California is home to a thriving healthcare software industry that supports a wide array of solutions aimed at improving patient care and operational efficiency. The sector primarily consists of companies offering electronic health record (EHR) platforms, telehealth services, patient engagement tools, and data analytics. As healthcare continues to digitize, these companies are merging technology with medical expertise, positioning themselves at the forefront of the rapidly evolving landscape. Insights suggest that AI integration and an emphasis on interoperability are defining the future, enhancing decision-making and streamlining workflows across the medical field.

The companies listed range from small startups to larger firms, with workforces varying from less than 100 to over 5,000 employees. Most of these companies are headquartered in California's tech hubs like San Francisco and Palo Alto, having been founded from 1996 to 2017. They specialize in key areas such as electronic health records, patient engagement solutions, and practice management software, reflecting a robust blend of innovation and practical application in healthcare.

Continue reading to explore the top healthcare software companies in California.

Top 20 Healthcare Software Companies in California

1. Innovaccer

• Website: innovaccer.com
• Ownership type: Venture Capital
• Headquarters: San Francisco, California, United States (USA)
• Employee distribution: India 87%, United States (USA) 13%
• Latest funding: January 2025
• Founded year: 2014
• Headcount: 1001-5000
• LinkedIn: innovaccer

Innovaccer Inc., founded in 2014 and based in San Francisco, California, is a healthcare technology firm that specializes in providing a comprehensive data activation platform and advanced analytics solutions. The company serves a wide range of clients, including healthcare providers, payers, and life sciences organizations. Innovaccer's primary goal is to enhance patient care and operational efficiency through data-driven decision-making. Their Health Cloud platform unifies healthcare data, enabling organizations to improve clinical and financial outcomes. Innovaccer has made significant strides in the industry, helping over 96,000 healthcare professionals and unifying more than 54 million patient records. The company has also been recognized for its contributions to value-based care and has received accolades for its innovative solutions. With a workforce of over 1,500 employees, primarily based in India and the United States, Innovaccer continues to expand its influence in the healthcare technology space.

2. Practice Fusion from Veradigm

• Website: practicefusion.com
• Ownership type: Corporate
• Headquarters: San Francisco, California, United States (USA)
• Employee distribution: United States (USA) 92%, India 4%, Indonesia 4%
• Latest funding: $100.0M, January 2018
• Founded year: 2005
• Headcount: 201-500
• LinkedIn: practice-fusion

Practice Fusion from Veradigm is a healthcare technology company based in San Francisco, California, founded in 2005. The company specializes in a cloud-based electronic health record (EHR) platform designed specifically for independent medical practices. Their offerings include a range of services such as customizable charting, electronic prescribing, and patient engagement solutions, all aimed at improving the efficiency of healthcare delivery. With a workforce of approximately 102 employees, Practice Fusion has built a reputation for being responsive to user feedback and addressing the needs of small to medium-sized practices. The platform is utilized by around 30,000 medical practices, facilitating approximately 5 million patient visits each month. This extensive usage underscores their significant role in the healthcare software industry, particularly for practices seeking to streamline operations and enhance patient care.

3. TigerConnect

• Website: tigerconnect.com
• Ownership type: Private Equity
• Headquarters: Santa Monica, California, United States (USA)
• Employee distribution: United States (USA) 65%, Mexico 26%, China 7%, Other 2%
• Latest funding: January 2022
• Founded year: 2010
• Headcount: 201-500
• LinkedIn: tigerconnect

TigerConnect, founded in 2010 and based in Santa Monica, California, is a healthcare communication software provider dedicated to improving clinical collaboration and streamlining workflows for healthcare organizations. The company offers a suite of products designed to enhance patient care and operational efficiency, including a Clinical Collaboration Platform, Alarm Management, Patient Engagement, and Physician Scheduling. TigerConnect serves a wide range of clients, including hospitals, physician groups, and home health agencies. Their solutions are designed to facilitate secure communication among healthcare professionals, ultimately leading to better patient outcomes. With a workforce of approximately 308 employees and a strong presence in the market, TigerConnect has established itself as a significant player in the healthcare software industry, focusing on the critical need for effective communication in clinical settings.

4. MD Synergy Solutions, LLC

• Website: mdsynergy.com
• Ownership type: Venture Capital
• Headquarters: Calabasas, California, United States (USA)
• Employee distribution: India 56%, United States (USA) 44%
• Latest funding: Seed, $800,000, January 2013
• Founded year: 2000
• Headcount: 51-200
• LinkedIn: md-synergy

MD Synergy Solutions, LLC, based in Calabasas, California, is a healthcare technology firm that focuses on providing electronic health record (EHR) systems and practice management solutions. Founded in 2000, the company has developed products like Althea Smart EHR, which aims to streamline patient management and documentation processes for healthcare providers. Their offerings include features such as telemedicine, patient portals, and integrated billing solutions, all designed to enhance operational efficiency in medical practices. With a workforce of around 62 employees, MD Synergy has a significant presence in the healthcare software industry. The company has also secured funding, with a notable seed investment of $800,000 in 2013, reflecting a commitment to innovation and growth in the healthcare technology space.

5. Meditab Software Inc.

• Website: meditab.com
• Ownership type: Family Owned
• Headquarters: Sacramento, California, United States (USA)
• Employee distribution: India 90%, United States (USA) 7%, Philippines 2%
• Founded year: 1998
• Headcount: 201-500
• LinkedIn: meditab-software-inc-

Meditab Software Inc., based in Sacramento, California, is a family-owned healthcare software provider that specializes in electronic health records (EHR) and practice management solutions. Founded in 1998, the company was born out of a desire to address the frustrations experienced by healthcare providers with existing software. Meditab offers a comprehensive suite of products designed to streamline operations for medical practices, including features for patient engagement, billing, and telemedicine. Their flagship product, Intelligent Medical Software (IMS), integrates various aspects of practice management into a single platform, catering to over 40 medical specialties. Meditab has built a reputation for its commitment to innovation, continuously evolving its technology to meet the changing demands of the healthcare industry. The company also provides extensive support services, including 24/7 customer assistance and educational resources for healthcare providers. With a significant portion of its workforce located in India, Meditab has positioned itself as a global player in the healthcare software market, serving thousands of healthcare professionals across the United States and beyond.

6. Glooko

• Website: glooko.com
• Ownership type: Venture Capital
• Headquarters: Palo Alto, California, United States (USA)
• Employee distribution: United States (USA) 39%, Sweden 36%, Croatia 15%, Other 10%
• Latest funding: Series E-K, $100.0M, October 2024
• Founded year: 2010
• Headcount: 51-200
• LinkedIn: glooko

Glooko, Inc. is a healthcare technology company based in Palo Alto, California, founded in 2010. The company provides a Software-as-a-Service (SaaS) platform designed specifically for diabetes management. Glooko's platform allows patients to track their health data, while healthcare providers can monitor and manage patient care remotely. With operations in over 30 countries and partnerships with more than 10,000 clinics globally, Glooko serves both consumers and healthcare professionals. The company has integrated over 200 devices into its platform, enhancing its utility for users. Recently, Glooko secured $100 million in Series F funding, which will support its mission to transform diabetes care and improve health outcomes for patients. Their commitment to innovation is evident in their ongoing clinical trials and partnerships with life sciences organizations, aiming to leverage real-world data to enhance chronic condition management.

7. Zynx Health

• Website: zynxhealth.com
• Ownership type: Corporate
• Headquarters: South San Francisco, California, United States (USA)
• Employee distribution: United States (USA) 96%, India 4%
• Latest funding: March 2004
• Founded year: 1996
• Headcount: 51-200
• LinkedIn: zynx-health

Zynx Health, based in South San Francisco, California, is a healthcare technology company that specializes in evidence-based clinical decision support solutions. Founded in 1996 by clinicians at Cedars-Sinai Medical Center, Zynx Health has dedicated itself to improving patient care through innovative software tools. Their offerings include care management tools, analytics, and solutions tailored for primary care and chronic care management. The company has a strong focus on empowering healthcare organizations to enhance their clinical practices and operational efficiency. Zynx Health has received recognition in the industry, including multiple Best in KLAS awards, which highlight their effectiveness in delivering quality care solutions. With a workforce of around 100 employees, the company continues to support thousands of healthcare organizations in aligning their strategies with evidence-based best practices.

8. Luma Health

• Website: lumahealth.io
• Ownership type: Venture Capital
• Headquarters: San Mateo, California, United States (USA)
• Employee distribution: United States (USA) 90%, Brazil 8%, Other 2%
• Latest funding: Series C, $130.0M, November 2021
• Founded year: 2015
• Headcount: 51-200
• LinkedIn: lumahealth

Luma Health, based in San Mateo, California, is a healthcare technology company that specializes in patient engagement solutions. Established in 2015, the company offers a Patient Success Platform that aims to enhance patient access and streamline healthcare processes. Their platform includes features such as automated scheduling, patient communication, eligibility verification, and feedback management, all designed to improve operational efficiency for healthcare organizations. Luma Health has successfully integrated with major electronic health record (EHR) systems, allowing for seamless workflows that reduce manual tasks for staff. The company has gained traction in the industry, serving over 650 healthcare organizations nationwide. In November 2021, Luma Health raised $130 million in a Series C funding round, reflecting strong investor interest and confidence in their innovative approach to healthcare technology.

9. Compulink Healthcare Solutions

• Website: compulinkadvantage.com
• Ownership type: Private
• Headquarters: Thousand Oaks, California, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1985
• Headcount: 201-500
• LinkedIn: compulink-healthcare-solutions

Compulink Healthcare Solutions, based in Thousand Oaks, California, is a private company that has been providing healthcare software solutions since 1985. The firm specializes in electronic health records (EHR) and practice management systems tailored to various medical specialties. Their software solutions are designed to streamline operations, enhance patient engagement, and improve revenue management for healthcare providers. Compulink serves a wide range of medical practices and clinics, offering tools that include telehealth services, revenue cycle management, and patient engagement features. The company emphasizes customization and efficiency, aiming to reduce administrative burdens and improve patient care outcomes. Compulink's focus on specialty-specific EHR systems allows them to address the unique needs of different medical fields, making them a relevant player in the healthcare technology sector.

10. CharmHealth

• Website: charmhealth.com
• Ownership type: Private
• Headquarters: Pleasanton, California, United States (USA)
• Employee distribution: United States (USA) 67%, India 33%
• Founded year: 2007
• Headcount: 51-200
• LinkedIn: charm-ehr

CharmHealth, founded in 2007 and based in Pleasanton, California, is a private healthcare technology firm that specializes in cloud-based solutions for electronic health records (EHR), practice management, and patient engagement. The company serves a variety of healthcare providers, including clinics and hospitals, with a focus on enhancing operational efficiency and patient care. CharmHealth's platform is designed to be customizable and scalable, catering to the needs of both small practices and larger enterprises. Their services include practice onboarding, online training, and EMR migration, which support healthcare providers in transitioning to digital solutions. The company has a significant presence in the U.S. and India, with a workforce that reflects this distribution. CharmHealth's commitment to innovation is evident in their offerings, which include telehealth services and a robust patient engagement platform, aligning with the growing demand for digital health solutions.

11. HealthFusion Inc.

• Website: healthfusion.com
• Ownership type: Corporate
• Headquarters: Solana Beach, California, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: $165.0M, October 2015
• Founded year: 1998
• Headcount: 51-200
• LinkedIn: healthfusion-inc

HealthFusion Inc., known as NextGen Healthcare, is a healthcare technology provider based in Solana Beach, California. Founded in 1998, the company specializes in delivering software solutions tailored for ambulatory medical practices. Their offerings include Electronic Health Records (EHR), practice management systems, telehealth services, and revenue cycle management. HealthFusion aims to enhance patient care and operational efficiency for healthcare providers. The company has received significant funding, totaling $165 million, which underscores investor confidence in their business model and growth potential. With a dedicated focus on improving the healthcare experience for both providers and patients, HealthFusion continues to play a vital role in the healthcare software industry.

12. PipelineRx

• Website: pipelinerx.com
• Ownership type: Venture Capital
• Headquarters: San Francisco, California, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: $15.4M, October 2017
• Founded year: 2009
• Headcount: 51-200
• LinkedIn: pipelinerx

PipelineRx, founded in 2009 and based in San Francisco, California, is a healthcare service provider that specializes in pharmacy management and clinical services. The company offers a range of solutions designed to enhance patient care and operational efficiency, including telepharmacy services, patient therapy management, and antimicrobial stewardship programs. PipelineRx serves community hospitals, health systems, and specialized facilities, integrating pharmacists into care teams to optimize medication management and improve patient outcomes. With a workforce of approximately 166 employees, the company has demonstrated its commitment to advancing clinical programs through technology and innovative practices. In 2017, PipelineRx secured funding of over $15 million, reflecting investor confidence in its business model and growth potential.

13. Med Tech Solutions

• Website: medtechsolutions.com
• Ownership type: Venture Capital
• Headquarters: Santa Clarita, California, United States (USA)
• Employee distribution: United States (USA) 97%, India 3%
• Latest funding: May 2020
• Founded year: 2006
• Headcount: 201-500
• LinkedIn: mts-healthcare

Med Tech Solutions, founded in 2006 and based in Santa Clarita, California, is a healthcare IT services company that focuses on providing tailored cloud services, software solutions, and managed services for healthcare organizations. With a workforce of around 128 employees, the company supports a variety of healthcare clients, including clinics, hospitals, and community health centers. Their services include managing electronic health records (EHR), ensuring security and compliance, and optimizing operational efficiency. Med Tech Solutions has developed a reputation for its expertise in EHR hosting and integration, as well as its commitment to maintaining high standards of data security and compliance with regulations such as HIPAA. The company has not reported any recent funding, indicating a stable operational model since its last funding round in 2020. Their focus on healthcare IT positions them as a significant player in the industry, dedicated to enhancing the technological capabilities of healthcare providers.

14. 314e Corporation

• Website: 314e.com
• Ownership type: Private
• Headquarters: Dublin, California, United States (USA)
• Employee distribution: India 71%, United States (USA) 22%, Bhutan 6%
• Founded year: 2004
• Headcount: 501-1000
• LinkedIn: 314e-corporation

314e Corporation, founded in 2004 and based in Dublin, California, is a private healthcare IT solutions provider. The company specializes in AI-driven products and consulting services aimed at hospitals and health systems. Their product lineup includes the Jeeves training platform for EHR users, the Dexit document management system, and the Muspell Archive for data archiving, among others. 314e serves a variety of clients, including enterprise customers and academic medical centers, focusing on enhancing operational efficiency and patient engagement. Their consulting services cover areas such as Epic EHR support, healthcare data analytics, and revenue cycle management, showcasing their comprehensive approach to healthcare IT challenges. With a significant portion of their workforce located in India, they leverage global talent to deliver their services effectively.

15. Suki

• Website: suki.ai
• Ownership type: Venture Capital
• Headquarters: Redwood City, California, United States (USA)
• Employee distribution: India 53%, United States (USA) 45%, Other 1%
• Latest funding: January 2025
• Founded year: 2017
• Headcount: 201-500
• LinkedIn: sukihq

Suki is a healthcare technology firm based in Redwood City, California, founded in 2017. The company specializes in AI-driven solutions aimed at improving clinical documentation and integrating with electronic health records (EHR). Its primary products, Suki Assistant and Suki Compose, are designed to streamline administrative tasks for healthcare professionals, thereby reducing burnout and enhancing patient care. Suki's technology is particularly notable for its deep integration capabilities with major EHR systems such as Epic, Cerner, Athena, and Meditech. This integration allows clinicians to generate notes and manage documentation more efficiently, which is crucial in today's fast-paced healthcare environment. Suki has garnered attention for its innovative approach and has received recognition in various industry awards, highlighting its impact on healthcare technology.

16. ChiroTouch

• Website: chirotouch.com
• Ownership type: Private Equity
• Headquarters: San Diego, California, United States (USA)
• Employee distribution: United States (USA) 98%, Malaysia 2%
• Latest funding: July 2017
• Founded year: 2009
• Headcount: 51-200
• LinkedIn: chirotouch

ChiroTouch, founded in 2009 and based in San Diego, California, is a healthcare technology company that specializes in software solutions tailored for chiropractic practices. With a workforce of approximately 191 employees, ChiroTouch provides a comprehensive suite of tools designed to streamline operations for chiropractic clinics. Their offerings include practice management software, billing solutions, and patient engagement tools, which help chiropractors enhance patient care and improve operational efficiency. The company has developed its software based on insights from over 36,000 chiropractic providers, ensuring that their solutions meet the specific needs of the industry. ChiroTouch has not reported any recent funding, indicating a stable operational model since its last funding round in 2017. Their focus on cloud-based solutions and integrated services positions them as a relevant player in the healthcare software sector, particularly for practices that prioritize patient management and billing efficiency.

17. SPsoft

• Website: spsoft.com
• Ownership type: Private
• Headquarters: San Mateo, California, United States (USA)
• Employee distribution: Ukraine 64%, United States (USA) 14%, Germany 7%, Other 14%
• Founded year: 2017
• Headcount: 51-200
• LinkedIn: spsoft-com

SPsoft, founded in 2017 and based in San Mateo, California, is a private healthcare software development company. With a team of approximately 42 employees, the company focuses on delivering custom software solutions specifically designed for healthcare providers. Their services include mobile app development, data analytics, and cloud enablement, all aimed at improving patient engagement and operational efficiency. SPsoft has worked with various healthcare organizations to enhance their digital infrastructure, successfully delivering over 20 healthcare software solutions that serve more than 500,000 patients. The company emphasizes compliance with healthcare standards, including HIPAA and FHIR, ensuring that their solutions meet the necessary regulatory requirements. Their expertise in areas such as AI, machine learning, and data analytics further positions them as a relevant player in the healthcare software industry.

18. Marina Medical Billing Service Inc

• Website: tsystem.com
• Ownership type: Corporate
• Headquarters: Cerritos, California, United States (USA)
• Latest funding: $200.0M, September 2017
• Founded year: 1981
• Headcount: 201-500
• LinkedIn: marina-medical-billing-service-inc

Marina Medical Billing Service Inc, known as The T System, is a healthcare technology company based in Cerritos, California. Founded in 1981, the company has carved out a niche in providing documentation solutions specifically for emergency and urgent care settings. Their flagship products, including EV™ and T Sheets®, are designed to facilitate efficient clinical documentation and coding, addressing the unique challenges faced by healthcare providers in high-pressure environments. The T System's software is utilized by over 1,900 emergency care facilities across the United States, showcasing its widespread adoption and impact on the industry. The company is committed to enhancing patient care and operational efficiency through its innovative technology solutions. In 2017, The T System secured a substantial funding amount of $200 million, reflecting investor confidence in its business model and growth potential. This financial backing supports their ongoing development and enhancement of healthcare software solutions, ensuring they remain relevant in a rapidly evolving industry.

19. Episource

• Website: episource.com
• Ownership type: Private
• Headquarters: Gardena, California, United States (USA)
• Employee distribution: India 82%, United States (USA) 18%
• Founded year: 2006
• Headcount: 5001-10000
• LinkedIn: episourcellc

Episource, founded in 2006 and based in Gardena, California, is a healthcare consulting company that specializes in risk adjustment and quality improvement services. The firm offers a range of solutions tailored for healthcare payers and providers, including advanced analytics, medical record retrieval, and coding services. With a workforce of over 3,391 employees, a significant portion of whom are based in India, Episource leverages technology and expert teams to enhance patient outcomes and streamline operations. Their proprietary Episource Clarity Platform addresses key stages of the risk adjustment continuum, utilizing AI and natural language processing to improve efficiency and accuracy in coding and data management. The company has established a strong reputation for client retention and satisfaction, indicating their effectiveness in delivering value-driven solutions in the healthcare sector.

20. CliniComp

• Website: clinicomp.com
• Ownership type: Private
• Headquarters: San Diego, California, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1983
• Headcount: 51-200
• LinkedIn: clinicomp-intl-

CliniComp is a healthcare technology company based in San Diego, California, specializing in electronic health record (EHR) solutions and ancillary systems. Established in 1983, CliniComp has been at the forefront of healthcare IT, providing a comprehensive suite of services that includes clinical documentation, revenue cycle management, and advanced analytics tailored to the needs of hospitals and healthcare providers. The company prides itself on its innovative, scalable IT solutions that enhance patient care and streamline healthcare operations. CliniComp's System as a Service model offers a fixed-cost approach, integrating software, hardware, and services into a single package, which helps healthcare organizations manage costs effectively. With a commitment to customer support and a focus on continuous improvement, CliniComp has built a reputation for reliability and performance, serving a range of clients including private hospitals and government healthcare facilities. Their technology has been recognized for its effectiveness, and they have received accolades such as the MedTech Breakthrough Award for Best Electronic Health Record Service.

Healthcare Software Insights: Key Companies in California

Company	Headquarter	Size	Founded	Ownership
Innovaccer	San Francisco, California, United States (USA)	1001-5000	2014	Venture Capital
Practice Fusion from Veradigm	San Francisco, California, United States (USA)	201-500	2005	Corporate
TigerConnect	Santa Monica, California, United States (USA)	201-500	2010	Private Equity
MD Synergy Solutions, LLC	Calabasas, California, United States (USA)	51-200	2000	Venture Capital
Meditab Software Inc.	Sacramento, California, United States (USA)	201-500	1998	Family Owned
Glooko	Palo Alto, California, United States (USA)	51-200	2010	Venture Capital
Zynx Health	South San Francisco, California, United States (USA)	51-200	1996	Corporate
Luma Health	San Mateo, California, United States (USA)	51-200	2015	Venture Capital
Compulink Healthcare Solutions	Thousand Oaks, California, United States (USA)	201-500	1985	Private
CharmHealth	Pleasanton, California, United States (USA)	51-200	2007	Private
HealthFusion Inc.	Solana Beach, California, United States (USA)	51-200	1998	Corporate
PipelineRx	San Francisco, California, United States (USA)	51-200	2009	Venture Capital
Med Tech Solutions	Santa Clarita, California, United States (USA)	201-500	2006	Venture Capital
314e Corporation	Dublin, California, United States (USA)	501-1000	2004	Private
Suki	Redwood City, California, United States (USA)	201-500	2017	Venture Capital
ChiroTouch	San Diego, California, United States (USA)	51-200	2009	Private Equity
SPsoft	San Mateo, California, United States (USA)	51-200	2017	Private
Marina Medical Billing Service Inc	Cerritos, California, United States (USA)	201-500	1981	Corporate
Episource	Gardena, California, United States (USA)	5001-10000	2006	Private
CliniComp	San Diego, California, United States (USA)	51-200	1983	Private

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