Indiana hosts a robust healthcare software industry, focusing on solutions that streamline patient care, improve operational efficiency, and enhance data management. Companies here range from startups to well-established firms, offering products like electronic health records, revenue cycle management, and telehealth solutions. New technologies such as artificial intelligence and data analytics are increasingly shaping the future, driving innovations that deliver quality care while managing costs. Notably, organizations are prioritizing interoperability to facilitate seamless data exchange among systems, highlighting an industry trend toward collaboration to foster healthier communities.

This list features a mix of sizable and smaller healthcare software companies headquarter in Indiana, having been founded from 1986 to 2021. Among them are giants like Legato Health Technologies and smaller innovators such as Blue Agilis. Their specializations range from revenue cycle management and occupational health software to advanced analytics and compliance solutions, showcasing the sector's adaptability in addressing contemporary healthcare challenges.

Continue reading to discover the top healthcare software companies in Indiana.

Top 21 Healthcare Software Companies in Indiana

1. Medical Informatics Engineering, Inc

• Website: mieweb.com
• Ownership type: Private
• Headquarters: Fort Wayne, Indiana, United States (USA)
• Founded year: 1995
• Headcount: 51-200
• LinkedIn: medical-informatics-engineering-inc

Medical Informatics Engineering, Inc. (MIE) is a healthcare technology company based in Fort Wayne, Indiana, established in 1995. The firm specializes in creating innovative software solutions aimed at enhancing the practice of medicine. MIE's product suite includes Enterprise Health, a comprehensive occupational health software; WebChart, one of the first certified electronic medical records systems for ambulatory settings; and BlueHive, which assists in compliance and operational efficiency for healthcare providers. The company serves a variety of clients, including hospitals, health systems, and Fortune 500 employers, emphasizing their role in improving healthcare delivery. MIE has positioned itself as an innovation engine in the healthcare sector, focusing on web-based applications and health information technology that support clinicians and administrators in their daily operations. Their commitment to continuous improvement and adaptation to the evolving needs of healthcare providers underscores their relevance in the industry.

2. Legato Health Technologies

• Website: legato.com
• Ownership type: Corporate
• Headquarters: Indianapolis, Indiana, United States (USA)
• Latest funding: $1.2B, July 2003
• Founded year: 1988
• Headcount: 10001+
• LinkedIn: legato-health-technologies

Legato Health Technologies, now operating as Carelon Global Solutions, is a healthcare technology firm based in Indianapolis, Indiana. Founded in 1988, the company has evolved to focus on digital transformation services specifically designed for healthcare systems. Carelon provides a range of solutions including data and digital services, IT support, and business operations assistance. Their expertise lies in helping health plans, employers, and government agencies streamline processes and enhance operational efficiency. With over 12,500 employees, Carelon leverages its extensive experience to address complex healthcare challenges, aiming to simplify and modernize healthcare operations. The company has delivered significant value to its clients, showcasing its impact in the industry.

3. Enterprise Health

• Website: enterprisehealth.com
• Ownership type: Private
• Headquarters: Fort Wayne, Indiana, United States (USA)
• Employee distribution: United States (USA) 96%, Brazil 4%
• Founded year: 1995
• Headcount: 51-200
• LinkedIn: enterprisehealth

Enterprise Health, founded in 1995 and based in Fort Wayne, Indiana, is a private healthcare technology company that specializes in occupational health software solutions. With a workforce of approximately 76 employees, the company has carved out a niche in managing employee health through a comprehensive suite of products. Their offerings include immunization management, medical surveillance, and primary care services, all designed to help large employers and health systems enhance employee wellness and ensure compliance with health regulations. Enterprise Health's solutions are particularly relevant in today's environment, where organizations are increasingly focused on employee health management, especially in light of challenges posed by the COVID-19 pandemic. The company prides itself on its certified EHR, which integrates occupational health and compliance functionalities, making it a valuable tool for employers looking to streamline their health management processes. Their commitment to interoperability and robust reporting capabilities further supports their clients in making informed decisions about employee health.

4. Ascension Health (Formerly Navion Healthcare Solutions)

• Website: navionhcs.com
• Ownership type: Private
• Headquarters: Indianapolis, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1986
• Headcount: 51-200
• LinkedIn: navion-healthcare-solutions

Ascension Health, formerly known as Navion Healthcare Solutions, is a healthcare data services and software provider based in Indianapolis, Indiana. Founded in 1986, the company has dedicated over three decades to developing effective data strategies and integrated software tools aimed at improving patient outcomes. Their primary offerings include the Ncompass registry software, which facilitates streamlined data capture and reporting for healthcare organizations. This software is particularly valuable for quality improvement initiatives, allowing healthcare providers to manage clinical data efficiently. Ascension Health also provides data abstraction services, employing a team of nurses to ensure high-quality data management. Their commitment to personalized service and trusted data has enabled them to build strong relationships with clients across the healthcare sector, ultimately driving better outcomes for patients and communities. The company operates entirely within the United States and focuses on delivering actionable insights through their software solutions.

5. Zotec Partners

• Website: zotecpartners.com
• Ownership type: Private
• Headquarters: Carmel, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: Other (Debt), November 2023
• Founded year: 1998
• Headcount: 1001-5000
• LinkedIn: zotec-partners

Zotec Partners, founded in 1998 and based in Carmel, Indiana, is a healthcare technology company that specializes in revenue cycle management (RCM) solutions. The company focuses on helping healthcare organizations optimize their financial operations and improve patient financial experiences through advanced technology and tailored processes. Zotec offers a comprehensive suite of services, including end-to-end RCM, patient solutions that enhance engagement, and robust analytics to drive decision-making. Their proprietary technology is designed to streamline operations, increase collections, and ensure compliance with industry standards. Zotec has established itself as a trusted partner for healthcare providers, managing significant annual collections and serving over 21,000 providers nationwide. Their commitment to innovation is reflected in their continuous investment in technology and processes aimed at improving the revenue cycle function for their clients.

6. GoRev

• Website: gorev.com
• Ownership type: Private
• Headquarters: Carmel, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2015
• Headcount: 11-50
• LinkedIn: venture-development-llc

GoRev, founded in 2015 and based in Carmel, Indiana, is a healthcare software provider under the umbrella of Venture Development. The company specializes in a full-featured Health Information System that integrates various functionalities essential for healthcare facilities. Their offerings include a Laboratory Information Management System (LIMS), revenue cycle management, and tools specifically designed for micro-hospitals and free-standing emergency rooms. GoRev has made significant strides in the healthcare sector, reportedly servicing around 30% of the free-standing emergency room market in Texas and expanding into other states. The company prides itself on its active development process, continuously enhancing its software to meet evolving healthcare regulations and client needs. Their commitment to customer service is evident, with support available around the clock, ensuring that healthcare providers can rely on their systems at all times.

7. IncreMedical

• Website: incremedical.com
• Ownership type: Private
• Headquarters: Saint John, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1999
• Headcount: 201-500
• LinkedIn: incremedical

IncreMedical, founded in 1999 and based in Saint John, Indiana, is a private healthcare management company that focuses on innovative solutions for care management, analytics, and IT services. With a workforce of approximately 98 employees, IncreMedical serves a variety of clients, including healthcare providers, health plans, employers, and patients. Their mission is to optimize care delivery and enhance patient outcomes through their proprietary software and advisory services. The company offers a range of solutions, such as post-acute care optimization, longitudinal care management, and IT and analytics services. Their proprietary software, MedAdept®, integrates analytics and clinical decision support to improve efficiencies and create cost-effective care delivery models. IncreMedical's expertise in post-acute care management and their commitment to value-based care make them a significant player in the healthcare software industry.

8. PolicyStat

• Website: policystat.com
• Ownership type: Corporate
• Headquarters: Carmel, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: May 2017
• Founded year: 2006
• Headcount: 11-50
• LinkedIn: policystat

PolicyStat, now part of RLDatix, is a healthcare technology company based in Carmel, Indiana. Founded in 2006, the company specializes in providing integrated software solutions aimed at enhancing patient safety and operational efficiency for healthcare organizations. Their product suite includes tools for governance, risk management, compliance, and workforce management, which are crucial for healthcare providers navigating complex regulatory environments. PolicyStat has established a significant presence in the industry, serving over 6,000 organizations globally. Their commitment to improving care quality and safety is evident in their partnerships with various healthcare entities, including providers and insurers. Although they have not reported any recent funding, their ongoing operations and expansion of services, such as the acquisition of SocialClimb, reflect their active engagement in the healthcare software market.

9. Netlink Inc

• Website: netlinkinc.net
• Ownership type: Private
• Headquarters: Indianapolis, Indiana, United States (USA)
• Founded year: 2000
• Headcount: 1-10
• LinkedIn: netlink-inc

Netlink Inc, founded in 2000 and based in Indianapolis, Indiana, operates as a private healthcare technology company. The firm specializes in providing health information systems and mobile applications tailored for various healthcare settings, including hospitals and clinics. Their flagship product, mNUSA, is designed to enhance patient management and streamline healthcare operations, making it easier for healthcare professionals to access and manage medical data. The company emphasizes the modularity and responsiveness of its solutions, ensuring compatibility across devices and ease of use for different healthcare roles, from administrators to medical staff. Despite its small team size, Netlink Inc is committed to delivering innovative solutions that address the evolving needs of the healthcare industry.

10. Orchard Software

• Website: orchardsoft.com
• Ownership type: Private Equity
• Headquarters: Carmel, Indiana, United States (USA)
• Employee distribution: United States (USA) 99%, Other 1%
• Latest funding: September 2019
• Founded year: 1993
• Headcount: 201-500
• LinkedIn: orchard-software

Orchard Software, founded in 1993 and based in Carmel, Indiana, is a healthcare technology company that specializes in laboratory information systems (LIS). The company offers a comprehensive suite of products designed to improve the efficiency and productivity of laboratories in various sectors, including hospitals, public health, and private practices. Orchard Software operates primarily through a Software as a Service (SaaS) model, providing cloud-based solutions that facilitate seamless integration and management of laboratory operations. With a focus on customer support and usability, Orchard has built a robust reputation in the industry, serving over 2,100 customers and maintaining a high customer satisfaction rating. Their solutions cater to a wide range of laboratory specialties, including molecular testing, pathology, and toxicology, showcasing their adaptability to the evolving needs of the healthcare sector.

11. Blue Agilis

• Website: blueagilis.com
• Ownership type: Venture Capital
• Headquarters: Carmel, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: Seed, $2.5M, March 2023
• Founded year: 2021
• Headcount: 11-50
• LinkedIn: blue-agilis

Blue Agilis, founded in 2021 and based in Carmel, Indiana, is a healthcare technology firm dedicated to improving population health management. The company provides an AI-enabled clinical improvement platform designed to enhance care outcomes and operational efficiencies for payers, provider groups, and health systems. Their focus on value-based care is evident in their offerings, which include tools for assessing practice maturity and implementing evidence-based interventions. The team at Blue Agilis consists of physician-scientists, clinicians, and population health experts, all committed to transforming healthcare delivery. Recently, they secured $2.5 million in seed funding in March 2023, which underscores their potential for innovation and growth in the healthcare software space.

12. Prevounce Health

• Website: prevounce.com
• Ownership type: Venture Capital
• Headquarters: Indianapolis, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: Series A, $2.5M, October 2023
• Founded year: 2016
• Headcount: 11-50
• LinkedIn: prevounce

Prevounce Health, founded in 2016 and based in Indianapolis, Indiana, is a healthcare technology firm that provides innovative solutions for remote patient monitoring and care management. The company offers a cloud-based platform that integrates various services, including chronic care management, annual wellness visits, and preventive services. Prevounce Health aims to enhance patient outcomes while ensuring compliance with healthcare regulations. Their product line includes clinically validated, cellular-connected devices that monitor vital health metrics such as blood pressure, weight, blood glucose, and blood oxygen levels. With a recent funding round of $2.5 million in October 2023, Prevounce is positioned to expand its offerings and continue its mission of improving healthcare delivery. The company serves a range of clients, including healthcare practices, health systems, and payors, making it a significant player in the healthcare software industry.

13. Olio

• Website: olio.health
• Ownership type: Private Equity
• Headquarters: Indianapolis, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: Series A, $13.0M, August 2022
• Founded year: 2017
• Headcount: 11-50
• LinkedIn: oliohealth

Olio is a healthcare technology firm based in Indianapolis, Indiana, founded in 2017. The company specializes in software solutions that facilitate patient co-management and enhance communication among care teams. Olio's platform is designed for various healthcare entities, including health plans, hospitals, and physician groups, with a focus on value-based care. By streamlining processes and promoting accountability, Olio aims to improve patient outcomes and reduce unnecessary readmissions. The company has received $13 million in Series A funding in August 2022, which underscores its growth potential and the confidence investors have in its mission. Olio's software is particularly noted for its ability to connect care teams across different settings, thereby optimizing patient management and care coordination.

14. Kodiak Solutions

• Website: kodiaksolutions.io
• Ownership type: Private
• Headquarters: Indianapolis, Indiana, United States (USA)
• Employee distribution: United States (USA) 98%, India 2%
• Founded year: 2005
• Headcount: 201-500
• LinkedIn: kodiak-solutions

Kodiak Solutions, founded in 2005 and based in Indianapolis, Indiana, is a private healthcare technology provider specializing in advanced solutions for revenue cycle management and compliance. With a workforce of approximately 456 employees, the company has established itself as a key player in the healthcare software industry. Kodiak Solutions serves a wide array of clients, including over 1,900 hospitals and 250,000 physicians across the United States. Their cloud-based platform, known as Revenue Cycle Analytics (RCA), leverages a comprehensive data pool to deliver actionable insights, improve net revenue, and enhance operational efficiency. The company’s services include detailed reporting, risk management, and compliance support, all aimed at helping healthcare organizations navigate the complexities of financial processes. Kodiak Solutions has not reported any recent funding, indicating a stable operational model without external financial dependencies.

15. WoundVision

• Website: woundvision.com
• Ownership type: Private
• Headquarters: Indianapolis, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2008
• Headcount: 11-50
• LinkedIn: woundvision

WoundVision, based in Indianapolis, Indiana, is a healthcare technology firm founded in 2008. The company specializes in advanced wound imaging and documentation solutions, aiming to improve patient care and streamline processes for healthcare providers. Their flagship product, the WoundVision Scout, is notable for its ability to provide both anatomical and physiological documentation, allowing for precise wound assessment. WoundVision's solutions are designed to integrate seamlessly with electronic medical record (EMR) systems, which helps reduce documentation errors and enhances workflow efficiency. The company has received FDA 510(k) clearance for its products, ensuring compliance with regulatory standards. WoundVision actively participates in the healthcare community, offering educational resources and tools to help clinicians improve wound care outcomes. Their commitment to innovation and quality positions them as a significant player in the healthcare software industry.

16. HealthCall

• Website: healthcall.com
• Ownership type: Venture Capital
• Headquarters: Crown Point, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: Seed, $100,000, July 2016
• Founded year: 2003
• Headcount: 51-200
• LinkedIn: healthcall-llc

HealthCall, based in Crown Point, Indiana, is a healthcare technology firm established in 2003. The company focuses on advancing care delivery through innovative solutions tailored for healthcare providers, including emergency medical services and hospitals. Their offerings include remote patient monitoring, telehealth services, and a comprehensive care delivery platform that integrates electronic health records with patient engagement tools. HealthCall's technology is designed to enhance communication between care professionals and patients, ultimately aiming to improve health outcomes and operational efficiency. The company has received seed funding, which supports its ongoing development and expansion in the healthcare technology space. HealthCall's solutions are utilized across various challenging environments, including homes, shelters, and correctional facilities, demonstrating their adaptability and commitment to addressing the needs of diverse patient populations.

17. CMB Solutions, Inc.

• Website: cmbsolutionsinc.com
• Ownership type: Private
• Headquarters: Indianapolis, Indiana, United States (USA)
• Employee distribution: India 50%, United States (USA) 50%
• Founded year: 2009
• Headcount: 11-50
• LinkedIn: cmb-solutions-inc-

CMB Solutions, Inc., founded in 2009 and based in Indianapolis, Indiana, is a private healthcare service provider that focuses on patient engagement solutions for home medical equipment. The company offers a range of services designed to improve patient adherence and operational efficiency for healthcare providers. Their offerings include compliance campaigns, resupply management, and risk management tools, all aimed at enhancing patient engagement and reducing readmission rates. CMB Solutions operates with a hybrid model, allowing patients to choose their preferred method of communication, which helps maximize contact rates. The company integrates with various healthcare technologies, ensuring a streamlined workflow for their clients. With a workforce split evenly between the United States and India, CMB Solutions demonstrates a commitment to providing dedicated support and customized solutions to their clients in the healthcare sector.

18. Clinical Architecture

• Website: clinicalarchitecture.com
• Ownership type: Private
• Headquarters: Carmel, Indiana, United States (USA)
• Employee distribution: United States (USA) 98%, Other 2%
• Founded year: 2007
• Headcount: 51-200
• LinkedIn: clinical-architecture

Clinical Architecture, founded in 2007 and based in Carmel, Indiana, is a healthcare technology firm specializing in data quality and interoperability solutions. The company provides software and professional services that enable healthcare organizations to manage clinical data more effectively. Their flagship product, Symedical, is designed to enhance data quality and facilitate interoperability, making clinical data a valuable asset for healthcare providers. Clinical Architecture works with a variety of clients, including prominent health systems like CommonSpirit Health and Montefiore Medical Center, as well as government entities such as the CDC. Their expertise in terminology management and data normalization is crucial for organizations aiming to improve patient outcomes and streamline data processes. The company has not reported any recent funding, indicating a stable operational model without external financial backing. Clinical Architecture's commitment to enhancing healthcare data quality positions it as a significant player in the healthcare software sector.

19. Mandolin

• Website: mandolin.com
• Ownership type: Venture Capital
• Headquarters: Indianapolis, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: Series A, $12.0M, June 2021
• Founded year: 2020
• Headcount: 1-10
• LinkedIn: withmandolin

Mandolin is a healthcare technology firm based in Indianapolis, Indiana, founded in 2020. The company specializes in AI-driven solutions tailored for infusion centers, aiming to streamline operations and enhance patient care. By automating back office tasks within existing electronic health record (EHR) systems, Mandolin helps clinics reduce administrative burdens and focus more on patient treatment. Their AI is trained on extensive data related to buy-and-bill processes, payer policies, and financial assistance programs, allowing it to manage various tasks efficiently. With over 110 clinics utilizing their services, Mandolin is carving out a niche in the infusion industry. The company secured $12 million in Series A funding in June 2021, reflecting its potential for growth and innovation in healthcare technology.

20. LifeOmic

• Website: lifeomic.com
• Ownership type: Corporate
• Headquarters: Indianapolis, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: December 2023
• Founded year: 2016
• Headcount: 51-200
• LinkedIn: lifeomic-inc.

LifeOmic is a healthcare technology company based in Indianapolis, Indiana, founded in 2016. The company specializes in precision health solutions, aiming to improve patient outcomes through advanced data management and integration. LifeOmic's offerings include the LifeOmic Platform, which serves as a technology backbone for healthcare providers and researchers, enabling them to manage complex health data effectively. Their products, such as LifeOmic AI Consult, leverage machine learning to assist clinicians in generating accurate medical summaries, thereby enhancing efficiency in patient care. LifeOmic collaborates with various healthcare organizations, including Indiana University Health, to drive innovation in the field. The company is committed to empowering healthcare teams and individuals with the tools necessary for informed decision-making in health management.

21. hc1

• Website: hc1.com
• Ownership type: Private Equity
• Headquarters: Indianapolis, Indiana, United States (USA)
• Employee distribution: United States (USA) 84%, United Kingdom (UK) 16%
• Latest funding: $6.2M, January 2025
• Founded year: 2011
• Headcount: 51-200
• LinkedIn: hc1

hc1, founded in 2011 and based in Indianapolis, Indiana, is a healthcare technology company that specializes in software solutions tailored for laboratories and health systems. The company provides a suite of products, including hc1 Performance Analytics™, hc1 Operations Management™, hc1 PrecisionDx Advisor™, and hc1 Workforce Optimization™, all designed to enhance lab efficiency and improve patient care. By leveraging data-driven insights, hc1 helps diagnostic laboratories and health systems optimize their operations, reduce costs, and deliver personalized care. The company has established partnerships with key players in the healthcare sector, such as Quest Diagnostics and Beckman Coulter, further solidifying its presence in the industry. Recently, hc1 secured $6.25 million in funding, reflecting ongoing investor interest and support for its innovative solutions. With a focus on real-time insights and operational management, hc1 is positioned to address significant challenges faced by laboratories today.

Healthcare Software Insights: Key Companies in Indiana

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