Indiana's biopharmaceutical sector focuses on exploring novel therapies and advancing healthcare solutions. The industry features companies engaged in research, drug manufacturing, and clinical trials, all contributing to crucial medical advancements. With a thriving ecosystem fueled by innovation and investment, the future promises growth in personalized medicine, biologics, and advanced drug delivery systems. Indiana serves as a hub, benefiting from its proximity to prominent universities and research institutions, and the potential for collaboration. This dynamic environment positions Indiana as a significant player in the biopharmaceutical landscape, driving initiatives that address pressing health challenges worldwide.

The companies on this list range from small startups founded in recent years to well-established firms with decades of history. Headquartered across various cities in Indiana, such as Carmel and Indianapolis, they specialize in critical areas like gene therapy, drug delivery systems, and clinical research services. With sizes varying between 11-5000 employees, these companies collectively contribute to advancing healthcare solutions. Their innovative approaches reflect a commitment to tackling both common and rare health conditions, showcasing the state’s robust biopharmaceutical industry and the dedication to improving patient outcomes.

Continue reading to discover the notable biopharmaceutical companies in Indiana.

Top 21 Biopharmaceutical Companies Companies in Indiana

1. Sudo Biosciences

• Website: sudobio.com
• Ownership type: Private Equity
• Headquarters: Carmel, Indiana, United States (USA)
• Employee distribution: United States (USA) 50%, United Kingdom (UK) 50%
• Latest funding: Series B, $30.0M, February 2024
• Founded year: 2020
• Headcount: 11-50
• LinkedIn: sudo-biosciences

Sudo Biosciences is a biopharmaceutical company based in Carmel, Indiana, dedicated to designing and developing novel medicines that aim to transform patients' lives. The company specializes in TYK2 inhibitors, targeting the pseudokinase domain of the TYK2 enzyme, which plays a crucial role in cytokine signaling pathways associated with various immune-mediated inflammatory conditions. Their pipeline includes a potential first- and best-in-class brain-penetrant candidate for treating multiple sclerosis and neurodegenerative diseases, as well as a topical candidate for immune-mediated dermatologic diseases. Founded in 2020, Sudo has quickly gained traction in the industry, securing $147 million in Series B funding to advance its clinical programs. This funding reflects the company's potential to address significant unmet medical needs in the treatment of autoimmune and neurologic conditions.

2. Eradivir

• Website: eradivir.com
• Ownership type: Venture Capital
• Headquarters: West Lafayette, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: Other (Grant), $1.0M, September 2024
• Founded year: 2020
• Headcount: 11-50
• LinkedIn: eradivir

Eradivir is a biotechnology company based in West Lafayette, Indiana, founded in 2020. The firm specializes in developing antiviral therapeutics, with a primary focus on influenza and other respiratory infections. Utilizing a unique platform of small molecule immunotherapies, Eradivir aims to enhance the immune system's ability to combat diseases. Their lead molecule, EV25, has shown promising results in preclinical studies, outperforming existing treatments for influenza. The company is currently preparing to initiate Phase I clinical trials for EV25, demonstrating their commitment to advancing their research initiatives. Eradivir has also attracted significant funding, including a recent $10.25 million Series A round, which will support their clinical studies and further development of their therapeutic pipeline. With a dedicated team of industry experts and a clear vision for addressing viral infections, Eradivir is positioned to make a meaningful impact in the biopharmaceutical sector.

3. Toralgen

• Website: toralgen.com
• Ownership type: Venture Capital
• Headquarters: Indianapolis, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: Seed, $8.3M, December 2020
• Founded year: 2017
• Headcount: 1-10
• LinkedIn: toralgen

Toralgen, founded in 2017 and based in Indianapolis, Indiana, is a biotechnology company dedicated to advancing drug delivery systems. The firm specializes in a unique poly-bile nanoparticle platform designed to improve the oral delivery of biologics, which can enhance patient compliance and overall treatment experience. Currently, Toralgen is focused on developing therapies for diabetes and autoimmune disorders, collaborating with pharmaceutical partners to create novel formulations. The company has successfully raised $8.3 million in seed funding, which supports its research and development efforts. With a team that boasts over 150 years of combined experience in pharmaceutical research and development, Toralgen is positioned to make a significant impact in the biopharmaceutical industry, particularly in the area of oral drug delivery. Their technology has been recognized in the industry, including being named a top startup by StartUs Insights and gaining acceptance into the FDA's Emerging Technology Program.

4. Gate Neurosciences

• Website: gateneuro.com
• Ownership type: Venture Capital
• Headquarters: Indianapolis, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: $25.0M, October 2022
• Founded year: 2019
• Headcount: 11-50
• LinkedIn: gate-neurosciences-inc

Gate Neurosciences, founded in 2019 and based in Indianapolis, Indiana, is a biotechnology company dedicated to developing innovative therapies for neuropsychiatric and cognitive disorders. The company employs precision medicine to enhance synaptic function, targeting the needs of patients suffering from conditions such as major depressive disorder. Their clinical-stage pipeline includes several promising drug candidates, including Zelquistinel, which is currently in Phase 2 development. Gate Neurosciences has received $25 million in funding, which underscores their commitment to advancing research in mental health. The company is actively engaged in addressing the challenges of central nervous system disorders, aiming to provide new treatment options for patients in need.

5. Waterstone Pharmaceuticals, Inc.

• Website: waterstonepharma.com
• Ownership type: Venture Capital
• Headquarters: Carmel, Indiana, United States (USA)
• Employee distribution: China 100%
• Latest funding: Other (Debt), $19.0M, September 2012
• Founded year: 2008
• Headcount: 501-1000
• LinkedIn: waterstone-pharmaceuticals-inc.

Waterstone Pharmaceuticals, Inc. is a Carmel, Indiana-based pharmaceutical company founded in 2008. The firm specializes in the research and production of medications aimed at treating metabolic diseases, with a particular emphasis on diabetes and kidney disease. Waterstone serves healthcare providers and pharmaceutical businesses by providing innovative drug solutions and high-quality pharmaceutical products. The company is involved in both drug development and manufacturing, focusing on high molecular polymer drug intermediates. Notably, Waterstone has received $19 million in funding, which reflects its growth potential and the confidence investors have in its business model. The company operates primarily in China, indicating a strategic focus on international markets and collaborations.

6. Inotiv

• Website: inotiv.com
• Ownership type: Private
• Headquarters: West Lafayette, Indiana, United States (USA)
• Employee distribution: United States (USA) 96%, United Kingdom (UK) 2%, Other 2%
• Founded year: 1974
• Headcount: 1001-5000
• LinkedIn: inotiv

Inotiv, based in West Lafayette, Indiana, is a contract research organization that specializes in life sciences. Founded in 1974, the company has built a reputation for providing a wide array of services that are critical to the pharmaceutical and biotech industries. Inotiv offers expertise in drug metabolism, pharmacokinetics, toxicology assessments, and research models, which are essential for clients aiming to navigate the intricate processes of drug discovery and development. Their services cater to a variety of therapeutic areas, including oncology, neuroscience, and infectious diseases, among others. Inotiv collaborates with pharmaceutical companies, government agencies, and academic institutions, ensuring that they meet the rigorous demands of drug development. With a workforce of approximately 1,757 employees, Inotiv is well-positioned to support clients through various research phases, from discovery to pre-marketing authorization.

7. Genezen

• Website: genezen.com
• Ownership type: Private Equity
• Headquarters: Indianapolis, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: $18.5M, November 2023
• Founded year: 2014
• Headcount: 51-200
• LinkedIn: genezen-laboratories

Genezen, founded in 2014 and based in Indianapolis, Indiana, is a biotechnology firm that specializes in gene and cell therapy manufacturing solutions. The company provides contract development and manufacturing services, focusing on viral vector production and testing for biotechnology and pharmaceutical clients. Genezen's expertise spans the entire process from plasmid design to commercial manufacturing, helping to accelerate the development of advanced therapies. Their state-of-the-art facility is designed for the aseptic manufacture of various viral vectors, including lentivirus, retrovirus, and adeno-associated virus. Genezen has recently secured $18.5 million in funding, reflecting their growth and commitment to enhancing their manufacturing capabilities. The company emphasizes a quality-first approach, ensuring compliance with stringent regulatory standards, which is crucial for the success of gene and cell therapies.

8. Quantigen Biosciences

• Website: quantigen.com
• Ownership type: Corporate
• Headquarters: Fishers, Indiana, United States (USA)
• Latest funding: July 2023
• Founded year: 2009
• Headcount: 11-50
• LinkedIn: quantigen-genomic-services

Quantigen Biosciences, founded in 2009 and based in Fishers, Indiana, is a biotechnology company that specializes in clinical diagnostics and research services. The company offers a range of solutions, including biomarker development, clinical trials support, and infectious disease testing. Quantigen's clientele includes pharmaceutical companies and healthcare organizations that depend on its expertise to improve research outcomes and patient care. Recently, Quantigen became part of Versiti, a national leader in blood health innovation, which enhances its capabilities in clinical and translational research. The company is certified by the Centers for Medicare and Medicaid Services and accredited through the College of American Pathologists, demonstrating its commitment to high-quality standards in laboratory practices. Quantigen's work in infectious disease testing and its collaborations with organizations like the Bill and Melinda Gates Foundation highlight its role in addressing global health challenges.

9. B2S Life Sciences

• Website: b2slifesciences.com
• Ownership type: Private
• Headquarters: Franklin, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2014
• Headcount: 11-50
• LinkedIn: b2slifesciences

B2S Life Sciences, founded in 2014 and based in Franklin, Indiana, is a biotechnology company dedicated to enhancing biotherapeutic development. The firm specializes in providing custom reagent products and services tailored to the needs of clients in the pharmaceutical and biotechnology sectors. Their offerings include assay development, life cycle management, and data analytics, which are crucial for ensuring compliance and efficiency in the drug development process. B2S Life Sciences operates as a contract research organization (CRO) and is recognized for its expertise in bioanalytical methods and statistical analysis. The company supports clients from late-phase discovery through to regulatory submissions, making it a key player in the biopharmaceutical industry. With a team of experienced professionals, B2S Life Sciences aims to maximize research and development quality, ultimately facilitating successful regulatory submissions for biotherapeutic products.

10. MediSphere Medical Research Center, LLC

• Website: medisphereresearch.com
• Ownership type: Private
• Headquarters: Evansville, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1992
• Headcount: 11-50
• LinkedIn: medisphere-medical-research-center-llc

MediSphere Medical Research Center, LLC, based in Evansville, Indiana, has been operational since 1992. This private clinical research center specializes in conducting medical studies and trials aimed at assessing new treatments and medications. With a dedicated team of professionals, MediSphere has successfully completed over 900 studies, collaborating closely with pharmaceutical companies in various phases of drug development. Their research covers a range of health issues, including diabetic gastroparesis, high cholesterol with cardiovascular disease, and chronic kidney disease. MediSphere is committed to providing safe and regulated trials, monitored by independent review boards, ensuring that participants receive comprehensive care while contributing to the advancement of medical science. They also engage with the community, promoting awareness and participation in clinical research, which further solidifies their role in the biopharmaceutical industry.

11. ParaPRO, LLC

• Website: parapro.com
• Ownership type: Private
• Headquarters: Carmel, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2002
• Headcount: 51-200
• LinkedIn: parapro-llc

ParaPRO, LLC, founded in 2002 and based in Carmel, Indiana, is a specialty pharmaceutical company dedicated to developing and commercializing therapies for parasitic infestations. The company has a strong focus on addressing public health concerns associated with head lice and scabies, conditions that affect millions of people annually. Their primary product, Natroba™ (spinosad) Topical Suspension, received FDA approval in 2011 and has since become the most prescribed medication for head lice. ParaPRO's commitment to innovation is evident in their use of spinosad, a naturally occurring compound that minimizes treatment failures and resistance issues commonly seen with other treatments. The company collaborates with healthcare professionals and organizations to enhance awareness and improve treatment outcomes for affected families.

12. Baxter Pharmaceutical Solutions LLC.

• Website: baxterbiopharmasolutions.com
• Ownership type: Private
• Headquarters: Bloomington, Indiana, United States (USA)
• Founded year: 1931
• Headcount: 1001-5000
• LinkedIn: indiana-metal-craft

Baxter Pharmaceutical Solutions LLC, also known as Simtra BioPharma Solutions, is a contract development and manufacturing organization based in Bloomington, Indiana. Founded in 1931, the company has built a strong reputation in the pharmaceutical and biopharmaceutical sectors. They specialize in providing a range of services tailored to the needs of pharmaceutical companies, focusing on sterile injectable products. Their offerings include formulation development, lyophilization cycle optimization, and fill/finish operations, which are crucial for ensuring the safety and efficacy of injectable medications. With facilities in both the United States and Germany, Baxter adheres to stringent cGMP standards and ISO certifications, ensuring high-quality production processes. The company has received multiple industry awards for its manufacturing excellence, reflecting its commitment to operational quality and customer service. Their expertise in handling complex drug formulations, including biologics and cytotoxics, positions them as a valuable partner for pharmaceutical companies looking to navigate the complexities of drug development and commercialization.

13. Pearl Pathways

• Website: pearlpathways.com
• Ownership type: Private
• Headquarters: Indianapolis, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2010
• Headcount: 11-50
• LinkedIn: pearl-pathways

Pearl Pathways is a consulting firm based in Indianapolis, Indiana, founded in 2010. The company specializes in providing life sciences product development services, focusing on regulatory, quality compliance, and clinical services. They cater to biopharmaceutical, medical device, and diagnostic companies, assisting them in navigating the intricate regulatory landscape and ensuring compliance throughout the product development process. Pearl Pathways is recognized for its expertise in accelerating the development of life-saving therapeutics and devices. Their team comprises experienced professionals who collaborate closely with clients to deliver tailored solutions that meet specific needs. The firm also operates a fully accredited Independent Review Board (IRB), which underscores its commitment to ethical standards in human research. Pearl Pathways has established itself as a trusted partner for both emerging and established companies in the life sciences sector, helping them bring innovative products to market efficiently.

14. Exelead

• Website: exeleadbiopharma.com
• Ownership type: Corporate
• Headquarters: Indianapolis, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: $780.0M, January 2022
• Founded year: 2017
• Headcount: 201-500
• LinkedIn: exelead

Exelead, founded in 2017 and based in Indianapolis, Indiana, is a contract pharmaceutical manufacturer that specializes in the production of lipid nanoparticles, liposomes, and pegylation formulations. The company provides comprehensive contract manufacturing services, supporting pharmaceutical and biotech companies in navigating the complexities of drug development. Their offerings span from preclinical development, including formulation and analytical method development, to clinical supply and commercial contract manufacturing. Exelead's facilities are equipped to handle both small and large batch sizes, catering to a range of client needs. The company has established itself as a partner for clients at various stages of drug development, emphasizing quality control and regulatory compliance. In January 2022, Exelead secured $780 million in funding, reflecting strong market confidence in their capabilities and growth potential. Their focus on innovative drug delivery systems positions them as a significant player in the biopharmaceutical industry.

15. SpectronRx

• Website: spectronrx.com
• Ownership type: Private
• Headquarters: Indianapolis, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2004
• Headcount: 51-200
• LinkedIn: spectronrx

SpectronRx, founded in 2004 and based in Indianapolis, Indiana, is a private pharmaceutical company that specializes in radiopharmaceuticals and contract development services. The company provides comprehensive solutions for drug development, regulatory assistance, and isotope procurement, primarily serving pharmaceutical companies and research organizations. With a team of experts, including multiple PhDs in radiochemistry, SpectronRx ensures compliance with regulatory standards and facilitates the timely delivery of critical medical products. Their services include advanced development and labeling of molecules, worldwide logistics, and regulatory consulting, making them a valuable partner in the drug development process. The company operates multiple facilities and has a strong focus on the growing field of theranostics, which combines diagnostics and therapeutics. SpectronRx's commitment to quality and patient care is evident in their operations and the expertise of their leadership team, which has extensive experience in the medical isotope industry.

16. INCOG BioPharma Services

• Website: incogbiopharma.com
• Ownership type: Venture Capital
• Headquarters: Fishers, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: Series B, $42.9M, May 2024
• Founded year: 2020
• Headcount: 201-500
• LinkedIn: incog-biopharma

INCOG BioPharma Services, based in Fishers, Indiana, is a contract development and manufacturing organization (CDMO) that focuses on the biopharmaceutical industry. Established in 2020, the company offers a range of services including formulation, filling, and quality control for injectable drug products. INCOG aims to support biopharmaceutical companies by providing reliable and efficient solutions to navigate the complexities of drug development. Their state-of-the-art facilities and commitment to quality ensure that they can meet the rigorous demands of the industry. Recently, INCOG secured $42.86 million in Series B funding, which underscores their growth potential and the confidence investors have in their business model. With a team that boasts extensive experience in the CDMO sector, INCOG is well-positioned to help clients bring life-saving drugs to market more effectively.

17. Formulary Insights-Powered by Petauri

• Website: formularyinsights.com
• Ownership type: Corporate
• Headquarters: Indianapolis, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: November 2024
• Founded year: 2016
• Headcount: 11-50
• LinkedIn: formularyinsights

Formulary Insights-Powered by Petauri, based in Indianapolis, Indiana, is a market access consulting firm founded in 2016. With a team of experts boasting decades of experience in the biopharmaceutical and payer industries, the company provides critical research and insights to help biopharmaceutical manufacturers and investors navigate the complexities of the U.S. market access landscape. Their services include agile research methodologies and access to expert payer panels, which enable clients to make informed decisions regarding business development, pipeline development, launch planning, and product performance. By leveraging real-world insights from active market access decision-makers, Formulary Insights aims to enhance patient access to medications and improve the overall effectiveness of market strategies for their clients.

18. Concentrics Research, an IQVIA business

• Website: concentricsresearch.com
• Ownership type: Private
• Headquarters: Indianapolis, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1985
• Headcount: 51-200
• LinkedIn: concentrics-research

Concentrics Research, an IQVIA business, is a Contract Research Organization based in Indianapolis, Indiana, with a history dating back to 1985. The company specializes in late-stage clinical research and healthcare market research, providing essential services to pharmaceutical and biotechnology firms. Concentrics is particularly noted for its expertise in Rx-to-OTC Switch processes, having worked on a significant majority of successful drug switches in the market. Their services include consultation on FDA strategy, clinical trial management, and market research, all tailored to meet the specific needs of their clients. With a dedicated team of specialists, Concentrics aims to enhance the health and quality of life for consumers through innovative research solutions. The company operates from two locations, including a strategy center in Parsippany, New Jersey, which facilitates focused discussions and accelerated project timelines. Recently, Concentrics was acquired by IQVIA, further expanding its capabilities and global reach in the biopharmaceutical industry.

19. Singota Solutions

• Website: singota.com
• Ownership type: Private
• Headquarters: Bloomington, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2006
• Headcount: 51-200
• LinkedIn: singota-solutions

Singota Solutions, based in Bloomington, Indiana, is a contract development and manufacturing organization (CDMO) established in 2006. Originally founded as BioConvergence LLC, the company rebranded in 2016 to reflect its expanded capabilities in aseptic manufacturing and drug development services. Singota specializes in a range of services tailored to the pharmaceutical and biotechnology sectors, including drug formulation development, analytical testing, aseptic filling, and supply chain management. Their expertise in small batch aseptic filling and cold chain pharmaceutical storage is particularly relevant for early-phase development projects. Singota's commitment to quality is evident in their use of advanced technologies, such as the robotic SA25 Aseptic Filling system, which has helped maintain a strong sterility record. The company operates with a focus on collaboration and transparency, ensuring that clients receive tailored solutions to meet their specific needs throughout the drug development pipeline.

20. Sentry BioPharma Services, Inc.

• Website: sentrybps.com
• Ownership type: Private
• Headquarters: Indianapolis, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2006
• Headcount: 51-200
• LinkedIn: sentry-biopharma-services-inc-

Sentry BioPharma Services, Inc., founded in 2006 and based in Indianapolis, Indiana, is a private company that provides essential services to the biopharmaceutical sector. The firm specializes in pharmaceutical storage, distribution, and packaging, with a strong emphasis on controlled temperature management. Sentry caters to the needs of biotech and pharmaceutical companies, ensuring the integrity of temperature-sensitive products throughout the supply chain. Their services include quality assurance, regulatory compliance, and support for clinical trials. Sentry operates a cGMP compliant facility and is accredited by the NABP, which underscores their commitment to maintaining high standards in the handling of pharmaceuticals. The company has established a global footprint, serving clients across multiple countries and time zones, and has successfully managed over 40,000 shipments. Their focus on custom solutions and advanced security measures for controlled substances further highlights their expertise in navigating the complexities of the biopharmaceutical industry.

21. Greenfield Pathology Services, Inc.

• Website: gfpath.com
• Ownership type: Private
• Headquarters: Greenfield, Indiana, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2019
• Headcount: 11-50
• LinkedIn: greenfield-pathology-services-inc

Greenfield Pathology Services, Inc., founded in 2019 and based in Greenfield, Indiana, is a consulting company that specializes in toxicologic pathology. With a team of experienced pathologists, the firm offers a range of services including pathology evaluations, peer reviews, and expert consulting. Their expertise supports clients in the pharmaceutical and biotechnology sectors, particularly in drug development and ensuring compliance with regulatory standards. The staff at Greenfield Pathology Services boasts an average of over 20 years of experience in toxicologic pathology, having worked in both pharmaceutical companies and contract research organizations (CROs). This extensive background allows them to provide valuable insights and guidance throughout the drug development process, from initial discovery to regulatory submissions.

Biopharmaceutical Companies Insights: Key Companies in Indiana

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