The healthcare software industry in the US is dynamic, catering to various needs within the medical sector. Companies range from electronic health record (EHR) providers to those focused on telehealth, revenue cycle management, and analytics solutions. As healthcare increasingly relies on tech innovations, these companies play pivotal roles in improving patient care, reducing costs, and enhancing operational efficiencies. With the integration of artificial intelligence and data analytics, the future points towards more personalized health services and streamlined processes. This transformation is driven by an aging population and a growing demand for accessible healthcare solutions.

This list highlights 23 prominent healthcare software companies based in the US, varying in size and specialization. They were founded between 1969 and 2014, with headquarters located in states like Massachusetts, Texas, and Florida. Most companies focus on electronic health records, data management, and other technology solutions aimed at enhancing patient care and operational workflows. With a mixture of corporate and private ownership models, these firms are positioned to shape the future of healthcare technology through innovative offerings.

Read on to uncover the top healthcare software companies in the US.

Top 23 Healthcare Software Companies in the US

1. eClinicalWorks

• Website: eclinicalworks.com
• Ownership type: Corporate
• Headquarters: Westborough, Massachusetts, United States (USA)
• Employee distribution: India 79%, United States (USA) 21%
• Latest funding: $2.2M, October 2022
• Founded year: 1999
• Headcount: 1001-5000
• LinkedIn: eclinicalworks

eClinicalWorks, founded in 1999 and headquartered in Westborough, Massachusetts, is a prominent healthcare IT provider specializing in electronic health records (EHR) and related services. The company employs approximately 6,000 individuals and serves a vast network of healthcare providers, including over 180,000 physicians and 850,000 healthcare professionals globally. eClinicalWorks offers a comprehensive suite of solutions designed to enhance patient engagement, streamline revenue cycle management, and improve healthcare delivery. Their software is utilized in more than 110,000 facilities, showcasing their extensive reach in the healthcare sector. The company is privately held and has shown a commitment to innovation, recently incorporating AI technologies to improve clinical documentation and reduce administrative burdens for healthcare providers. This focus on technology and customer support underscores their role in transforming healthcare practices and enhancing patient care.

2. Meditech

• Website: ehr.meditech.com
• Ownership type: Private Equity
• Headquarters: Canton, Massachusetts, United States (USA)
• Employee distribution: United States (USA) 95%, Other 5%
• Latest funding: $26.0M, September 2022
• Founded year: 1969
• Headcount: 1001-5000
• LinkedIn: meditech

Meditech, officially known as Medical Information Technology, Inc., is a healthcare technology company based in Canton, Massachusetts. Established in 1969, Meditech specializes in electronic health record (EHR) solutions designed to enhance patient care and optimize clinical workflows for healthcare providers. Their flagship product, the Meditech Expanse platform, integrates advanced features such as artificial intelligence, analytics, and cloud capabilities, catering to a wide range of care settings including acute care, ambulatory care, and mental health. Meditech serves a global clientele, with a significant presence in the United States, and has been recognized for its commitment to interoperability and patient engagement. The company has also received funding, with a notable amount of approximately $25.9 million reported in September 2022, reflecting its ongoing efforts to innovate and adapt to the changing demands of the healthcare industry.

3. Change Healthcare

• Website: changehealthcare.com
• Ownership type: Corporate
• Headquarters: Nashville, Tennessee, United States (USA)
• Employee distribution: United States (USA) 85%, Canada 6%, Israel 4%, Other 6%
• Latest funding: $13.0B, January 2021
• Founded year: 2007
• Headcount: 10001+
• LinkedIn: change-healthcare

Change Healthcare Inc. is a healthcare technology provider based in Nashville, Tennessee, established in 2007. The company specializes in solutions that aim to improve the healthcare journey for various stakeholders, including providers, payers, and patients. Their offerings include revenue cycle management, clinical decision support, and data analytics, which help clients enhance operational efficiency and patient engagement. With a workforce exceeding 10,000 employees, Change Healthcare operates primarily in the United States, with a presence in Canada, Israel, and the Philippines. The company has also secured significant funding, amounting to $13 billion, in early 2021, reflecting its robust position in the market and commitment to advancing healthcare technology.

4. CureMD

• Website: curemd.com
• Ownership type: Private
• Headquarters: New York, New York, United States (USA)
• Employee distribution: Pakistan 90%, United States (USA) 9%
• Founded year: 1997
• Headcount: 1001-5000
• LinkedIn: curemd

CureMD is a healthcare technology provider based in New York, specializing in innovative health information systems and services. Founded in 1997, the company has grown to employ over 1,500 individuals, with a significant portion of its workforce located in Pakistan. CureMD offers a range of solutions, including Electronic Health Records, practice management, and medical billing services, primarily targeting hospitals and private practices. Their commitment to improving operational efficiency and compliance is evident in their extensive client base, which includes more than 30,000 practices. Recently, CureMD has focused on developing advanced platforms, such as their oncology solution that integrates AI to enhance patient care and clinical research opportunities. This dedication to innovation and quality service has earned them recognition in the healthcare technology sector.

5. Greenway Health

• Website: greenwayhealth.com
• Ownership type: Private Equity
• Headquarters: Tampa, Florida, United States (USA)
• Employee distribution: India 57%, United States (USA) 41%, Other 1%
• Latest funding: $644.0M, September 2013
• Founded year: 1977
• Headcount: 1001-5000
• LinkedIn: greenway-health

Greenway Health, LLC is a healthcare software provider based in Tampa, Florida, specializing in health information technology solutions. Founded in 1977, the company has built a robust portfolio that includes integrated electronic health records (EHR), practice management, and revenue cycle management services tailored for ambulatory healthcare practices. Greenway Health serves a wide range of healthcare providers, helping them enhance patient care and streamline operations through innovative software solutions. Their product offerings also include telehealth services, patient engagement platforms, and analytics tools, reflecting their commitment to adapting to the evolving needs of the healthcare sector. With a significant portion of their workforce located in India and the United States, they leverage global talent to deliver their services effectively. The company received $644 million in funding in 2013, which has likely supported their growth and development in the competitive healthcare technology market.

6. HealthEdge

• Website: healthedge.com
• Ownership type: Venture Capital
• Headquarters: United States (USA)
• Employee distribution: India 54%, United States (USA) 45%
• Latest funding: $2.6B, April 2025
• Founded year: 2005
• Headcount: 1001-5000
• LinkedIn: healthedge

HealthEdge Software, Inc. is a healthcare technology firm based in the United States, founded in 2005. The company specializes in software solutions designed specifically for healthcare payers, including insurance companies and health plans. Their product offerings include the HealthRules Solutions Suite, which is recognized for its capabilities in claims administration, and GuidingCare, a platform aimed at enhancing care management workflows. Additionally, HealthEdge provides Source, a solution focused on payment integrity, and Wellframe, which aims to improve member engagement through digital care management. With a workforce of approximately 1,921 employees, the company has a significant presence in both the U.S. and India. HealthEdge has also secured substantial funding, amounting to $2.6 billion, which underscores its growth potential and commitment to innovation in the healthcare technology space.

7. CitiusTech

• Website: citiustech.com
• Ownership type: Private Equity
• Headquarters: United States (USA)
• Employee distribution: India 89%, United States (USA) 10%
• Latest funding: October 2022
• Founded year: 2005
• Headcount: 5001-10000
• LinkedIn: citiustech

CitiusTech is a healthcare technology company based in the United States, founded in 2005. With a workforce of nearly 6,000 employees, the company specializes in providing a comprehensive range of services aimed at enhancing operational efficiency and patient outcomes for healthcare organizations. Their client base includes MedTech firms, payers, and providers, reflecting their broad engagement across the healthcare spectrum. CitiusTech's service offerings include data management, consulting, and digital engineering, with a strong emphasis on digital transformation. They have developed various products and solutions, such as the Perform+ suite, which addresses critical areas like revenue cycle management, patient engagement, and interoperability. The company has also made strides in integrating advanced technologies like AI and cloud computing into their services, ensuring they remain at the forefront of healthcare innovation. CitiusTech's commitment to improving healthcare delivery is evident in their focus on quality, regulatory compliance, and patient-centric solutions.

8. Ecaresoft

• Website: ecaresoft.com
• Ownership type: Private
• Headquarters: Austin, Texas, United States (USA)
• Employee distribution: Mexico 64%, United States (USA) 26%, Saudi Arabia 10%
• Founded year: 2010
• Headcount: 51-200
• LinkedIn: ecaresoft-inc.

Ecaresoft, based in Austin, Texas, is a private healthcare software company founded in 2010. The company specializes in developing cloud-based solutions for hospitals and clinics, with a focus on enhancing operational efficiency and patient care management. Their flagship products, Cirrus and Anytime, provide comprehensive tools for managing various aspects of healthcare operations, from billing to electronic medical records. Ecaresoft serves a global clientele, including over 30,000 physicians and numerous healthcare facilities across more than 20 countries. The company emphasizes innovation and aims to transform the relationship between healthcare organizations and technology, striving to make software solutions more user-friendly and effective. Ecaresoft's commitment to driving down healthcare costs and improving access to quality care further underscores its relevance in the healthcare software industry.

9. MediGain

• Website: medigain.com
• Ownership type: Corporate
• Headquarters: Plano, Texas, United States (USA)
• Employee distribution: United States (USA) 37%, Sri Lanka 37%, India 27%
• Latest funding: $7.0M, October 2016
• Founded year: 2004
• Headcount: 201-500
• LinkedIn: medigain

MediGain, known as CareCloud, is a healthcare technology provider based in Plano, Texas. Founded in 2004, the company specializes in delivering a comprehensive suite of cloud-based solutions tailored for healthcare providers. Their offerings include revenue cycle management, electronic health records, telehealth services, and practice management tools. CareCloud serves a wide range of clients, from small medical practices to large health systems, helping them streamline operations and enhance patient care. The company has a global workforce, with significant employee distribution in the United States, Sri Lanka, and India. In 2016, CareCloud secured $7 million in funding, which has likely supported their growth and innovation in the healthcare technology space.

10. ModMed

• Website: modmed.com
• Ownership type: Private
• Headquarters: Boca Raton, Florida, United States (USA)
• Employee distribution: United States (USA) 90%, India 6%, Chile 3%
• Founded year: 2010
• Headcount: 1001-5000
• LinkedIn: modernizing-medicine

ModMed, or Modernizing Medicine, Inc., is a healthcare technology firm based in Boca Raton, Florida. Established in 2010, the company specializes in providing electronic health records (EHR) and practice management solutions that cater to various medical specialties. Their software is designed to help healthcare providers improve operational efficiency, enhance patient care, and effectively manage revenue cycles. A distinctive feature of ModMed is its team of practicing physicians who contribute to product development, ensuring that the software meets the specific needs of medical professionals. The company offers a range of solutions, including telehealth, analytics, and revenue cycle management, and has built a reputation for its specialty-specific EHR systems, such as EMA and gGastro. ModMed's commitment to innovation and quality has garnered a significant user base, with over 130,000 specialty medical professionals relying on their technology to optimize practice performance.

11. Innovaccer

• Website: innovaccer.com
• Ownership type: Venture Capital
• Headquarters: San Francisco, California, United States (USA)
• Employee distribution: India 87%, United States (USA) 13%
• Latest funding: January 2025
• Founded year: 2014
• Headcount: 1001-5000
• LinkedIn: innovaccer

Innovaccer Inc., founded in 2014 and based in San Francisco, California, is a healthcare technology company that specializes in providing a comprehensive data activation platform and advanced analytics solutions. The company serves a wide range of clients, including healthcare providers, payers, and life sciences organizations. Innovaccer's primary goal is to enhance patient care, improve operational efficiency, and facilitate data-driven decision-making within the healthcare sector. Their Health Cloud platform integrates healthcare data to support patient-centered care, while their application suite offers advanced tools designed to improve clinical and financial outcomes. Innovaccer has been recognized for its contributions to value-based care and has received accolades such as Best in KLAS for its CRM and Data & Analytics solutions. The company has also demonstrated a strong commitment to innovation, leveraging artificial intelligence to automate processes and provide actionable insights for healthcare professionals.

12. ZeOmega

• Website: zeomega.com
• Ownership type: Private Equity
• Headquarters: Plano, Texas, United States (USA)
• Employee distribution: India 84%, United States (USA) 16%
• Latest funding: October 2020
• Founded year: 2001
• Headcount: 501-1000
• LinkedIn: zeomega

ZeOmega, founded in 2001 and based in Plano, Texas, is a healthcare technology company that specializes in population health management and care management solutions. The company offers the Jiva platform, which provides healthcare plans and systems with tools to improve care delivery and effectively manage chronic conditions. ZeOmega serves a variety of clients, including health care plans, health systems, and government programs, with a focus on enhancing patient outcomes and operational efficiency. The company has a significant presence in the healthcare technology sector, having been recognized as a top performer in the Everest Group’s Care Management Platforms PEAK Matrix Assessment. With a workforce of around 680 employees, primarily based in India and the United States, ZeOmega continues to innovate and expand its offerings to meet the evolving needs of the healthcare industry.

13. MatrixCare

• Website: matrixcare.com
• Ownership type: Corporate
• Headquarters: Bloomington, Minnesota, United States (USA)
• Employee distribution: United States (USA) 76%, India 21%, Canada 2%
• Latest funding: $750.0M, November 2018
• Founded year: 1982
• Headcount: 501-1000
• LinkedIn: matrixcare

MatrixCare, founded in 1982 and based in Bloomington, Minnesota, is a healthcare software provider that specializes in electronic health record (EHR) solutions for home and long-term care providers. The company offers a range of software products designed to enhance operational efficiency and improve patient care across various healthcare settings, including home health, hospice, skilled nursing, and senior living. With a workforce of approximately 728 employees, MatrixCare serves healthcare organizations that aim to elevate their service delivery and ensure compliance with regulatory standards. The company has also secured significant funding, amounting to $750 million in 2018, which underscores its growth trajectory and commitment to innovation in the healthcare technology space.

14. Medhost

• Website: medhost.com
• Ownership type: Corporate
• Headquarters: Franklin, Tennessee, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: December 2023
• Founded year: 1984
• Headcount: 501-1000
• LinkedIn: medhost

Medhost, based in Franklin, Tennessee, is a health information technology company that specializes in providing electronic health record (EHR) systems, emergency department information systems (EDIS), and revenue cycle management solutions. Founded in 1984, Medhost has over 35 years of experience in the healthcare technology sector. The company aims to improve patient care and operational efficiency for hospitals and healthcare facilities through its integrated technology solutions. Medhost's offerings include a comprehensive clinical suite, financial solutions, and patient engagement tools, all designed to streamline workflows and enhance the overall healthcare experience. The company has a strong focus on interoperability, ensuring that its systems can communicate effectively with other healthcare technologies. Medhost also emphasizes customer support and education, which are critical for successful implementation and ongoing use of their systems.

15. Practice Fusion from Veradigm

• Website: practicefusion.com
• Ownership type: Corporate
• Headquarters: San Francisco, California, United States (USA)
• Employee distribution: United States (USA) 92%, India 4%, Indonesia 4%
• Latest funding: $100.0M, January 2018
• Founded year: 2005
• Headcount: 201-500
• LinkedIn: practice-fusion

Practice Fusion, a healthcare technology company based in San Francisco, California, specializes in providing a cloud-based electronic health record (EHR) platform designed specifically for independent medical practices. Founded in 2005, the company has grown to support approximately 30,000 medical practices, facilitating around 5 million patient visits each month. Their platform offers a range of services, including customizable charting, electronic prescribing, and patient engagement solutions, all aimed at streamlining healthcare delivery. Practice Fusion's EHR is recognized for its user-friendly interface and adaptability to various medical specialties, making it a preferred choice for solo and small practices. The company has also received significant funding, with a reported last funding amount of $100 million in January 2018, which underscores investor confidence in its business model and growth potential.

16. eMDs

• Website: emds.com
• Ownership type: Private
• Headquarters: Austin, Texas, United States (USA)
• Employee distribution: India 81%, United States (USA) 18%
• Founded year: 1996
• Headcount: 501-1000
• LinkedIn: e-mds

eMDs, a company founded in 1996 and based in Austin, Texas, is a prominent provider of healthcare technology solutions. Now operating under the umbrella of CompuGroup Medical, eMDs focuses on delivering software solutions that streamline electronic health records (EHR), practice management, and billing services. Their products are tailored to meet the needs of healthcare providers, including physicians and hospitals, aiming to enhance operational efficiency and improve patient care. eMDs has built its reputation on the foundation of user-centric design, with software developed by practicing physicians who understand the intricacies of patient care and practice management. The company has a significant presence in the U.S. healthcare market, serving a wide range of practices and emphasizing timely reimbursements and patient engagement through integrated tools. eMDs is recognized for its commitment to improving healthcare delivery and has been involved in various initiatives to enhance interoperability and streamline workflows for healthcare providers.

17. Harris Healthcare

• Website: harrishealthcare.com
• Ownership type: Corporate
• Headquarters: Niagara Falls, New York, United States (USA)
• Employee distribution: United States (USA) 59%, Canada 23%, United Kingdom (UK) 4%, Other 14%
• Latest funding: February 2006
• Founded year: 1993
• Headcount: 501-1000
• LinkedIn: harris-healthcare

Harris Healthcare, founded in 1993 and based in Niagara Falls, New York, is a healthcare software provider dedicated to delivering innovative digital health solutions. The company specializes in a variety of products aimed at improving patient care and operational efficiency for healthcare organizations. Their offerings include electronic health records (EHR), telehealth services, and patient management systems, which are designed to enhance clinical workflows and patient safety. Harris Healthcare primarily serves hospitals and healthcare providers, focusing on solutions that facilitate better communication and data management across the care continuum. With a workforce of around 200 employees, the company has a notable presence in the United States, Canada, the United Kingdom, India, and Costa Rica, reflecting its international reach. Harris Healthcare has not reported any recent funding, indicating a stable operational model that relies on its established product suite and market presence.

18. WellSky

• Website: wellsky.com
• Ownership type: Private Equity
• Headquarters: Overland Park, Kansas, United States (USA)
• Employee distribution: United States (USA) 91%, India 6%, Other 3%
• Latest funding: July 2020
• Founded year: 1980
• Headcount: 1001-5000
• LinkedIn: wellsky

WellSky is a healthcare technology company based in Overland Park, Kansas, founded in 1980. The company specializes in software solutions and services designed to enhance care delivery across various healthcare settings. WellSky's offerings cater to home health, hospice, rehabilitation, and analytics, enabling healthcare providers, payers, and community organizations to improve patient outcomes and streamline operations. With a workforce of approximately 1,969 employees, WellSky operates primarily in the United States, with a small presence in India and other regions. The company serves over 20,000 clients, including hospitals, health systems, and community-based organizations, and boasts a remarkable client retention rate of 96%. WellSky's focus on whole person care and addressing social determinants of health reflects its commitment to tackling the complexities of modern healthcare delivery.

19. DrChrono by EverHealth

• Website: drchrono.com
• Ownership type: Corporate
• Headquarters: Orlando, Florida, United States (USA)
• Employee distribution: United States (USA) 78%, India 18%, Canada 4%
• Latest funding: November 2021
• Founded year: 2009
• Headcount: 51-200
• LinkedIn: drchrono

DrChrono by EverHealth, founded in 2009 and based in Orlando, Florida, is a healthcare technology company that provides a comprehensive suite of electronic health records (EHR), practice management, and medical billing solutions. The company operates primarily through a Software as a Service (SaaS) model, allowing healthcare providers to streamline their operations and enhance patient care. DrChrono's platform is designed to cater to various medical specialties, offering customizable clinical tools and workflows that improve efficiency and reduce errors. The company has made significant strides in mobile healthcare technology, being the first to develop EHR applications for iPad and iPhone, and is recognized as an official Apple Mobility Partner. Their services include telehealth capabilities, revenue cycle management, and a patient portal, all aimed at optimizing the healthcare experience for both providers and patients. DrChrono's commitment to innovation is evident in their API offerings, which allow for integration with other healthcare applications, further enhancing their value proposition in the industry.

20. iatricSystems

• Website: iatric.com
• Ownership type: Corporate
• Headquarters: Daytona Beach, Florida, United States (USA)
• Employee distribution: United States (USA) 96%, Costa Rica 4%
• Latest funding: August 2018
• Founded year: 2005
• Headcount: 51-200
• LinkedIn: iatric-systems

iatricSystems, founded in 2005 and based in Daytona Beach, Florida, is a healthcare IT solutions provider that specializes in enhancing patient care through innovative software solutions. The company offers a comprehensive suite of services, including patient privacy monitoring, data management, and EHR integration. Their products are designed to help healthcare organizations navigate complex regulatory environments while improving operational efficiency. iatricSystems operates primarily through a SaaS model, allowing for scalable and flexible solutions that can adapt to the evolving needs of healthcare providers. With a focus on critical areas such as drug diversion monitoring and clinical documentation, iatricSystems has established itself as a valuable partner for healthcare organizations looking to optimize their IT infrastructure and ensure compliance with industry standards.

21. PracticeSuite, Inc.

• Website: practicesuite.com
• Ownership type: Private
• Headquarters: Tampa, Florida, United States (USA)
• Employee distribution: India 81%, United States (USA) 17%, Costa Rica 2%
• Founded year: 2004
• Headcount: 201-500
• LinkedIn: practicesuite-inc-web-based-medical-billing-and-practice-management-software

PracticeSuite, Inc., founded in 2004 and based in Tampa, Florida, is a private company that provides medical practice management software. The firm offers a comprehensive suite of solutions tailored for healthcare providers, including electronic health records (EHR), medical billing services, and patient engagement tools. Their software is designed to streamline operations and improve revenue cycle management for medical practices and billing companies. With a workforce of around 175 employees, the company has built a user base of over 92,000 medical professionals, processing more than $10 billion in claims annually. PracticeSuite has achieved certifications such as SOC2® for data security and ONC certification for their EHR, underscoring their commitment to quality and compliance in the healthcare technology space. The company operates primarily with a significant portion of its workforce based in India, which supports its operations and service delivery.

22. RLDatix

• Website: rldatix.com
• Ownership type: Private Equity
• Headquarters: Chicago, Illinois, United States (USA)
• Employee distribution: North Macedonia 27%, United States (USA) 24%, United Kingdom (UK) 22%, Other 27%
• Latest funding: Other (Debt), $2.0B, February 2024
• Founded year: 1997
• Headcount: 1001-5000
• LinkedIn: rldatix

RLDatix, founded in 1997 and based in Chicago, Illinois, is a healthcare technology provider that specializes in software solutions for risk management and compliance. The company offers a suite of tools designed to assist healthcare organizations in incident reporting, maintaining risk registers, and issuing safety alerts. Their primary clientele includes hospitals and care providers, reflecting their commitment to enhancing operational efficiency and patient safety. RLDatix operates on a Software as a Service (SaaS) model, which allows for scalable and flexible solutions tailored to the needs of healthcare institutions. With a workforce of over 1,200 employees distributed across several countries, including the United States, the UK, and Canada, RLDatix has established a significant presence in the healthcare technology market. The company recently secured $2 billion in funding, indicating strong investor confidence in their business model and growth trajectory. Their involvement in initiatives like the LFPSE (Learning from Patient Safety Events) further highlights their dedication to improving patient safety standards in healthcare.

23. Lightbeam Health Solutions

• Website: lightbeamhealth.com
• Ownership type: Venture Capital
• Headquarters: Dallas, Texas, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: February 2016
• Founded year: 2013
• Headcount: 201-500
• LinkedIn: lightbeamhealth

Lightbeam Health Solutions, based in Dallas, Texas, is a healthcare technology company that has been operational since 2013. The firm specializes in population health management and value-based care services, providing a suite of solutions that includes healthcare analytics, care management, and advisory services. Their offerings are designed to assist healthcare organizations in enhancing patient outcomes while effectively managing costs. Lightbeam has made significant strides in the industry, generating over $2.5 billion in savings through the Medicare Shared Savings Program and more than $4 billion across various value-based contracts since its inception. The company has also received multiple accolades, including recognition as a finalist for the Microsoft Partner of the Year in 2024 and various awards from KLAS and Black Book, underscoring its commitment to innovation and excellence in healthcare technology.

Healthcare Software Insights: Key Companies in the US

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