Pennsylvania is a significant hub for pharmaceuticals, characterized by a multitude of companies ranging from small start-ups to established firms. These organizations focus on creating innovative drugs, biologics, and complex formulations to address various health challenges. The industry is witnessing a shift toward personalized medicine and advanced therapies, including gene and cell-based treatments. Collaborations with academic institutions and an emphasis on R&D create a vibrant ecosystem that drives rapid advancements. With increasing regulatory demands and the urgency to tackle antimicrobial resistance, the path ahead holds vast opportunities for growth and innovation in pharmaceutical solutions.

The listing features 21 pharmaceuticals companies located across Pennsylvania, varying in size from small teams to several hundred employees. Founded between 1999 and 2021, these firms thrive in multiple domains, including anti-infectives, oncology, and generics. Notably, locations such as Malvern, Bensalem, and Langhorne play host to these innovative enterprises. Each company operates with unique specializations; for example, Venatorx focuses on resistant bacterial infections, while Braeburn addresses opioid use disorder. Together, these companies contribute significantly to the state's pharmaceutical landscape.

Continue reading to explore the top pharmaceuticals companies in Pennsylvania.

Top 21 Pharmaceuticals Companies Companies in Pennsylvania

1. Venatorx Pharmaceuticals, Inc.

• Website: venatorx.com
• Ownership type: Venture Capital
• Headquarters: Malvern, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: $24.7M, September 2022
• Founded year: 2010
• Headcount: 51-200
• LinkedIn: venatorx-pharmaceuticals-inc.

Venatorx Pharmaceuticals, Inc., founded in 2010 and based in Malvern, Pennsylvania, is a pharmaceutical company dedicated to the discovery and development of novel anti-infectives. The company specializes in creating treatments for multi-drug-resistant bacterial infections and hard-to-treat viral infections, addressing a critical need in modern medicine. Venatorx operates through a strong in-house research and development team, holding over 120 patents related to their innovative therapies. Their lead product, cefepime-taniborbactam, has completed a Phase 3 study and is currently under FDA review for marketing authorization. In 2022, the company secured a significant contract from BARDA, amounting to up to $318 million, to support the development of cefepime-taniborbactam. This funding underscores their commitment to advancing treatments for resistant infections. Venatorx's pipeline also includes other promising candidates, such as ceftibuten-ledaborbactam etzadroxil, which is set to enter Phase 3 trials. Their focus on combating antibiotic resistance positions them as a relevant player in the pharmaceutical industry.

2. Virtus Pharmaceuticals

• Website: virtusrx.com
• Ownership type: Private Equity
• Headquarters: Langhorne, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: Other (Debt), December 2019
• Founded year: 2011
• Headcount: 11-50
• LinkedIn: virtus-pharmaceuticals

Virtus Pharmaceuticals, based in Langhorne, Pennsylvania, is a private equity-owned company founded in 2011. It specializes in delivering innovative pharmaceutical products designed to enhance patient health. The company primarily serves independent pharmacies and drug chains, ensuring that unique medicines are accessible to those who need them. Virtus emphasizes quality and safety in its operations, with a strong focus on pharmacovigilance to maintain high standards for the products it supplies. The leadership team brings extensive experience from various sectors within the pharmaceutical industry, which supports their mission to transform scientific advancements into practical, accessible medicines. Virtus actively seeks partnerships to expand its product offerings and enhance its impact on the healthcare market.

3. Sigmapharm Laboratories, LLC

• Website: sigmapharm.com
• Ownership type: Private
• Headquarters: Bensalem, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 94%, Morocco 6%
• Founded year: 2005
• Headcount: 51-200
• LinkedIn: sigmapharm-laboratories

Sigmapharm Laboratories, LLC, based in Bensalem, Pennsylvania, is a private pharmaceutical company that specializes in the development, manufacturing, and marketing of unique generic and branded drug products. Established in 2005, Sigmapharm has carved out a niche in the pharmaceutical industry by focusing on innovative technologies that address complex drug formulation challenges. The company prides itself on its proprietary systems that optimize drug solubility, bioavailability, and stability, which are critical factors in effective drug delivery. Sigmapharm's product portfolio includes a range of medications, some of which are first-to-market generics, indicating their capability to navigate the competitive landscape effectively. Their state-of-the-art facilities and a dedicated team of professionals support their research and development efforts, allowing them to maintain high standards of quality and safety. Sigmapharm's commitment to ethical practices and transparency further enhances its reputation in the industry, making it a noteworthy player in the pharmaceutical sector.

4. M8 Pharmaceuticals, Inc

• Website: m8pharmaceuticals.com
• Ownership type: Private
• Headquarters: Berwyn, Pennsylvania, United States (USA)
• Employee distribution: Mexico 59%, Brazil 39%, Other 1%
• Latest funding: $125.0M, February 2019
• Founded year: 2007
• Headcount: 201-500
• LinkedIn: moksha8

M8 Pharmaceuticals, Inc. is a biopharmaceutical company based in Berwyn, Pennsylvania, established in 2007. The company specializes in licensing, marketing, and distributing innovative therapeutics across Latin America, with a strong focus on enhancing access to essential medications for healthcare providers and patients. M8 Pharmaceuticals has built a robust portfolio that spans several therapeutic areas, including Central Nervous System, Cardiometabolism, Respiratory, Gastroenterology, Oncology & Hematology, and Rare Diseases. The company has a significant presence in Mexico and Brazil, where it employs local experts to navigate the complexities of these markets. In February 2019, M8 Pharmaceuticals secured $125 million in funding, which underscores investor confidence in its business model and growth potential. Recently, M8 was acquired by Acino, a Swiss pharmaceutical company, which further strengthens its capabilities and market reach in Latin America. Through strategic partnerships and a commitment to patient care, M8 Pharmaceuticals aims to transform the lives of individuals in the region by providing access to innovative and proven medicines.

5. i3 Pharmaceuticals, LLC

• Website: i3pharmaceuticals.com
• Ownership type: Private
• Headquarters: Warminster, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2015
• Headcount: 51-200
• LinkedIn: i3-pharmaceuticals-llc

i3 Pharmaceuticals, LLC, based in Warminster, Pennsylvania, is a private pharmaceutical company that specializes in the development and manufacturing of complex solid oral specialty pharmaceutical products. Established in 2015, the company has quickly made a name for itself by focusing on high-quality medications that meet challenging formulation needs. With a state-of-the-art facility spanning 150,000 square feet, i3 Pharmaceuticals is equipped for extensive research, development, and manufacturing processes. The company has successfully filed several Abbreviated New Drug Applications (ANDAs) with the FDA, gaining approval for products such as Ramelteon and Selegiline HCl. Their mission emphasizes innovation and quality, aiming to improve patient outcomes through their specialized offerings. The team comprises experienced professionals with backgrounds in various pharmaceutical sectors, enhancing their ability to navigate the complexities of drug development and market entry.

6. Jubilant Pharma

• Website: jubilantpharma.com
• Ownership type: Private
• Headquarters: Yardley, Pennsylvania, United States (USA)
• Latest funding: Other (Debt), $400.0M, July 2022
• Founded year: 2014
• Headcount: 1001-5000
• LinkedIn: jubilant-pharma

Jubilant Pharma, founded in 2014 and based in Yardley, Pennsylvania, is a private pharmaceutical company that operates in several key areas of the industry. The company focuses on allergy therapy products, radiopharmaceuticals, and contract manufacturing services. With a product range that includes over 200 allergenic extracts and specialized venom products, Jubilant Pharma serves healthcare providers such as allergists and hospitals. They are recognized as a significant player in the allergy therapy market, particularly in the United States, where they are the sole producer of venom products for allergy treatment. Their commitment to research and development is evident in their efforts to innovate and enhance their product offerings. The company also engages in contract manufacturing, providing services for sterile injectables and other pharmaceutical products. In July 2022, Jubilant Pharma secured $400 million in funding, which supports their ongoing operations and growth initiatives. This financial backing, combined with their specialized focus and market presence, positions Jubilant Pharma as a relevant entity in the pharmaceutical industry.

7. Tavotek Biotherapeutics

• Website: tavotek.com
• Ownership type: Corporate
• Headquarters: Lower Gwynedd Township, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 68%, China 32%
• Latest funding: Series B, $35.0M, November 2021
• Founded year: 2019
• Headcount: 11-50
• LinkedIn: tavotek

Tavotek Biotherapeutics, based in Lower Gwynedd Township, Pennsylvania, is a biopharmaceutical company dedicated to discovering, developing, and commercializing therapeutic medicines for patients with serious diseases. Founded in 2019, Tavotek operates with a focus on addressing significant unmet medical needs, particularly in the fields of cancer and autoimmune conditions. The company utilizes advanced research and development platforms, including TavoSelect™, TavoPrecise™, and TavoELITE™, to create innovative treatment options. Tavotek's pipeline includes multiple product candidates in various stages of development, reflecting their commitment to tackling challenging health issues. The company has also established a global presence, with operations in both the United States and China. In November 2021, Tavotek raised $35 million in a Series B funding round, which has bolstered their research initiatives and clinical trials.

8. KVK Tech, Inc.

• Website: kvktech.com
• Ownership type: Private
• Headquarters: Newtown, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2004
• Headcount: 501-1000
• LinkedIn: kvk-tech-inc-

KVK Tech, Inc., founded in 2004 and based in Newtown, Pennsylvania, is a pharmaceutical manufacturer dedicated to the development and production of FDA-approved generic and specialty brand medications. The company aims to provide affordable alternatives to high-cost brand medicines, serving pharmacies, healthcare providers, and patients. KVK Tech operates entirely within the United States, ensuring that all products are manufactured in compliance with FDA, DEA, and DEP guidelines. Their operations include a strong focus on research and development, as well as manufacturing and distribution. KVK Tech is actively expanding its capabilities, including the construction of a new sterile injectable plant, which reflects their commitment to addressing unmet patient needs and enhancing their product portfolio. The company emphasizes quality and integrity in its operations, striving to meet the challenges of today's healthcare system by making medications accessible to a broader range of patients.

9. Spark Therapeutics, Inc.

• Website: sparktx.com
• Ownership type: Corporate
• Headquarters: Philadelphia, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: $4.3B, February 2019
• Founded year: 2013
• Headcount: 501-1000
• LinkedIn: spark-therapeutics-inc

Spark Therapeutics, Inc., founded in 2013 and based in Philadelphia, Pennsylvania, is a biotechnology company dedicated to developing gene therapy treatments for genetic diseases. Their primary focus includes conditions such as hemophilia and inherited retinal diseases. Spark aims to provide innovative therapies that offer long-lasting effects, significantly improving patient care. The company operates a fully integrated model that combines research, development, and manufacturing of gene therapies. They are particularly noted for their investigational therapies that target specific genetic disorders, leveraging advancements in understanding the human genome. Spark Therapeutics is also a member of the Roche Group, which enhances their capabilities in drug development and commercialization. Their recent funding of $4.3 billion in 2019 underscores their potential for growth and innovation in the pharmaceutical industry.

10. Genus Lifesciences Inc.

• Website: genuslifesciences.com
• Ownership type: Private
• Headquarters: Allentown, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1999
• Headcount: 51-200
• LinkedIn: genus-lifesciences-inc

Genus Lifesciences Inc., founded in 1999 and based in Allentown, Pennsylvania, operates as a private pharmaceutical manufacturer. The company focuses on the production of both branded and generic drugs, with a particular emphasis on obtaining FDA approvals for drugs that were previously marketed without proper authorization. This initiative is vital in addressing public health concerns related to unapproved medications. Genus Lifesciences employs a team of over 150 professionals who engage in various aspects of pharmaceutical operations, from research and development to quality assurance. Their products are distributed widely across the United States, reaching pharmacies, hospitals, and other healthcare providers. The company also emphasizes good manufacturing practices (GMPs) to ensure that their products meet high-quality standards. With a robust pipeline of new drug applications, Genus Lifesciences is actively involved in the pharmaceutical industry, contributing to the development of safe and effective medications.

11. Braeburn

• Website: braeburnrx.com
• Ownership type: Private
• Headquarters: Plymouth Meeting, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 98%, Other 2%
• Latest funding: Other (Debt), $110.0M, January 2018
• Founded year: 2012
• Headcount: 51-200
• LinkedIn: braeburn

Braeburn is a pharmaceutical company based in Plymouth Meeting, Pennsylvania, founded in 2012. The company is dedicated to transforming the management of opioid use disorder (OUD), a complex condition that affects millions of individuals. Braeburn's mission centers on providing innovative treatment solutions and support for those impacted by OUD. They work closely with healthcare providers and community organizations to enhance access to care and combat the stigma surrounding addiction. Braeburn's product, BRIXADI, is designed to assist individuals in their recovery journey. The company has received significant funding, totaling $110 million, to support its initiatives and research efforts. Braeburn is also involved in community advocacy, emphasizing the importance of education and destigmatization in addressing the opioid crisis. Their commitment to research and development further underscores their role in the pharmaceutical industry, as they seek to advance treatment options and improve patient outcomes.

12. Evrys Bio

• Website: evrysbio.com
• Ownership type: Private
• Headquarters: Doylestown, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: $34.3M, July 2021
• Founded year: 2012
• Headcount: 1-10
• LinkedIn: forge-life-science

Evrys Bio, founded in 2012 and based in Doylestown, Pennsylvania, is a biotechnology company dedicated to developing next-generation antiviral therapies. The company is pioneering a novel approach by targeting human proteins known as sirtuins, which play a crucial role in the body's immune response to viral infections. This innovative strategy aims to create broad-spectrum antivirals that can effectively combat various viral diseases, including hepatitis B and C, as well as respiratory infections. Evrys Bio's pipeline includes several promising drug discovery programs, such as treatments for pan-respiratory infections and a single pill for immunosuppressed patients to protect against multiple opportunistic infections. The company has received $34.3 million in funding as of July 2021, which underscores its potential and the interest it has garnered within the biotechnology sector. Evrys Bio's commitment to addressing significant clinical challenges positions it as a noteworthy player in the pharmaceutical industry.

13. Amring Pharmaceuticals Inc.

• Website: amringusa.com
• Ownership type: Private
• Headquarters: Berwyn, Pennsylvania, United States (USA)
• Founded year: 2014
• Headcount: 11-50
• LinkedIn: amring-pharmaceuticals-inc-

Amring Pharmaceuticals Inc., now known as Nordic Pharma, Inc., is a pharmaceutical company based in Berwyn, Pennsylvania. Established in 2014, the company specializes in the development and distribution of generic medications, focusing on unique generics that cater to niche markets. Their mission is to promote health across communities by providing reliable, safe, and affordable medications that enhance the quality of life for patients. Amring has built a reputation for its commitment to quality, working closely with development, production, and supply chain partners who share their values. The company has a vertically integrated supply chain, which allows for better oversight of manufacturing processes. Their product portfolio includes generics for complex conditions, and they actively seek partnerships to expand their offerings. Amring has shown growth through product launches and acquisitions, indicating a proactive approach to meeting market demands. They have also participated in various industry events, showcasing their commitment to remaining engaged in the pharmaceutical community.

14. Duchesnay USA

• Website: duchesnayusa.com
• Ownership type: Family Owned
• Headquarters: Rosemont, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2012
• Headcount: 51-200
• LinkedIn: info-duchesnayusa-com

Duchesnay USA, founded in 2012 and based in Rosemont, Pennsylvania, is a family-owned pharmaceutical company dedicated to women's health. The company offers therapeutic options tailored for women at various life stages, including pregnancy and menopause. Their product portfolio includes Bonjesta®, Osphena®, and Diclegis®, which are designed to address specific health needs. Duchesnay USA emphasizes the importance of safety and efficacy in their medications, reflecting a commitment to high standards of product quality. As a member of the Duchesnay Pharmaceutical Group, they leverage a legacy of innovation in women's health that began in Canada in 1970. The company has established itself as a key player in the specialty pharmaceutical market, focusing on the unique health challenges faced by women. Their operations are entirely based in the United States, ensuring that they can respond effectively to the needs of their primary customer base: women seeking reliable health solutions.

15. SK Life Science Labs

• Website: sklslabs.com
• Ownership type: Private
• Headquarters: King Of Prussia, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2021
• Headcount: 11-50
• LinkedIn: proteovant-therapeutics

SK Life Science Labs, based in King of Prussia, Pennsylvania, is a biotechnology firm that specializes in drug discovery and development. Founded in 2021, the company is a subsidiary of SK Biopharmaceuticals and is part of the larger SK Group. The company is dedicated to creating innovative therapies for oncology and immunology, leveraging advanced platforms such as targeted protein degradation and the proprietary MOPED™ molecular glue platform. Their work aims to improve patient outcomes by developing degrader medicines that target historically difficult-to-treat diseases. With a team that boasts over 120 years of combined experience in research and development, SK Life Science Labs is positioned to collaborate with pharmaceutical companies and research institutions to advance treatment solutions. Their pipeline includes multiple programs aimed at addressing significant health challenges, particularly in cancer and immunological disorders.

16. Aqua Pharmaceuticals, an Almirall Company

• Website: aquapharm.com
• Ownership type: Corporate
• Headquarters: Exton, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: December 2013
• Founded year: 2004
• Headcount: 51-200
• LinkedIn: aqua-pharmaceuticals

Aqua Pharmaceuticals, an Almirall Company, is a pharmaceutical firm based in Exton, Pennsylvania, with a focus on dermatology. Founded in 2004, the company is dedicated to developing and manufacturing innovative prescription medicines aimed at treating various skin conditions, including acne, actinic keratosis, dermatitis, and impetigo. Aqua Pharmaceuticals serves healthcare professionals and patients, striving to enhance skin health and improve quality of life through effective treatments. As part of Almirall, a global player in dermatology, Aqua Pharmaceuticals benefits from a robust research and development framework, allowing it to introduce cutting-edge therapies to the market. The company operates solely in the United States, ensuring a concentrated effort in addressing the skin health needs of the American population.

17. Nordic Pharma, Inc.

• Website: nordicpharmausa.com
• Ownership type: Private
• Headquarters: Berwyn, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 85%, Canada 8%, Romania 8%
• Founded year: 2014
• Headcount: 11-50
• LinkedIn: amring-pharmaceuticals-inc-

Nordic Pharma, Inc., based in Berwyn, Pennsylvania, is a private pharmaceutical company founded in 2014. The company specializes in the development and distribution of generic medications, focusing on delivering safe, reliable, and affordable drugs to healthcare providers, pharmacies, and hospitals. Their operations include manufacturing and supplying a range of generic pharmaceuticals, with a particular emphasis on products that address specific market needs. Nordic Pharma is committed to promoting health across communities by ensuring access to quality medications. They have a vertically integrated supply chain, which enhances their ability to oversee manufacturing and sourcing. The company has a strong emphasis on partnerships, seeking to collaborate with others who share their commitment to quality and patient care. Their product portfolio includes unique generics that are strategically positioned to meet market demands, reflecting their focus on quality over quantity.

18. Peptilogics

• Website: peptilogics.com
• Ownership type: Venture Capital
• Headquarters: Pittsburgh, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: Other (Grant), January 2022
• Founded year: 2013
• Headcount: 11-50
• LinkedIn: peptilogics

Peptilogics is a biotechnology firm based in Pittsburgh, Pennsylvania, founded in 2013. The company specializes in peptide therapeutics, aiming to revolutionize drug discovery and development for serious infections, particularly periprosthetic joint infections (PJI). Their lead program, PLG0206, is an investigational antibiotic peptide that has shown significant potential in preclinical studies and is currently undergoing clinical trials. Peptilogics employs a unique combination of peptide research and artificial intelligence to optimize drug design, allowing for the exploration of new therapeutic options. The company is committed to addressing high unmet medical needs and collaborates with healthcare professionals to advance its innovative solutions. Peptilogics has received FDA orphan drug designation for PLG0206, highlighting its focus on critical health challenges.

19. Womens Choice Pharmaceuticals

• Website: wcpharma.com
• Ownership type: Private
• Headquarters: Berwyn, Pennsylvania, United States (USA)
• Founded year: 2009
• Headcount: 51-200
• LinkedIn: women%27s-choice-pharmaceuticals

Womens Choice Pharmaceuticals, now known as EDW Pharma, is a private pharmaceutical company based in Paoli, Pennsylvania. Founded in 2009, the company specializes in the development and commercialization of therapeutic solutions primarily in neurology, women's health, and urology. EDW Pharma markets a range of prescription products designed to meet specific health needs, catering to both healthcare providers and patients. Their notable products include TIGLUTIK®, an oral suspension for ALS, and Urogesic Blue™, a urinary antiseptic. The company operates with a focus on providing impactful medicines in therapeutic areas that have historically been underserved. With a dedicated team and a commitment to patient care, EDW Pharma aims to make a positive difference in the lives of those they serve.

20. Penn Life Sciences

• Website: pennlifesciences.com
• Ownership type: Private
• Headquarters: Langhorne, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2004
• Headcount: 51-200
• LinkedIn: pennlifesciences

Penn Life Sciences, founded in 2004 and based in Langhorne, Pennsylvania, is a private pharmaceutical manufacturer dedicated to addressing significant drug shortages in the United States. The company specializes in the development and production of FDA-approved medicines, focusing on high-quality and affordable alternatives to meet the needs of healthcare providers and organizations. Their operations include a robust CDMO partnership, allowing them to collaborate effectively in pharmaceutical manufacturing. With a facility designed to exceed industry standards, Penn Life Sciences is committed to maintaining the highest manufacturing practices while ensuring compliance with FDA, DEA, and DEP guidelines. Their mission emphasizes alleviating domestic drug shortages and increasing transparency with regulatory bodies, showcasing their proactive stance in the pharmaceutical industry.

21. Particle Sciences, A Lubrizol Life Science Company

• Website: particlesciences.com
• Ownership type: Corporate
• Headquarters: Bethlehem, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: December 2023
• Founded year: 1991
• Headcount: 51-200
• LinkedIn: particlesciencesinc

Particle Sciences, A Lubrizol Life Science Company, is a pharmaceutical contract development and manufacturing organization (CDMO) based in Bethlehem, Pennsylvania. Founded in 1991, the company specializes in providing comprehensive services that include active pharmaceutical ingredient (API) development, drug product formulation, and cGMP manufacturing for both clinical trials and commercial production. Their expertise spans a range of dosage forms, including injectables, topical, and long-acting implants. Particle Sciences serves a global clientele, primarily pharmaceutical companies, by offering tailored solutions that ensure compliance with regulatory standards. Their facilities are equipped to handle complex formulations and high-potency APIs, making them a valuable partner in the drug development process. The company has not reported any recent funding, indicating a stable operational model focused on delivering quality services to their clients.

Pharmaceuticals Companies Insights: Key Companies in Pennsylvania

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