that specializes in dietary supplements, with a notable focus on probiotics. Founded in 1997, the company has carved out a niche in the wellness industry, catering to health-conscious consumers looking to enhance their gut health and overall well-being. RenewLife operates an online store, providing direct access to a variety of products, including probiotics tailored for different age groups and health needs. Their product offerings include capsules, gummies, and powders, reflecting a commitment to accessibility and consumer preferences. The company also emphasizes quality, with a focus on clinically studied probiotic strains and guaranteed potency, which positions them as a credible option in the competitive probiotic market.

3. Jarrow Formulas

• Website: jarrow.com
• Ownership type: Private Equity
• Headquarters: Los Angeles, California, United States (USA)
• Latest funding: September 2020
• Founded year: 1977
• Headcount: 201-500
• LinkedIn: jarrow-formulas

Jarrow Formulas, based in Los Angeles, California, is a private equity-owned dietary supplement manufacturer that has been operational since 1977. The company specializes in a wide array of health products, prominently featuring probiotics, vitamins, and minerals. Jarrow Formulas is dedicated to serving health-conscious consumers who aim to enhance their wellness through scientifically formulated supplements. Their product offerings include notable probiotics like Jarro-Dophilus EPS and Fem-Dophilus, which are designed to support digestive health and women's health, respectively. The company places a strong emphasis on quality and efficacy, ensuring that their products meet rigorous standards for purity and potency. Jarrow Formulas collaborates with researchers and institutions to develop innovative formulations, reflecting their commitment to scientific integrity and consumer health. They have built a loyal customer base over the decades, which speaks to their reliability and relevance in the dietary supplement industry.

4. Optibac

• Website: optibacprobiotics.com
• Ownership type: Private
• Headquarters: Andover, England, United Kingdom (UK)
• Employee distribution: United Kingdom (UK) 83%, Ireland 12%, Vietnam 5%
• Founded year: 2004
• Headcount: 51-200
• LinkedIn: optibac-probiotics

Optibac Probiotics is a health and wellness company based in Andover, England, specializing in probiotic supplements. Established in 2004, Optibac has carved out a niche in the market by offering a range of products designed to enhance digestive health and overall well-being for consumers of all ages. The company prides itself on its scientific approach, utilizing well-researched probiotic strains in its formulations. Their product line includes options for everyday use, as well as specialized supplements for women, children, and specific health concerns. Optibac operates an online store, allowing direct consumer access to their products. They also emphasize sustainability, using eco-friendly packaging and supporting charitable initiatives. With a workforce of around 84 employees, Optibac has maintained a strong presence in the UK and Ireland, where they are recognized as a trusted brand in the probiotic sector.

5. Microbiome Labs

• Website: microbiomelabs.com
• Ownership type: Corporate
• Headquarters: Glenview, Illinois, United States (USA)
• Employee distribution: United States (USA) 94%, India 3%, Canada 3%
• Latest funding: $128.0M, December 2020
• Founded year: 2014
• Headcount: 51-200
• LinkedIn: megasporebiotic

Microbiome Labs, based in Glenview, Illinois, is a health supplement company that specializes in probiotics and microbiome health products. Founded in 2014, the company has made a name for itself by offering scientifically-backed supplements aimed at improving gut health, cognitive function, and overall wellness. Their product line includes a variety of formulations targeting gastrointestinal, cognitive, metabolic, immune, skin, and even pet health. Microbiome Labs emphasizes education and research, having participated in over 300 conferences and completed 14 clinical trials to support their offerings. They cater to both healthcare practitioners and consumers, providing tools and resources to enhance health outcomes. The company has also secured significant funding, amounting to $128 million in December 2020, which underscores its growth potential and relevance in the health supplement industry.

6. Nature's Way

• Website: naturesway.com
• Ownership type: Private
• Headquarters: Green Bay, Wisconsin, United States (USA)
• Employee distribution: United States (USA) 88%, Canada 4%, Kenya 2%, Other 7%
• Founded year: 1968
• Headcount: 501-1000
• LinkedIn: schwabe_north_america

Nature's Way, founded in 1968 and based in Green Bay, Wisconsin, is a private health supplement retailer specializing in vitamins and dietary supplements. With a workforce of approximately 839 employees, the company has established itself as a significant player in the wellness market. Nature's Way offers a wide array of products aimed at supporting health, including herbal supplements and probiotics. Their probiotic range includes well-known brands like Fortify and Pearls, which are designed to promote digestive health and overall well-being. The company primarily operates through an online store, providing health-conscious consumers with direct access to their products. Nature's Way is committed to quality and transparency, ensuring that their offerings meet consumer expectations for efficacy and safety.

7. ProThera, Inc.

• Website: klaire.com
• Ownership type: Private
• Headquarters: Reno, Nevada, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2001
• Headcount: 51-200
• LinkedIn: prothera-inc-

ProThera, Inc., operating as SFI Health, is a health supplement manufacturer based in Reno, Nevada. Founded in 2001, the company has carved out a niche in the dietary supplement market, with a strong emphasis on probiotics. Their product offerings are designed to support various aspects of health, including immune function and cognitive well-being. ProThera's commitment to quality is reflected in their use of clinically researched ingredients, which appeals to both healthcare practitioners and consumers. The company primarily sells its products online, ensuring direct access to their formulations. ProThera's probiotic line includes several products that target gut health, showcasing their dedication to addressing microbiome-related health issues.

8. Ancient Nutrition

• Website: ancientnutrition.com
• Ownership type: Corporate
• Headquarters: Franklin, Tennessee, United States (USA)
• Employee distribution: United States (USA) 97%, Canada 3%
• Latest funding: January 2025
• Founded year: 2016
• Headcount: 51-200
• LinkedIn: ancient-nutrition

Ancient Nutrition, founded in 2016 and based in Franklin, Tennessee, is a dietary supplement company that specializes in health products aimed at enhancing wellness. The company offers a variety of products, including collagen, protein powders, vitamins, and notably, probiotics. Their probiotic line is designed to support gut health and digestive function, appealing to a health-conscious demographic. Ancient Nutrition operates an online store, allowing customers to purchase products directly and subscribe for regular deliveries. The company emphasizes the use of clinically backed ingredients and ancient food preparation techniques, such as fermentation, to ensure the efficacy of their supplements. They are also committed to regenerative farming practices, which reflects their dedication to sustainability and health. With a workforce of around 147 employees, Ancient Nutrition is actively involved in the dietary supplement industry, focusing on innovative health solutions.

9. Symprove Ltd

• Website: symprove.com
• Ownership type: Corporate
• Headquarters: Farnham, England, United Kingdom (UK)
• Employee distribution: United Kingdom (UK) 94%, Czech Republic 3%, Slovakia 3%
• Latest funding: July 2020
• Founded year: 2002
• Headcount: 51-200
• LinkedIn: symprove

Symprove Ltd, founded in 2002 and based in Farnham, England, is a health supplement company that focuses on probiotic products designed to enhance gut health. With a workforce of 51-200 employees, Symprove has carved out a niche in the health supplement sector, particularly in the probiotic market. Their flagship product features a unique water-based formula that allows live bacteria to survive the digestive process, ensuring they reach the gut effectively. The company operates on a subscription model, offering both one-off purchases and ongoing delivery options, which caters to a growing consumer demand for convenience in health products. Symprove emphasizes scientific research and customer feedback, with a notable percentage of users reporting significant improvements in their digestive wellness. Their commitment to quality and customer satisfaction positions them as a relevant player in the probiotic supplements industry.

10. Enzymedica

• Website: enzymedica.com
• Ownership type: Venture Capital
• Headquarters: Venice, Florida, United States (USA)
• Employee distribution: United States (USA) 91%, United Arab Emirates 3%, Sweden 3%, Other 3%
• Latest funding: November 2013
• Founded year: 1998
• Headcount: 201-500
• LinkedIn: enzymedica

Enzymedica, founded in 1998 and based in Venice, Florida, is a health supplement retailer that focuses on digestive health. The company offers a wide array of products, including digestive enzymes and probiotics, aimed at improving digestion and overall wellness. Their online store model caters primarily to individuals seeking solutions for various digestive issues. Enzymedica emphasizes the quality of its ingredients, ensuring they are clean and scientifically validated. The company has built a reputation for its commitment to customer education and support, providing resources like a digestive health quiz to help consumers find the right products for their needs. With a workforce of around 99 employees, Enzymedica operates primarily in the United States, with a small presence in international markets. Their product offerings reflect a strong focus on digestive health, making them a notable player in the probiotic supplement industry.

11. New Chapter, Inc.

• Website: newchapter.com
• Ownership type: Private
• Headquarters: Brattleboro, Vermont, United States (USA)
• Employee distribution: United States (USA) 92%, Canada 8%
• Latest funding: August 2005
• Founded year: 1982
• Headcount: 201-500
• LinkedIn: new-chapter-inc-

New Chapter, Inc., founded in 1982 and based in Brattleboro, Vermont, specializes in health and wellness products, particularly natural vitamins and dietary supplements. The company operates primarily through an online store, providing direct access to a wide array of products aimed at supporting various wellness goals. New Chapter is known for its commitment to quality, utilizing whole-food ingredients and fermentation processes to enhance nutrient absorption. Their product line includes a dedicated section for probiotics, indicating their active involvement in this segment of the dietary supplement market. As a certified B Corporation, New Chapter emphasizes sustainability and ethical practices, further solidifying its position in the health and wellness industry.

12. Natren, Inc.

• Website: natren.com
• Ownership type: Family Owned
• Headquarters: Los Angeles, California, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1983
• Headcount: 51-200
• LinkedIn: natren-inc

Natren, Inc., based in Los Angeles, California, is a family-owned company that specializes in probiotic supplements aimed at enhancing digestive health. Since its inception in 1983, Natren has focused on developing a range of products that cater to various health concerns, appealing to consumers who prioritize their well-being. The company operates primarily through an online store, ensuring that customers have direct access to their offerings. Natren prides itself on its commitment to quality, as evidenced by its cGMP certification and a rigorous manufacturing process that includes third-party testing. The founder, Natasha Trenev, has played a pivotal role in introducing probiotics to the North American market, leveraging a rich cultural heritage in probiotic science. Natren's products are designed to support not only digestive health but also immune function and overall wellness, making them a significant player in the probiotic supplement industry.

13. Lallemand Solutions Santé - Usine PerfecLAB

• Website: lallemand-health-solutions.com
• Ownership type: Family Owned
• Headquarters: Quebec City, Quebec, Canada
• Founded year: 1994
• Headcount: 51-200
• LinkedIn: perfeclab

Lallemand Solutions Santé - Usine PerfecLAB, based in Quebec City, Canada, is a family-owned company founded in 1994. It operates as a manufacturer of probiotics, providing a variety of health solutions that target areas such as gut health, mental well-being, and women's health. The company serves both businesses in the health supplement industry and consumers looking for effective health solutions. Lallemand emphasizes research and development, ensuring that their probiotic formulations meet high-quality standards. They also offer contract development and manufacturing services, showcasing their expertise in creating custom probiotic blends. Their involvement in the Rosell Institute for Microbiome and Probiotics further highlights their commitment to advancing probiotic science and innovation.

14. Flora Health

• Website: florahealth.com
• Ownership type: Private
• Headquarters: Burnaby, British Columbia, Canada
• Employee distribution: Canada 69%, United States (USA) 31%
• Founded year: 1965
• Headcount: 51-200
• LinkedIn: flora-health

Flora Health, based in Burnaby, British Columbia, has been a player in the health supplement industry since its founding in 1965. The company specializes in natural health products, including vitamins, herbal remedies, and notably, probiotics. With a workforce of around 80 employees, Flora Health serves a health-conscious clientele seeking effective dietary supplements. Their product offerings include a variety of probiotics designed for different age groups and health needs, reflecting their commitment to enhancing wellness. Flora Health has helped over 100 million people with their health, showcasing their extensive reach and impact in the industry. The company operates primarily in Canada and the United States, catering to a growing demand for natural health solutions.

15. MaryRuth's

• Website: maryruthorganics.com
• Ownership type: Private
• Headquarters: Los Angeles, California, United States (USA)
• Employee distribution: United States (USA) 93%, Mexico 2%, Pakistan 2%, Other 2%
• Latest funding: August 2024
• Founded year: 2014
• Headcount: 51-200
• LinkedIn: maryruth-organics

MaryRuth's, founded in 2014 and based in Los Angeles, California, is a health supplement brand that specializes in a wide array of vitamins and dietary supplements tailored for various life stages. The company is dedicated to providing high-quality, vegan, and non-GMO products aimed at health-conscious consumers. Their product line includes liquid vitamins, gummies, and notably, probiotics, which are designed to support gut health and immune function. MaryRuth's emphasizes transparency and quality, as evidenced by their Clean Label Project certification, which ensures their products are tested for over 200 contaminants. This commitment to quality and safety positions them well within the health supplement industry, particularly in the probiotic segment.

16. ADM Deerland Probiotics & Enzymes

• Website: deerland.com
• Ownership type: Corporate
• Headquarters: Kennesaw, Georgia, United States (USA)
• Employee distribution: United States (USA) 86%, Denmark 12%, Ireland 2%
• Latest funding: November 2021
• Founded year: 1990
• Headcount: 201-500
• LinkedIn: deerland

ADM Deerland Probiotics & Enzymes, based in Kennesaw, Georgia, is a nutrition-focused company that has been operational since 1990. It specializes in human and animal nutrition, offering a wide array of products that include probiotics, prebiotics, and enzymes. The company serves a variety of clients, including food and beverage manufacturers and dietary supplement companies, who depend on ADM's innovative solutions to enhance health and wellness in their offerings. In 2021, ADM acquired Deerland, significantly bolstering its portfolio in microbiome solutions. This acquisition allows ADM to leverage Deerland's expertise in probiotic and dietary supplement technology, which includes 12 branded product lines. The company is committed to research and development, ensuring that its products are backed by clinical studies, thus meeting the growing consumer demand for effective health solutions.

17. Velbiom Probiotics

• Website: velbiom.com
• Ownership type: Venture Capital
• Headquarters: Bengaluru, Karnataka, India
• Employee distribution: India 100%
• Latest funding: Seed, August 2020
• Founded year: 2017
• Headcount: 51-200
• LinkedIn: tenshi-lifecare-pvt-ltd

Velbiom Probiotics, based in Bengaluru, Karnataka, India, is a health supplement company that specializes in probiotic products aimed at enhancing gut health and overall wellness. Established in 2017, Velbiom claims to be the first exclusive probiotic company in India, offering a wide range of strain-specific and site-specific products. Their product line caters to various demographics, including infants, children, adults, and the elderly, addressing common digestive issues and boosting immunity. The company operates primarily through an online store, facilitating direct access to their products for consumers. Velbiom is committed to raising awareness about probiotics and collaborates with medical practitioners and researchers to develop holistic formulations. Their focus on natural ingredients and clinically proven solutions positions them as a relevant player in the health supplement industry.

18. Nordic Naturals

• Website: nordicnaturals.com
• Ownership type: Family Owned
• Headquarters: Watsonville, California, United States (USA)
• Employee distribution: United States (USA) 89%, Peru 5%, Other 6%
• Founded year: 1995
• Headcount: 201-500
• LinkedIn: nordic-naturals

Nordic Naturals, founded in 1995 and based in Watsonville, California, is a family-owned health supplement company. The firm specializes in high-quality omega-3 oils, vitamins, and probiotics, catering to health-conscious consumers. Nordic Naturals emphasizes the purity and effectiveness of its products, which undergo extensive testing to meet stringent quality standards. The company has made significant strides in the health supplement industry, particularly with its Nordic Flora line, which includes various probiotic formulations. Their products are designed to support digestive health and overall wellness. Nordic Naturals has built partnerships with healthcare professionals and is recognized for its commitment to research-backed formulations. The company operates with a focus on sustainability, ensuring that its sourcing practices align with environmental standards.

19. Floré by Sun Genomics

• Website: flore.com
• Ownership type: Venture Capital
• Headquarters: San Diego, California, United States (USA)
• Employee distribution: United States (USA) 90%, France 10%
• Latest funding: Convertible note, November 2024
• Founded year: 2016
• Headcount: 11-50
• LinkedIn: sungenomics

Floré by Sun Genomics, founded in 2016 and based in San Diego, California, is a health supplement company that specializes in custom probiotics and gut health solutions. The firm offers a range of products tailored to individual microbiomes, including probiotics for adults, children, and infants, as well as gut microbiome testing. Floré operates primarily in the consumer health market, focusing on improving digestive health and overall well-being. The company prides itself on its scientific approach, utilizing advanced microbiome testing to create personalized probiotic formulations. Their products are manufactured in-house, ensuring quality control and direct oversight of the production process. Floré also emphasizes sustainability and social responsibility, contributing a portion of their proceeds to the Crohn’s & Colitis Foundation. This commitment to health and community engagement further solidifies their position in the probiotic industry.

20. SYNformulas GmbH

• Website: synformulas.com
• Ownership type: Private
• Headquarters: Flensburg, Schleswig-Holstein, Germany
• Employee distribution: Germany 95%, Italy 5%
• Founded year: 2011
• Headcount: 51-200
• LinkedIn: synformulas

SYNformulas GmbH, based in Flensburg, Schleswig-Holstein, Germany, specializes in probiotics and dietary supplements designed to enhance gut health. Established in 2011, the company operates under the Kijimea brand, offering a variety of innovative products that target digestive health and overall well-being. Their product line includes medical devices and dietary supplements, all developed based on scientific research in microbiome studies. The company prides itself on its collaboration with internationally recognized researchers and universities, ensuring that their offerings are grounded in evidence-based practices. With a workforce of around 38 employees, SYNformulas is dedicated to maintaining high quality and stability standards in its products, which are distributed across Europe. Their mission emphasizes a passion for gut health, aiming to unveil the potential of the microbiome to significantly improve patients' quality of life.

21. GoodBelly

• Website: goodbelly.com
• Ownership type: Venture Capital
• Headquarters: Boulder, Colorado, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: $12.0M, June 2018
• Founded year: 2006
• Headcount: 11-50
• LinkedIn: goodbelly-by-nextfoods

GoodBelly, a brand under NextFoods, Inc., was founded in 2006 and is based in Boulder, Colorado. The company focuses on creating probiotic beverages and health supplements aimed at enhancing digestive health. Their product lineup includes juice drinks, probiotic shots, fast melts, and prebiotic sparkling water, all designed to provide convenient and tasty ways for consumers to incorporate probiotics into their daily routines. GoodBelly is particularly known for its use of the Lactobacillus plantarum 299v strain, which has been extensively researched and is recognized for its effectiveness in promoting gut health. The company has received $12 million in funding as of June 2018, which supports its operations and product development. GoodBelly's mission is to improve human nutrition through natural foods and scientifically validated ingredients, making it a notable player in the probiotic supplement industry.

22. Nutribiótica S.L.

• Website: nutribiotica.es
• Ownership type: Private
• Headquarters: Vigo, Pontevedra, Spain
• Employee distribution: Spain 100%
• Founded year: 2016
• Headcount: 11-50
• LinkedIn: nutribi%c3%b3tica-s.l.

Nutribiótica S.L., based in Vigo, Pontevedra, Spain, is a private health supplement retailer that has been operational since 2016. The company focuses on probiotics and dietary supplements, catering to health-conscious individuals seeking effective solutions for gut health and overall wellness. Nutribiótica offers a range of products, including IV Generation probiotics, which are formulated to enhance gut microbiota. They operate primarily through an online platform, providing easy access to their product range. The company also emphasizes education and awareness, offering resources such as eBooks and a blog that discusses the latest scientific insights on health and microbiota. With a dedicated team of 30 employees, Nutribiótica is committed to innovation and quality in the health supplement sector.

23. Velobiotics

• Website: velobiotics.com
• Ownership type: Private
• Headquarters: Germiston, Gauteng, South Africa
• Employee distribution: South Africa 59%, United Arab Emirates 21%, France 21%
• Founded year: 2015
• Headcount: 1-10
• LinkedIn: vitabiotics-sa-pty-ltd

Velobiotics, founded in 2015 and based in Germiston, Gauteng, South Africa, is a private health and wellness company that specializes in probiotics and dietary supplements. With a small team of around 28 employees, Velobiotics focuses on improving gut health, immune function, and overall well-being through a range of products. Their offerings include solutions for skin, hair, nails, and specific health needs such as female intimate health and children's health. The company employs patented microencapsulation technology, which enhances the delivery and effectiveness of probiotics by protecting them from stomach acid and improving their shelf life. Velobiotics operates an online store and utilizes Amazon for shipping, making their products accessible to a broader audience. Their commitment to quality and innovation positions them as a relevant player in the probiotic supplement industry.

24. Pavia De Mexico

• Website: pavia.mx
• Ownership type: Private
• Headquarters: Leon, Guanajuato, Mexico
• Employee distribution: Mexico 100%
• Founded year: 2016
• Headcount: 11-50
• LinkedIn: pavia-de-mexico

Pavia De Mexico, based in Leon, Guanajuato, Mexico, is a private company founded in 2016 that specializes in probiotic supplements. The company is dedicated to enhancing digestive health and overall wellness through its range of products. Pavia offers various probiotic formulations designed for consumers seeking to improve their health via dietary supplements. Operating primarily through an online store, Pavia ensures easy access to its products for customers. The company has garnered positive feedback from users, with many testimonials praising the effectiveness of its supplements in addressing digestive issues and overall well-being. Pavia's commitment to quality and customer satisfaction is evident in its product offerings and customer service approach.

Probiotic Supplements Insights: Key Companies

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