Pharmaceutical distribution companies are integral to healthcare, acting as the bridge between manufacturers and healthcare facilities. This industry comprises businesses that manage the logistics of drugs, medical supplies, and specialized therapies. Ranging from small independent distributors to large corporations, they ensure timely delivery, inventory management, and compliance with safety standards. Recent trends indicate a growing emphasis on technology, with automation and data analytics reshaping operations. As the demand for personalized medicine rises, distributors are poised to adapt their services to meet evolving market needs, making them essential players in patient care.


The companies listed vary in size and focus, including greater or smaller enterprises. Most are headquartered across key states like South Carolina, Ohio, and California, with founding years spanning from 1934 to 2012. Their specializations differ, highlighting product lines from generic drugs to specialty pharmaceuticals. This showcases not only the breadth of offerings but also the industry’s commitment to serving independent pharmacies, large healthcare systems, and community clinics.


Continue reading to discover the top pharmaceutical distribution companies in the US.


Top 22 Pharmaceutical Distribution Companies in the US


1. Smith Drug Company

  • Website: smithdrug.com
  • Ownership type: Private
  • Headquarters: Spartanburg, South Carolina, United States (USA)
  • Employee distribution: United States (USA) 100%
  • Founded year: 1944
  • Headcount: 201-500
  • LinkedIn: smith-drug-company

Smith Drug Company, based in Spartanburg, South Carolina, is a pharmaceutical distributor that has been serving the industry since 1944. The company specializes in wholesale pharmaceutical distribution and medical supplies, catering primarily to independent pharmacies and long-term care facilities. With a workforce of approximately 269 employees, Smith Drug Company operates multiple distribution centers across the United States, ensuring timely access to medications and medical equipment. Their commitment to exceptional customer service is a cornerstone of their operations, with local representatives available to assist clients directly. The company prides itself on maintaining high customer satisfaction ratings, which they attribute to their personalized service and quick resolution of issues. Smith Drug Company offers a wide range of products, including specialty medications, over-the-counter items, and durable medical equipment. Their focus on independent community pharmacies allows them to provide tailored solutions that help these businesses thrive in a competitive market.


2. Besse Medical

  • Website: besse.com
  • Ownership type: Family Owned
  • Headquarters: West Chester Township, Ohio, United States (USA)
  • Employee distribution: United States (USA) 100%
  • Founded year: 1948
  • Headcount: 51-200
  • LinkedIn: bessemedical

Besse Medical, based in West Chester Township, Ohio, is a family-owned healthcare solutions provider that specializes in the distribution of pharmaceuticals and medical supplies. Established in 1948, the company has built a reputation for supporting community physician practices by offering a comprehensive range of products, including controlled substances and biosimilars. Besse Medical is dedicated to ensuring timely access to essential medications, which is crucial for enhancing patient care and operational efficiency for healthcare practitioners. Their services extend beyond mere distribution; they also provide inventory management solutions and tools designed to optimize the operational aspects of medical practices. As part of the AmerisourceBergen network, Besse Medical benefits from a larger infrastructure, allowing them to maintain a high level of service and product availability. Their focus on community care and specialty solutions positions them as a significant player in the pharmaceutical distribution industry.


3. CuraScript SD by Evernorth


CuraScript SD by Evernorth, founded in 1994 and based in Lake Mary, Florida, operates as a healthcare distributor with a focus on specialty pharmaceuticals. The company provides a range of services designed to support medical providers, including online ordering, inventory management, and group purchasing solutions. Their customer base primarily consists of healthcare practitioners who rely on CuraScript SD for timely access to essential medications and supplies. The company also engages in third-party logistics and offers business intelligence services, which enhance the operational capabilities of their clients. With a workforce of over 500 employees, CuraScript SD is dedicated to improving patient care through efficient distribution practices and personalized service. They have not reported any recent funding, indicating a stable operational model within the industry.


4. FFF Enterprises

  • Website: fffenterprises.com
  • Ownership type: Private
  • Headquarters: Temecula, California, United States (USA)
  • Employee distribution: United States (USA) 97%, Other 3%
  • Founded year: 1988
  • Headcount: 501-1000
  • LinkedIn: fff-enterprises

FFF Enterprises, Inc. is a healthcare and pharmaceutical distribution company based in Temecula, California. Established in 1988, the company specializes in providing critical-care products, vaccines, and specialty pharmaceuticals to healthcare professionals and organizations. FFF Enterprises is dedicated to ensuring the availability of high-quality, counterfeit-free pharmaceuticals, addressing the needs of hospitals and clinics for reliable healthcare solutions. The company operates primarily within the United States, with a workforce of approximately 1,397 employees. Their services include emergency ordering, inventory management, and a robust recall system, which underscores their commitment to supply chain safety and customer care. FFF Enterprises also engages in partnerships with leading manufacturers and industry affiliates, enhancing their product offerings and service capabilities. Their subsidiary, Nufactor, focuses on specialty infusion services, further expanding their reach in the healthcare sector.


5. UNICO La farmacia dei farmacisti SpA

  • Website: unicospa.it
  • Ownership type: Private
  • Headquarters: United States (USA)
  • Employee distribution: Italy 99%
  • Founded year: 2002
  • Headcount: 501-1000
  • LinkedIn: unicospa

UNICO La farmacia dei farmacisti SpA, founded in 2002, is a private pharmaceutical distributor based in Italy. The company is structured as a cooperative, owned by pharmacists, which allows it to cater specifically to the needs of pharmacy operations. UNICO provides a comprehensive suite of services, including inventory management solutions, marketing support, and training programs aimed at improving the efficiency of pharmacies. With a workforce of approximately 461 employees, the company operates primarily in Italy, serving over 7,500 pharmacies and offering a catalog of over 75,000 products. UNICO's innovative approach includes the development of the CAREP system, a centralized automatic replenishment service that utilizes artificial intelligence to optimize inventory management for pharmacies. This commitment to enhancing pharmacy operations and patient service positions UNICO as a relevant entity in the pharmaceutical distribution sector.


6. RelayHealth

  • Website: relayhealth.com
  • Ownership type: Corporate
  • Headquarters: Atlanta, Georgia, United States (USA)
  • Employee distribution: United States (USA) 100%
  • Latest funding: June 2006
  • Founded year: 1990
  • Headcount: 201-500
  • LinkedIn: relayhealth

RelayHealth, a subsidiary of McKesson Corporation, is based in Atlanta, Georgia, and was founded in 1990. The company specializes in healthcare services, particularly in pharmaceutical distribution and technology solutions. RelayHealth serves a variety of clients, including pharmacies, healthcare systems, and biopharmaceutical companies. Their pharmaceutical distribution services include drug ordering for pharmacies, specialty drugs for physician practices, and the distribution of vaccines and over-the-counter products. Additionally, RelayHealth provides consulting and software solutions aimed at improving operational efficiency and patient care. The company has a workforce of approximately 578 employees, all located in the United States, and has not reported any recent funding since 2006.


7. La Farmaceutica S.P.A.


La Farmaceutica S.P.A. is a pharmaceutical distribution company based in Castronno, Italy, with a history dating back to 1961. The company specializes in the delivery of pharmaceutical and para-pharmaceutical products to pharmacies and para-pharmacies across the Lombardy and Piedmont regions. With a workforce of approximately 201-500 employees, La Farmaceutica operates a state-of-the-art automated warehouse that spans 14,000 square meters, housing over 80,000 products. Their logistics capabilities are impressive, with around 40 delivery vehicles making multiple daily trips to ensure timely service. The company prides itself on its strong relationships with major pharmaceutical manufacturers, which enhances its ability to provide a wide range of products efficiently. La Farmaceutica's commitment to quality and customer service has solidified its reputation as a trusted partner in the pharmaceutical distribution sector.


8. HyGen Pharmaceuticals, Inc

  • Website: hygenpharma.com
  • Ownership type: Corporate
  • Headquarters: Redmond, Washington, United States (USA)
  • Employee distribution: United States (USA) 100%
  • Latest funding: $300,000, August 2022
  • Founded year: 1993
  • Headcount: 51-200
  • LinkedIn: hygen-pharmaceuticals-inc

HyGen Pharmaceuticals, Inc. is a pharmaceutical wholesaler based in Redmond, Washington, founded in 1993. The company specializes in the distribution of prescription and specialty pharmaceuticals, including generics, controlled substances, over-the-counter products, and medical supplies. HyGen serves independent pharmacies, long-term care facilities, and mail-order pharmacies nationwide. They leverage modern technology and advanced supply chain management to help their customers navigate the complexities of pharmaceutical distribution. HyGen is recognized for its commitment to customer service and compliance, ensuring patient safety through a secure drug supply chain. The company has received funding, with a reported amount of $300,000 in August 2022, indicating ongoing investment in their operations and capabilities. HyGen's innovative approach and dedication to excellence have earned them accolades, including recognition as one of the fastest-growing private companies in the U.S. by Inc. magazine multiple times.


9. CuraScript, Inc. An Express Scripts Co.


CuraScript, Inc., operating as CuraScript SD, is a healthcare logistics provider based in Lake Mary, Florida. Founded in 1989, the company specializes in the distribution of specialty pharmaceuticals, catering primarily to healthcare providers such as physicians' offices and surgery centers. CuraScript SD offers a comprehensive suite of services, including online ordering, inventory management, and third-party logistics. Their expertise extends to managing complex pharmaceutical products, particularly in areas like rare diseases and gene therapy. As a subsidiary of Express Scripts, CuraScript SD benefits from a robust infrastructure and extensive resources, allowing them to deliver efficient and effective distribution solutions. The company is committed to enhancing patient care by ensuring timely access to necessary medications, thereby playing a crucial role in the healthcare supply chain.


10. NDCHealth

  • Website: ndchealth.com
  • Ownership type: Corporate
  • Headquarters: Atlanta, Georgia, United States (USA)
  • Latest funding: January 2006
  • Founded year: 1967
  • Headcount: 1001-5000
  • LinkedIn: ndchealth

NDCHealth, a subsidiary of McKesson Corporation, has been a key player in the healthcare distribution sector since its founding in 1967. Based in Atlanta, Georgia, the company specializes in pharmaceutical distribution, medical supplies, and pharmacy services. NDCHealth serves a variety of clients, including pharmacies, health systems, and biopharma companies, focusing on enhancing health outcomes through efficient supply chain solutions. Their offerings include drug ordering for pharmacies, specialty drugs for physician practices, and a range of medical supplies. NDCHealth is committed to addressing the challenges of drug shortages and improving access to essential medications, making it a vital component of the healthcare supply chain.


11. LABSCO: Delivering Superior Diagnostics

  • Website: mms.mckesson.com
  • Ownership type: Corporate
  • Headquarters: Louisville, Kentucky, United States (USA)
  • Employee distribution: United States (USA) 100%
  • Latest funding: April 2010
  • Founded year: 1972
  • Headcount: 201-500
  • LinkedIn: labsco-laboratory-supply-company

LABSCO: Delivering Superior Diagnostics, part of McKesson Medical-Surgical, is a corporate entity based in Louisville, Kentucky. Founded in 1972, the company specializes in the distribution of medical supplies and pharmaceuticals to healthcare providers, including hospitals and clinics. With a workforce of approximately 101 employees, LABSCO plays a crucial role in supplying over 300,000 medical products, ensuring high order accuracy and fulfillment rates. Their offerings extend beyond mere distribution; they provide operational solutions aimed at enhancing patient care and improving the efficiency of healthcare operations. LABSCO's services include lab management, inventory management, and patient care solutions, which are essential for modern healthcare environments. Their commitment to quality and customer service is reflected in their extensive product range and specialized consulting services, making them a notable player in the healthcare supply chain.


12. Capital Wholesale Drug Company (Capital Drug)

  • Website: capital-drug.com
  • Ownership type: Family Owned
  • Headquarters: Columbus, Ohio, United States (USA)
  • Employee distribution: United States (USA) 100%
  • Latest funding: Other (Debt), $10.0M, March 2024
  • Founded year: 1948
  • Headcount: 51-200
  • LinkedIn: capital-wholesale-drug-company

Capital Wholesale Drug Company, based in Columbus, Ohio, is a family-owned pharmaceutical distributor that has been serving the healthcare community since 1948. Founded by George D. Richards, the company has evolved over the decades while maintaining a strong focus on customer service and product safety. Capital Drug provides a comprehensive range of products, including branded and generic pharmaceuticals, injectables, and medical supplies. They cater primarily to independent pharmacies, government entities, and healthcare facilities, ensuring timely access to essential medications. The company is licensed in 48 states and is recognized for its commitment to compliance with the Drug Supply Chain Security Act (DSCSA). Recently, Capital Drug secured $10 million in funding, which will likely support their operational enhancements and compliance initiatives. With a dedicated team and a focus on personalized service, Capital Drug continues to play a vital role in the pharmaceutical distribution industry.


13. NDC, Inc.

  • Website: ndc-inc.com
  • Ownership type: Private Equity
  • Headquarters: Nashville, Tennessee, United States (USA)
  • Employee distribution: United States (USA) 95%, Other 5%
  • Latest funding: March 2021
  • Founded year: 1953
  • Headcount: 51-200
  • LinkedIn: national-distribution-%26-contracting

NDC, Inc., founded in 1953 and based in Nashville, Tennessee, operates as a healthcare supply chain company. The firm provides distribution and logistics services tailored to healthcare distributors, manufacturers, and providers. NDC offers a wide array of products, including medical supplies, infusion solutions, and vaccine distribution services. The company supports over 1,200 healthcare distributors and collaborates with nearly 400 manufacturers, enhancing their ability to navigate the complexities of supply chain management. NDC's services extend to various healthcare sectors, including primary care, dental, acute care, and specialty markets. Their commitment to efficiency and customer service is evident in their extensive network and the solutions they provide to their partners.


14. Drogueria DNM FARMA


Drogueria DNM FARMA, established in 1990, is a pharmaceutical distributor based in Argentina. The company specializes in providing a wide array of medications and healthcare solutions tailored for clinics, pharmacies, and public entities. With a strong emphasis on customer service, Drogueria DNM FARMA ensures that its clients have timely access to essential healthcare products. Their logistics capabilities are designed to respond quickly to the needs of over 230 institutions, reflecting their operational efficiency. The company boasts a stock of more than 3,000 product presentations, which allows them to meet various healthcare demands effectively. Their team of experienced professionals is dedicated to offering expert advice and support, further enhancing their service quality in the pharmaceutical distribution sector.


15. HealthSource Distributors


HealthSource Distributors, based in Baltimore, Maryland, is a private pharmaceutical distributor that has been operational since 2003. The company specializes in providing a wide array of brand and generic medications to independent pharmacies, regional chains, and healthcare facilities across the United States. With a workforce of around 34 employees, HealthSource has established itself as a customer-focused distributor, emphasizing efficient and cost-effective delivery of pharmaceutical products. They maintain a state-of-the-art distribution facility, ensuring that all items are tracked by lot and expiration, and they provide authenticated electronic pedigrees for their products. HealthSource is known for its overnight delivery service at no additional cost, which enhances the convenience for its clients. Their approach includes no forced contracts or minimum order requirements, making them an attractive alternative for pharmacies seeking flexibility and savings.


16. NuCare Pharmaceuticals, Inc.

  • Website: nucarerx.com
  • Ownership type: Private
  • Headquarters: Orange, California, United States (USA)
  • Employee distribution: United States (USA) 100%
  • Founded year: 2001
  • Headcount: 1-10
  • LinkedIn: nucare-pharmaceuticals-inc.

NuCare Pharmaceuticals, Inc. is a pharmaceutical distributor based in Orange, California, established in 2001. The company specializes in providing a comprehensive range of medications and medical supplies to healthcare providers, including pharmacies, hospitals, and long-term care facilities. With a strong emphasis on customer service, NuCare has developed robust standard operating procedures that ensure compliance with industry regulations and maintain the integrity of their supply chain. They are fully licensed by the FDA and DEA, which underscores their commitment to safety and reliability. NuCare's product offerings include generic medications, pre-packaged pharmaceuticals, vaccines, and specialty medications, catering to a wide spectrum of healthcare needs. Their operational capabilities include national distribution, climate-controlled storage, and precise pedigree tracing for all products, ensuring that healthcare providers receive the necessary medications when and where they are needed. The company prides itself on its customer-centric approach, providing dedicated account management to support clients in navigating the pharmaceutical market effectively.


17. BluPax Pharma

  • Website: blupaxpharma.com
  • Ownership type: Private
  • Headquarters: Edison, New Jersey, United States (USA)
  • Employee distribution: United States (USA) 100%
  • Founded year: 2012
  • Headcount: 51-200
  • LinkedIn: blupax-pharmaceuticals-llc

BluPax Pharma, based in Edison, New Jersey, is an independently owned pharmaceutical distributor that specializes in the wholesale distribution of prescription drugs, vaccines, and over-the-counter medications. Established in 2012, the company has grown from a small operation with just a few products to a significant player in the pharmaceutical distribution sector, managing a catalog of over 4,000 SKUs. BluPax Pharma serves a variety of clients, including long-term care facilities, independent retail pharmacies, and hospitals, ensuring they have reliable access to essential medications. The company prides itself on its competitive pricing, transparency, and a high fill rate of 99.5%, which is achieved through partnerships with over 120 manufacturers. They are licensed in all 50 states and are compliant with the Drug Supply Chain Security Act (DSCSA), further solidifying their position in the market. BluPax Pharma also emphasizes customer service, offering easy ordering through various platforms and a dedicated account management team to support their clients' needs.


18. Lone Star Pharmaceuticals


Lone Star Pharmaceuticals, based in Argyle, Texas, is a pharmaceutical distributor established in 1996. The company specializes in supplying bulk active pharmaceutical ingredients (APIs), pharmaceutical products, and medical supplies to healthcare providers. With a dedicated team, Lone Star Pharmaceuticals aims to enhance patient care by ensuring that critical medications are readily available. They operate under strict compliance with federal and state regulations, including the Drug Supply Chain Security Act, and maintain licenses to distribute in 47 states. Their commitment to logistics excellence and customer service has earned them a reputation for reliability, particularly in managing medication shortages and providing access to hard-to-find products. Lone Star Pharmaceuticals also engages in international distribution through its subsidiary, One World, expanding its reach beyond the U.S. market.


19. Value Drug Company

  • Website: valuedrugco.com
  • Ownership type: Private
  • Headquarters: Duncansville, Pennsylvania, United States (USA)
  • Employee distribution: United States (USA) 100%
  • Founded year: 1934
  • Headcount: 201-500
  • LinkedIn: value-drug-company

Value Drug Company, based in Duncansville, Pennsylvania, is a private pharmaceutical distributor founded in 1934. The company specializes in providing a wide array of services and products tailored for independent pharmacies. With a workforce of approximately 147 employees, Value Drug Company focuses on enhancing operational efficiency, ensuring compliance with regulatory standards, and offering specialty pharmacy services. Their offerings include a comprehensive product inventory of over 25,000 items, including brand, generic, and specialty pharmaceuticals. They also provide support in navigating the complexities of the healthcare landscape, helping pharmacies to thrive in a competitive market. Value Drug Company has established partnerships with various service providers to assist their members in achieving compliance and operational success. Their commitment to independent pharmacies is evident in their various programs aimed at increasing profitability and efficiency, making them a significant player in the pharmaceutical distribution industry.


20. Safe Chain Solutions, LLC

  • Website: safechain.com
  • Ownership type: Private
  • Headquarters: Cambridge, Maryland, United States (USA)
  • Employee distribution: United States (USA) 100%
  • Founded year: 2011
  • Headcount: 11-50
  • LinkedIn: safe-chain-solutions

Safe Chain Solutions, LLC, founded in 2011 and based in Cambridge, Maryland, operates as a full-service pharmaceutical distributor. The company provides a wide array of pharmaceuticals and healthcare products to healthcare facilities across the United States. With a workforce of approximately 26 employees, Safe Chain has carved out a niche in addressing drug shortages and emergency sourcing needs, ensuring that clients receive necessary products in a timely and secure manner. Their operational model includes same-day shipping and a commitment to no minimum order requirements, which enhances their appeal to various healthcare providers, including hospitals, clinics, and pharmacies. Safe Chain is licensed to distribute controlled substances and has built strong relationships with over 100 manufacturers and wholesalers, positioning itself as a reliable partner in the pharmaceutical supply chain.


21. River City Pharma

  • Website: rivercityrx.com
  • Ownership type: Private
  • Headquarters: Mason, Ohio, United States (USA)
  • Employee distribution: United States (USA) 100%
  • Founded year: 2001
  • Headcount: 51-200
  • LinkedIn: river-city-pharma

River City Pharma, also known as Masters Pharmaceutical, is a pharmaceutical distributor located in Mason, Ohio. Founded in 2001, the company has built a robust network, supplying over 10,000 pharmacies across the United States. Masters Pharmaceutical specializes in a wide array of products, including generic and branded medications, over-the-counter drugs, vaccines, and specialty pharmaceuticals. They pride themselves on sourcing high-quality products at competitive prices, ensuring that pharmacies can meet their patients' needs effectively. The company is fully accredited by the National Association of Boards of Pharmacy (NABP), which underscores their commitment to maintaining stringent standards in pharmaceutical distribution. With a focus on exceptional customer service, Masters Pharmaceutical provides dedicated account management and flexible payment options, making them a trusted partner for independent and small chain pharmacies.


22. J M Smith Corporation

  • Website: jmsmithcorp.com
  • Ownership type: Private
  • Headquarters: Spartanburg, South Carolina, United States (USA)
  • Employee distribution: United States (USA) 100%
  • Founded year: 1944
  • Headcount: 201-500
  • LinkedIn: j-m-smith-corporation

J M Smith Corporation, founded in 1944 and based in Spartanburg, South Carolina, operates as a healthcare and technology company. It specializes in pharmaceutical distribution and medical supplies, serving pharmacies and long-term care facilities throughout the United States. The company is built on core values of integrity, innovation, involvement, and intensity, which guide its operations and customer interactions. J M Smith Corporation includes several business units, with Smith Drug Company being a full-line distributor of pharmaceuticals and medical equipment. Integral Rx, another unit, focuses on providing affordable generics to independent pharmacies. The company is also dedicated to community service, actively engaging in initiatives to combat prescription drug abuse and improve local communities. Through its foundation, J M Smith Corporation has contributed significantly to various charitable causes, demonstrating a commitment to social responsibility alongside its business objectives.



Pharmaceutical Distribution Insights: Key Companies in the US


CompanyHeadquarterSizeFoundedOwnership
Smith Drug CompanySpartanburg, South Carolina, United States (USA)201-5001944Private
Besse MedicalWest Chester Township, Ohio, United States (USA)51-2001948Family Owned
CuraScript SD by EvernorthLake Mary, Florida, United States (USA)201-5001994Private
FFF EnterprisesTemecula, California, United States (USA)501-10001988Private
UNICO La farmacia dei farmacisti SpAUnited States (USA)501-10002002Private
RelayHealthAtlanta, Georgia, United States (USA)201-5001990Corporate
La Farmaceutica S.P.A.United States (USA)201-5001961Private
HyGen Pharmaceuticals, IncRedmond, Washington, United States (USA)51-2001993Corporate
CuraScript, Inc. An Express Scripts Co.Lake Mary, Florida, United States (USA)1001-50001989Private
NDCHealthAtlanta, Georgia, United States (USA)1001-50001967Corporate
LABSCO: Delivering Superior DiagnosticsLouisville, Kentucky, United States (USA)201-5001972Corporate
Capital Wholesale Drug Company (Capital Drug)Columbus, Ohio, United States (USA)51-2001948Family Owned
NDC, Inc.Nashville, Tennessee, United States (USA)51-2001953Private Equity
Drogueria DNM FARMAUnited States (USA)51-2001990Private
HealthSource DistributorsBaltimore, Maryland, United States (USA)51-2002003Private
NuCare Pharmaceuticals, Inc.Orange, California, United States (USA)1-102001Private
BluPax PharmaEdison, New Jersey, United States (USA)51-2002012Private
Lone Star PharmaceuticalsArgyle, Texas, United States (USA)11-501996Private
Value Drug CompanyDuncansville, Pennsylvania, United States (USA)201-5001934Private
Safe Chain Solutions, LLCCambridge, Maryland, United States (USA)11-502011Private
River City PharmaMason, Ohio, United States (USA)51-2002001Private
J M Smith CorporationSpartanburg, South Carolina, United States (USA)201-5001944Private


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