The pharmaceuticals industry in Illinois is noteworthy for its robust development and distribution of critical medications. It consists of a mix of companies that produce injectable drugs, specialty pharmaceuticals, and innovative biotech therapies. As the demand for effective treatments grows, the state is increasingly focusing on advancements in generics and biologics to enhance patient access. Trends indicate a shift towards personalized medicine and biosimilars, allowing healthcare providers to better meet the specific needs of patients. Moreover, investment in research and development paves the way for breakthrough therapies that could reshape patient care over the next decade.

The companies listed here range in size from small startups to medium-sized corporations, predominantly located in Chicago and its suburbs. Established within the last two decades, these firms focus on various segments—from specialty pharmaceuticals to biopharma and generics. Their operations involve innovative drug development, production of injectables, and distribution of medical supplies. With a workforce that varies from a handful to several hundred, their collective impact on Illinois' pharmaceutical landscape is significant and dynamic.

Continue reading to learn about the top pharmaceuticals companies in Illinois.

Top 22 Pharmaceuticals Companies in Illinois

1. Sagent Pharmaceuticals

• Website: sagentpharma.com
• Ownership type: Corporate
• Headquarters: Schaumburg, Illinois, United States (USA)
• Employee distribution: United States (USA) 84%, India 14%, Other 2%
• Latest funding: $736.0M, July 2016
• Founded year: 2006
• Headcount: 51-200
• LinkedIn: sagent-pharmacueticals

Sagent Pharmaceuticals, based in Schaumburg, Illinois, is a pharmaceutical company that specializes in the development and distribution of injectable medications. Established in 2006, Sagent aims to enhance patient safety through innovative product labeling and packaging. The company primarily serves healthcare providers, including hospitals and clinics, ensuring they have access to reliable injectable products essential for patient care. Sagent's product portfolio includes a range of injectable medications, with recent launches such as PLERIXAFOR and NELARABINE injections. Their commitment to safety is further highlighted by their PreventIV Measures initiative, which focuses on improving product identification and reducing medication errors. With a workforce of approximately 226 employees, Sagent maintains a strong presence in the U.S. market, supported by a global network that enhances their operational capabilities.

2. Medexus Pharmaceuticals

• Website: medexuspharma.com
• Ownership type: Private
• Headquarters: Chicago, Illinois, United States (USA)
• Employee distribution: United States (USA) 50%, Canada 50%
• Founded year: 2012
• Headcount: 51-200
• LinkedIn: medexuspharma

Medexus Pharmaceuticals, Inc. is a private pharmaceutical company based in Chicago, Illinois, with a workforce of approximately 108 employees. Founded in 2012, the company has carved out a niche in the specialty pharmaceutical market, focusing on innovative prescription and over-the-counter medications. Their product portfolio targets various diseases, including allergy, dermatology, hematology, oncology, and rheumatology, with a particular emphasis on rare conditions. Medexus operates primarily in North America, with a balanced employee distribution between the U.S. and Canada. The company was formed through the amalgamation of three established firms, enhancing its capabilities and market reach. Medexus is committed to improving patient outcomes through its products and has built a robust commercial platform to support its growth strategy. They actively seek to license or acquire products that meet essential healthcare needs, demonstrating a proactive approach to business development.

3. Pinnacle Biologics, Inc.

• Website: pinnaclebiologics.com
• Ownership type: Private
• Headquarters: Bannockburn, Illinois, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: $1.5M, December 2011
• Founded year: 2007
• Headcount: 11-50
• LinkedIn: pinnacle-biologics-inc-

Pinnacle Biologics, Inc., founded in 2007 and based in Bannockburn, Illinois, is a specialty pharmaceutical company dedicated to enhancing critical therapies for patients facing serious health challenges. The company specializes in revitalizing older pharmaceutical brands while also supporting the development of newer therapies. Their focus primarily serves healthcare professionals and patients who require effective treatment options. Pinnacle Biologics operates with a fully integrated approach, which includes a dedicated specialty sales force and marketing support, allowing them to effectively reach and serve their target markets. They have a portfolio that includes products like PHOTOFRIN®, which is used in photodynamic therapy, highlighting their commitment to innovative treatment solutions. Although the company has not reported recent funding, their operational capabilities and strategic focus on patient care underscore their relevance in the pharmaceutical sector.

4. Meitheal Pharmaceuticals, Inc.

• Website: meithealpharma.com
• Ownership type: Private
• Headquarters: Chicago, Illinois, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: Other (Debt), $35.0M, August 2023
• Founded year: 2017
• Headcount: 51-200
• LinkedIn: meitheal-pharmaceuticals-inc.

Meitheal Pharmaceuticals, Inc., based in Chicago, Illinois, is a biopharmaceutical company dedicated to developing and commercializing affordable medications. Founded in 2017, the company specializes in generics, biologics, and fertility treatments, aiming to enhance access to essential medicines for healthcare providers and patients alike. Meitheal's mission revolves around addressing unmet needs in the biopharma industry through innovative solutions and strategic partnerships. Their recent acquisition of YUSIMRY® marks their entry into the biosimilars market, further expanding their product offerings. With a workforce of 51-200 employees, Meitheal is actively involved in the pharmaceutical sector, focusing on improving treatment accessibility and patient outcomes. The company has also secured $35 million in funding in August 2023, reflecting strong investor interest in their initiatives and growth potential.

5. TerSera Therapeutics

• Website: tersera.com
• Ownership type: Private Equity
• Headquarters: Deerfield, Illinois, United States (USA)
• Employee distribution: United States (USA) 89%, Canada 11%
• Latest funding: March 2016
• Founded year: 2016
• Headcount: 51-200
• LinkedIn: tersera

TerSera Therapeutics LLC, founded in 2016 and based in Deerfield, Illinois, is a biopharmaceutical company dedicated to developing innovative therapeutics aimed at addressing unmet medical needs. The company primarily focuses on oncology and non-opioid pain management, areas where effective treatments are often lacking. TerSera not only develops specialized medications but also provides comprehensive patient support services, ensuring that healthcare providers and patients have access to the necessary resources for effective treatment. Their approach combines clinical expertise with a patient-first mentality, striving to deliver therapeutics that can significantly improve patient outcomes. With a workforce of around 200 employees, TerSera operates primarily in the United States, with a smaller presence in Canada. The company has not reported any recent funding, indicating a stable operational model since its inception.

6. Nexus Pharmaceuticals, Inc.

• Website: nexuspharma.net
• Ownership type: Family Owned
• Headquarters: Lincolnshire, Illinois, United States (USA)
• Founded year: 2003
• Headcount: 51-200
• LinkedIn: nexus-pharmaceuticals-inc-

Nexus Pharmaceuticals, Inc. is a pharmaceutical manufacturer based in Lincolnshire, Illinois, specializing in the development and production of specialty and generic injectable drugs. Established in 2003 by chemists Mariam S. Darsot and Shahid Ahmed, the company has positioned itself as a key player in addressing critical shortages in the healthcare market. Nexus operates a state-of-the-art manufacturing facility in the U.S., ensuring that their products meet stringent quality and compliance standards. Their portfolio includes several first-to-market FDA-approved generic drugs across various therapeutic categories, including oncology and cardiovascular treatments. The company is committed to providing reliable access to life-saving medications, making them a crucial partner for healthcare providers and organizations. Nexus is also recognized as a certified minority and woman-owned business, reflecting their commitment to diversity and inclusion within the industry.

7. Paragon Biosciences

• Website: paragonbiosci.com
• Ownership type: Private
• Headquarters: Chicago, Illinois, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: $185.0M, November 2022
• Founded year: 2010
• Headcount: 11-50
• LinkedIn: paragon-biosciences-llc

Paragon Biosciences, founded in 2010 and based in Chicago, Illinois, is a biotechnology firm dedicated to creating, building, and funding innovative biology-based companies. The company focuses on developing treatments for various medical conditions, particularly in the life sciences sector. Paragon's portfolio includes several companies that specialize in pharmaceuticals and therapeutics, such as Emalex Biosciences, which is working on new treatments for central nervous system disorders, and Harmony Biosciences, known for its advancements in sleep-wake disorders. Paragon has also invested in Evozyne, a company utilizing generative AI for drug discovery, and Castle Creek Biosciences, which is developing gene therapies. In November 2022, Paragon secured $185 million in funding, underscoring its commitment to addressing unmet medical needs and accelerating scientific breakthroughs in the pharmaceutical industry.

8. Vanqua Bio

• Website: vanquabio.com
• Ownership type: Venture Capital
• Headquarters: Chicago, Illinois, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: $45.0M, July 2024
• Founded year: 2019
• Headcount: 11-50
• LinkedIn: vanqua-bio

Vanqua Bio, based in Chicago, Illinois, is a biopharmaceutical company established in 2019. The firm is dedicated to developing next-generation medicines aimed at treating neurodegenerative diseases, particularly focusing on conditions like Parkinson's disease and Alzheimer's disease. Their innovative drug development strategy leverages advanced insights into neuronal cell pathways and employs cutting-edge assays to create effective therapies. Vanqua Bio's lead program targets glucocerebrosidase (GCase), a key enzyme linked to Parkinson's disease, and they are also exploring treatments for related disorders. The company has attracted significant venture capital funding, with a recent round totaling approximately $44.98 million, underscoring its potential in the pharmaceutical industry. With a team of experienced scientists and a robust pipeline, Vanqua Bio is positioned to make meaningful contributions to the treatment of neurodegenerative conditions.

9. OWP Pharmaceuticals

• Website: owppharma.com
• Ownership type: Private
• Headquarters: Naperville, Illinois, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: $2.7M, September 2024
• Founded year: 2014
• Headcount: 11-50
• LinkedIn: one-world-pharmaceuticals

OWP Pharmaceuticals, founded in 2014 and based in Naperville, Illinois, is a private pharmaceutical company dedicated to developing and marketing medications for neurological disorders. The company offers products like Subvenite Starter Kits, which serve as a branded generic alternative to Lamictal, a widely used treatment for epilepsy and bipolar disorder. OWP Pharmaceuticals aims to support healthcare providers and patients in the U.S. while also addressing global health disparities. They donate a portion of their profits to ROW Global, an organization focused on enhancing education and treatment for those with neurological disorders in under-resourced regions. With a small team of around 23 employees, OWP is actively engaged in the pharmaceutical market and has recently secured funding to further its initiatives, indicating a commitment to growth and innovation in the field.

10. Aark Pharmaceuticals

• Website: aarkpharma.com
• Ownership type: Private
• Headquarters: Mississippi, Illinois, United States (USA)
• Employee distribution: India 100%
• Founded year: 1995
• Headcount: 51-200
• LinkedIn: aark-pharmaceuticals

Aark Pharmaceuticals, founded in 1995 and based in Mississippi, Illinois, is a private pharmaceutical distributor. The company specializes in supplying a wide array of medicines and medical supplies to healthcare providers, including hospitals and pharmacies. Aark Pharmaceuticals focuses on ensuring timely and reliable access to essential pharmaceuticals across various therapeutic areas, particularly in oncology, cardiology, and immunology. They have established a significant presence in the market, serving over 40,000 customers, which includes retail chains and institutional providers. Aark is also certified for Good Distribution Practices, indicating their commitment to quality and compliance in pharmaceutical distribution. Their operations extend beyond the United States, with a strong network in India, where they cater to both government and private healthcare sectors. Aark Pharmaceuticals is dedicated to enhancing patient care through effective distribution of both generic and branded medicines, as well as medical supplies.

11. AltaThera Pharmaceuticals

• Website: altathera.com
• Ownership type: Venture Capital
• Headquarters: Chicago, Illinois, United States (USA)
• Latest funding: $3.4M, December 2016
• Founded year: 2009
• Headcount: 11-50
• LinkedIn: altathera-pharmaceuticals

AltaThera Pharmaceuticals, based in Chicago, Illinois, is a pharmaceutical company dedicated to enhancing patient care through innovative cardiovascular treatments. Founded in 2009, the company has developed Sotalol IV, a novel formulation of a widely used antiarrhythmic drug. This product allows for the outpatient initiation of treatment for atrial fibrillation, a condition affecting millions globally. By shortening hospital stays and facilitating easier access to treatment, AltaThera aims to alleviate the burden on both patients and healthcare providers. The company operates with a focus on efficiency, effectiveness, and outcomes, striving to optimize care through scientific innovation. With a small team of around 41 employees, AltaThera is backed by venture capital and has raised $3.35 million in funding as of December 2016, indicating a level of investor confidence in their mission and products.

12. Capstone Development Services Co, LLC

• Website: capstonedevservices.com
• Ownership type: Private
• Headquarters: Rosemont, Illinois, United States (USA)
• Employee distribution: United States (USA) 97%, India 3%
• Founded year: 2013
• Headcount: 51-200
• LinkedIn: capstone-development-services-co-llc

Capstone Development Services Co, LLC, founded in 2013 and based in Rosemont, Illinois, is a healthcare company that specializes in the development of complex generic pharmaceuticals and medical devices. The company operates as a shared services organization, partnering with global pharmaceutical and medical device companies to streamline the product development process. Capstone's expertise includes regulatory services, technical project management, and scientific affairs, which help clients navigate the complexities of bringing new healthcare products to market. To date, they have achieved regulatory approvals for more than 20 products in key markets, including the United States, European Union, and Canada. Their team consists of experienced professionals with backgrounds in pharmaceutical research and development, ensuring a high success rate in their partnered projects. Capstone also supports various development partnerships and has established its own commercial pharmaceutical company, Long Grove Pharmaceuticals, which further enhances its footprint in the industry.

13. Patrin Pharma, INC.

• Website: patrinpharma.com
• Ownership type: Private
• Headquarters: Skokie, Illinois, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2005
• Headcount: 1-10
• LinkedIn: patrin-pharma-inc.

Patrin Pharma, INC., founded in 2005 and based in Skokie, Illinois, specializes in the development and marketing of high-quality generic drugs. The company has carved out a niche by focusing on specific markets, providing cost-effective solutions to healthcare providers, including hospitals and pharmacies. Patrin Pharma operates through strategic partnerships, which enhance its product pipeline and market reach. The company has successfully launched over 30 products, with a robust pipeline currently under FDA review. Their commitment to practical innovation and rapid development is evident in their recent FDA approvals for niche products, such as Calcitriol Oral Solution and Pregabalin Oral Solution. Patrin Pharma's operational model includes in-house manufacturing capabilities and a strong distribution network, allowing them to effectively serve various healthcare channels across the United States.

14. Xentria, Inc.

• Website: xentria.com
• Ownership type: Private
• Headquarters: Chicago, Illinois, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: $25.0M, October 2022
• Founded year: 2020
• Headcount: 11-50
• LinkedIn: xentria-inc

Xentria, Inc., founded in 2020 and based in Chicago, Illinois, is a biotechnology firm dedicated to innovative drug development. The company specializes in creating therapeutics for rare diseases, with a particular focus on pulmonary sarcoidosis. Xentria collaborates with academic institutions and industry partners to enhance its research and development efforts. Their services extend to clinical trial management and regulatory guidance, aimed at navigating the complexities of drug approval processes. Recently, Xentria secured $25 million in funding, which underscores its potential and ambition in the life sciences sector. The company is currently advancing its lead candidate, XTMAB-16, through clinical trials, having received Orphan Drug Designation from both the FDA and the European Medicines Agency. This designation highlights the significance of their work in addressing critical health needs for patients suffering from rare conditions.

15. Avenacy

• Website: avenacy.com
• Ownership type: Private
• Headquarters: Schaumburg, Illinois, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: $26.0M, November 2024
• Founded year: 2023
• Headcount: 11-50
• LinkedIn: avenacy

Avenacy is a pharmaceutical company based in Schaumburg, Illinois, specializing in the production and distribution of sterile injectable medications. Founded in 2023, Avenacy aims to serve healthcare providers, including hospitals and outpatient clinics, by providing high-quality products that prioritize patient safety and treatment efficacy. The company is actively building a portfolio of FDA-approved products, with a goal of launching over 25 new items within its first two years. Avenacy emphasizes rigorous quality control and safety measures, ensuring that its products are reliable and effective. Recently, the company secured approximately $26 million in funding, which will support its growth and expansion efforts in the competitive pharmaceutical market.

16. Sparx Biopharmaceutical CORP

• Website: sparxbio.com
• Ownership type: Private
• Headquarters: Mount Prospect, Illinois, United States (USA)
• Employee distribution: United States (USA) 71%, China 29%
• Founded year: 2018
• Headcount: 51-200
• LinkedIn: sparx-therapeutics

Sparx Biopharmaceutical CORP, founded in 2018 and based in Mount Prospect, Illinois, is a private biopharmaceutical company dedicated to the development of innovative antibody therapies and immuno-oncology agents. The company aims to strengthen human immunity through advanced research and development, targeting multiple pathways in cancer treatment. Sparx employs sophisticated technologies, including their SAILING™ platform for antibody discovery and the SYNMAB™ platform for optimizing multi-specific antibodies. Their pipeline includes several candidates in various stages of development, with a notable focus on bispecific antibody drugs. The company serves healthcare providers and pharmaceutical companies, providing effective therapeutic solutions. With a team of experienced professionals from major pharmaceutical backgrounds, Sparx is positioned to make significant contributions to the field of oncology and immunotherapy.

17. Alva-amco Pharmacal Companies, LLC

• Website: alva-amco.com
• Ownership type: Corporate
• Headquarters: Niles, Illinois, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: February 2024
• Founded year: 1904
• Headcount: 11-50
• LinkedIn: alva-amco-pharmacal-companies-inc.

Alva-Amco Pharmacal Companies, LLC, based in Niles, Illinois, has been a player in the health and wellness industry since its inception in 1904. The company specializes in the production of non-prescription pharmaceuticals, dietary supplements, and skin care products. Alva-Amco serves a wide range of consumers seeking effective solutions for various health issues, including pain relief, digestive health, and skin conditions. Their portfolio features over 20 brands, with products like ARTHRITEN for arthritis pain and FUNGICURE for treating fungal infections. Alva-Amco markets its products through pharmacies, supermarkets, and mass merchants across North America and is expanding its reach internationally. The company emphasizes product quality and consumer satisfaction, which has helped it maintain a solid reputation in the industry.

18. Espee Group - Empowering Healthcare

• Website: espeeusa.com
• Ownership type: Private
• Headquarters: Schaumburg, Illinois, United States (USA)
• Employee distribution: India 87%, United States (USA) 13%
• Founded year: 1985
• Headcount: 201-500
• LinkedIn: espee-biopharma-%26-finechem-llc

Espee Group - Empowering Healthcare, founded in 1985 and based in Schaumburg, Illinois, is a healthcare service provider that specializes in pharmaceutical distribution and research support. The company offers a range of services including research and development, bioequivalence studies, and clinical trials support. Their clientele includes pharmaceutical manufacturers, contract research organizations (CROs), and government entities, indicating a broad engagement with various stakeholders in the healthcare sector. Espee Group operates globally, with a significant presence in countries like the USA, India, China, and Turkey. They emphasize compliance and quality in their operations, ensuring reliable supply chains and effective project management. The company has established accredited warehouses in multiple regions, including the US, UK, Europe, Canada, and Japan, which underscores their commitment to maintaining high standards in pharmaceutical distribution. With a workforce that is predominantly based in India, Espee Group leverages its global network to facilitate medical breakthroughs and support the pharmaceutical industry's evolving needs.

19. Precision Dose, Inc.

• Website: precisiondose.com
• Ownership type: Corporate
• Headquarters: South Beloit, Illinois, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: April 2017
• Founded year: 2003
• Headcount: 51-200
• LinkedIn: precision-dose-inc-

Precision Dose, Inc., founded in 2003 and based in South Beloit, Illinois, is a pharmaceutical manufacturer and distributor that specializes in unit-dose packaging solutions. The company serves healthcare providers, including hospitals and pharmacies, by providing a range of pharmaceutical products designed to ensure accurate dosing and enhance patient safety. Their product line includes oral medications packaged in unit-dose cups, pre-filled oral syringes, and blister packs, catering to both retail and institutional markets. Precision Dose has made strides in expanding its portfolio through licensing and product development initiatives, maintaining high standards of quality and service. The company operates entirely within the United States and has a dedicated team with extensive expertise in pharmaceutical manufacturing and distribution.

20. Cour Pharmaceuticals Development Co., Inc.

• Website: courpharma.com
• Ownership type: Venture Capital
• Headquarters: Skokie, Illinois, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: Series A, $105.0M, January 2024
• Founded year: 2015
• Headcount: 11-50
• LinkedIn: cour-pharmaceutical-development-company-inc.

Cour Pharmaceuticals Development Co., Inc., founded in 2015 and based in Skokie, Illinois, is a biotechnology firm dedicated to creating first-in-class therapies that aim to reprogram the immune system for autoimmune diseases. The company has developed a unique nanoparticle platform designed to induce antigen-specific tolerance, which could revolutionize treatment for conditions such as Myasthenia Gravis, Primary Biliary Cholangitis, Type 1 Diabetes, and Celiac Disease. Their lead product, CNP-101, partnered with Takeda, is notable for being the first investigational agent to demonstrate the induction of immune tolerance in celiac disease. Cour Pharmaceuticals is actively engaged in clinical trials, with recent positive results reported for their CNP-104 therapy. The company has also attracted significant venture capital funding, totaling $105 million as of January 2024, which underscores its potential in the pharmaceutical industry.

21. Medefil, Inc.

• Website: medefilinc.com
• Ownership type: Private
• Headquarters: Glendale Heights, Illinois, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1998
• Headcount: 51-200
• LinkedIn: medefil

Medefil, Inc., founded in 1998 and based in Glendale Heights, Illinois, is a specialty pharmaceutical company dedicated to the development, manufacturing, and marketing of injectable products and flush syringes. The company has a strong focus on enhancing patient safety and improving the quality of life through high-quality, reliable products. Medefil operates with a commitment to addressing critical unmet needs in medication delivery, which is evident in their extensive product line that includes Atropine Sulfate Injection, Sterile Water for Injection, and various Heparin Lock Flush Syringes. With a state-of-the-art manufacturing facility and a robust R&D lab, Medefil has positioned itself to innovate and expand its offerings in the injectable market. The company has supplied over one billion sterile prefilled syringe products, showcasing its operational capacity and market presence. Medefil's mission emphasizes the importance of quality, safety, and affordability in its product development, making it a significant contributor to the pharmaceutical industry.

22. Pharma Logistics

• Website: pharmalogistics.com
• Ownership type: Corporate
• Headquarters: Libertyville, Illinois, United States (USA)
• Employee distribution: United States (USA) 86%, India 8%, Other 6%
• Latest funding: July 2024
• Founded year: 1996
• Headcount: 51-200
• LinkedIn: pharma-logistics

Pharma Logistics, founded in 1996 and based in Libertyville, Illinois, is a pharmaceutical logistics provider that specializes in reverse distribution services. The company focuses on managing expired pharmaceuticals, ensuring compliance with regulatory standards, and optimizing cash flow for healthcare facilities, including hospitals and pharmacies. Their service offerings include pharmaceutical return services, waste disposal, and analytics, which are tailored to meet the needs of their clients. Pharma Logistics has built a reputation for reliability and efficiency, providing solutions that help healthcare providers navigate the complexities of pharmaceutical returns. They serve a range of clients, including government entities, retail pharmacies, and closed-door pharmacies, and have recently secured a significant contract with the Department of Defense, highlighting their capability and trustworthiness in the sector. With a workforce of around 319 employees, the company continues to expand its influence in the pharmaceutical logistics space.

Pharmaceuticals Insights: Key Companies in Illinois

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