California is home to a robust chemical manufacturing sector, which plays a crucial role in producing materials for various industries. This includes companies focused on biotechnology, sustainable products, and custom formulations. From specialty chemicals used in agricultural processes to advanced materials for electronic manufacturing, the state is renowned for its emphasis on innovation and sustainability. Amid rising environmental concerns, California's chemical industry is increasingly leaning towards green chemistry practices, showcasing a commitment to reducing carbon footprints and developing eco-friendly solutions that support both economy and ecology.

The following companies represent a spectrum of chemical manufacturing in California, varying in size from small firms to those with hundreds of employees. These firms are headquartered in key cities such as Los Angeles and San Diego and were founded between 1948 and 2016. They specialize in products ranging from biodegradable materials and industrial chemicals to advanced materials for energy efficiency and environmental sustainability.

Continue reading to learn about the top chemical manufacturing companies in California.

Top 20 Chemical Manufacturing Companies in California

1. Enviro Tech, an Arxada Company

• Website: envirotech.com
• Ownership type: Corporate
• Headquarters: Modesto, California, United States (USA)
• Employee distribution: United States (USA) 94%, India 6%
• Latest funding: December 2021
• Founded year: 1991
• Headcount: 201-500
• LinkedIn: enviro-tech-chemical-services

Enviro Tech, an Arxada Company, is a chemical manufacturer based in Modesto, California, specializing in the production of peracetic acid and stabilized bromine products. Founded in 1991, the company has carved out a niche in providing effective sanitation solutions across various sectors, including food safety, wastewater treatment, and agriculture. With manufacturing facilities located on both coasts of the United States, Enviro Tech is well-positioned to serve a broad customer base. The company emphasizes customer service and technical support, ensuring that clients receive the guidance needed to effectively utilize their products. Enviro Tech's product line includes over 500 items tailored for applications in meat and poultry processing, fruit and vegetable processing, and industrial water treatment, among others. Their innovative approach is highlighted by recent advancements, such as the introduction of the first dry peracetic acid sanitizer, showcasing their commitment to meeting industry needs while adhering to environmental standards.

2. Geno

• Website: genomatica.com
• Ownership type: Venture Capital
• Headquarters: San Diego, California, United States (USA)
• Employee distribution: United States (USA) 96%, Germany 2%, Canada 2%
• Latest funding: August 2021
• Founded year: 2000
• Headcount: 51-200
• LinkedIn: genomatica

Geno, officially known as Genomatica, is a biotechnology firm based in San Diego, California, founded in 2000. The company specializes in developing and licensing sustainable manufacturing processes for chemicals, focusing on creating plant-based alternatives to conventional materials. Their product portfolio includes plant-based nylon and butylene glycol, which cater to major brands in the personal care and textile sectors. Geno's innovative technologies aim to significantly reduce carbon emissions, with claims of up to 90% lower emissions compared to fossil fuel-based products. The company has established partnerships with notable brands, including lululemon, and has received recognition for its contributions to green chemistry. With a strong emphasis on sustainability, Geno is actively reshaping supply chains and promoting responsible sourcing in the chemical industry.

3. American Elements

• Website: americanelements.com
• Ownership type: Private
• Headquarters: Los Angeles, California, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1998
• Headcount: 201-500
• LinkedIn: american-elements

American Elements, founded in 1998 and based in Los Angeles, California, is a private company that operates as a materials supplier and chemical manufacturer. The firm specializes in a broad range of products, including elements, alloys, nanomaterials, and various chemicals. Their offerings cater to multiple industries, such as aerospace, automotive, and electronics, where they provide specialized materials essential for manufacturing and production processes. With a workforce of 201-500 employees, American Elements is dedicated to quality and innovation in materials science. They have established a global presence, serving clients across numerous sectors, and are known for their commitment to research and development in advanced materials. The company does not report any recent funding, indicating a stable operational model without external financial dependencies.

4. Eastar Chemical Corporation

• Website: eastarchem.com
• Ownership type: Private
• Headquarters: Sacramento, California, United States (USA)
• Employee distribution: United States (USA) 64%, India 36%
• Founded year: 1986
• Headcount: 201-500
• LinkedIn: eastar-chemical-corporation

Eastar Chemical Corporation, based in Sacramento, California, is a private chemical manufacturer and distributor that specializes in a wide array of specialty and fine chemicals. Established in 1986, the company has built a reputation for providing high-quality products and services tailored to the needs of its clients. Eastar offers a comprehensive suite of services, including sourcing, procurement, custom manufacturing, and logistics, which are essential for businesses in industries such as pharmaceuticals, personal care, and food products. Their product offerings include pharmaceutical intermediates, catalysts, and various chemical additives, demonstrating their involvement in critical sectors. With a workforce that spans the United States and India, Eastar is well-positioned to serve a global clientele, ensuring timely delivery and quality assurance. The company prides itself on its customer-centric approach, aiming to foster long-term partnerships with its clients.

5. Argo Chemical

• Website: argochem.com
• Ownership type: Private
• Headquarters: Bakersfield, California, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1980
• Headcount: 11-50
• LinkedIn: argo-chemical

Argo Chemical, based in Bakersfield, California, has been a key player in the chemical manufacturing sector since its inception in 1980. With a workforce of 11-50 employees, the company specializes in producing and supplying a variety of industrial chemical products. Their offerings include essential chemicals such as ammonium hydroxide, sodium hydroxide, and sulfuric acid, catering to industries like agriculture, water sanitation, food processing, and energy. Argo Chemical operates around the clock, ensuring that urgent chemical supply needs are met promptly. Their strategic location near major highways facilitates efficient distribution across California. The company prides itself on dependability and integrity, focusing on building trust with clients and providing tailored solutions to enhance operational efficiency. Argo Chemical's mission is to deliver high value in chemical product sales and technical services, reflecting their commitment to supporting the industries they serve.

6. Lygos

• Website: lygos.com
• Ownership type: Venture Capital
• Headquarters: Hayward, California, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: Convertible note, $160.0M, April 2022
• Founded year: 2011
• Headcount: 51-200
• LinkedIn: lygos

Lygos, founded in 2011 and based in Hayward, California, specializes in the production of bio-inspired materials aimed at creating sustainable solutions across multiple industries. The company operates in sectors such as agronomy, home care, personal care, and water treatment, providing products that enhance performance while meeting sustainability goals. Lygos is known for its Soltellus™ polymer, which is biodegradable and designed to improve crop yields and nutrient uptake in agriculture. In home care, their solutions help remove stains and enhance cleaning efficiency. The company has also developed products for water treatment that minimize environmental impact while maintaining effectiveness. With a workforce of around 79 employees and a recent funding round of $160 million in 2022, Lygos is positioned to expand its innovative offerings and strengthen its market presence.

7. Zymergen, Inc.

• Website: zymergen.com
• Ownership type: Corporate
• Headquarters: Emeryville, California, United States (USA)
• Latest funding: $300.0M, July 2022
• Founded year: 2013
• Headcount: 501-1000
• LinkedIn: zymergen-inc-

Zymergen, Inc., founded in 2013 and based in Emeryville, California, is a biotechnology firm that specializes in the intersection of genomics and machine learning. The company focuses on developing genetically modified organisms that can produce chemicals, catering to various industries including defense and large-scale manufacturing. Zymergen's innovative approach leverages advanced technologies to create solutions that enhance chemical production processes. The company has attracted significant investment, with a reported funding amount of $300 million as of July 2022, indicating strong investor confidence in its potential to impact the chemical manufacturing sector. Zymergen's work exemplifies the growing trend of integrating biotechnology into traditional chemical manufacturing, making it a noteworthy player in the industry.

8. Novvi, LLC

• Website: novvi.com
• Ownership type: Private
• Headquarters: Alameda, California, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: July 2016
• Founded year: 2003
• Headcount: 51-200
• LinkedIn: novvi-llc

Novvi, LLC, founded in 2003 and based in Alameda, California, is a private chemical manufacturer that specializes in sustainable materials. The company produces a variety of products, including lubricants, polymers, and materials specifically designed for electric vehicles. Novvi serves multiple industries, notably automotive and personal care, by offering high-performance alternatives to conventional petroleum-based products. Their approach emphasizes low-carbon solutions, helping clients achieve their sustainability objectives. With a manufacturing facility located in La Porte, Texas, Novvi utilizes bio-derived feedstocks and advanced chemical processing technologies to create renewable, high-performance chemicals. The company operates with a focus on environmental stewardship and aims to push the boundaries of product quality and performance in the chemical sector.

9. NuGenTec

• Website: nugentec.com
• Ownership type: Private
• Headquarters: Emeryville, California, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1997
• Headcount: 11-50
• LinkedIn: nugentec

NuGenTec, officially known as NuGeneration Technologies, is a specialty chemicals company based in Emeryville, California. Founded in 1997, the company has carved out a niche in providing eco-friendly cleaning products and industrial cleaners. Their product offerings are tailored for various industries, including biotechnology, pharmaceuticals, oil and gas, and electronics. NuGenTec operates manufacturing facilities in California, Texas, and Pennsylvania, allowing them to efficiently supply their products across the United States. The company emphasizes research and development to create safer alternatives to traditional hazardous chemicals, reflecting a growing trend towards sustainability in the chemical sector. With a team of experienced chemists, NuGenTec is dedicated to innovation and customer service, aiming to meet the specific needs of their clients with customized chemical solutions.

10. Norman, Fox & Co

• Website: norfoxchem.com
• Ownership type: Private
• Headquarters: Industry, California, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1971
• Headcount: 51-200
• LinkedIn: norman-fox-%26-co

Norman, Fox & Co is a chemical manufacturer and distributor based in Industry, California, with a history dating back to 1971. The company specializes in providing sustainable chemical solutions tailored to various sectors, including household cleaning, industrial applications, food and beverage, and personal care. With a workforce of approximately 44 employees, Norman Fox emphasizes quality and innovation in its offerings, aiming to enhance both everyday living and industrial excellence. Their product range reflects a commitment to health and sustainability, focusing on all-natural, non-GMO, and organic solutions. The company operates multiple locations across the United States, ensuring a broad reach and the ability to serve a diverse clientele. Their approach to business is characterized by a strong emphasis on customer service and transparency, which has fostered long-term partnerships and consistent profitability.

11. Miles Chemical Company Inc.

• Website: mileschemical.com
• Ownership type: Private
• Headquarters: Los Angeles, California, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1996
• Headcount: 51-200
• LinkedIn: miles-chemical-inc-

Miles Chemical Company Inc., founded in 1996 and based in Los Angeles, California, operates as a chemical distributor. The company specializes in providing a wide array of chemical products and services, including chemical distribution, environmental services, blending, and logistics. They cater to multiple industries such as metal manufacturing, electronics, food and beverage, and personal care. With a workforce of approximately 38 employees, Miles Chemical emphasizes efficient supply chain solutions and strict compliance with safety regulations. Their facilities in Arleta and Anaheim, California, support their operations, which include hazardous and non-hazardous waste transportation, custom packaging, and onsite technical support. The company is committed to quality, as evidenced by their ISO 9001:2015 certification and membership in the National Association of Chemical Distributors (NACD).

12. Goodwin Company

• Website: goodwininc.com
• Ownership type: Family Owned
• Headquarters: Garden Grove, California, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1922
• Headcount: 201-500
• LinkedIn: goodwininc1922

Goodwin Company, established in 1922, is a family-owned chemical contract manufacturer based in Garden Grove, California, with an additional facility in Lawrenceville, Georgia. The company specializes in blending, filling, and packaging services tailored for various industries, including household products, industrial chemicals, and agricultural applications. With a strong emphasis on quality and compliance, Goodwin is ISO 9001:2015 and ISO 14001:2015 certified, and has been EPA registered for over 30 years. Their extensive capabilities include strategic procurement, bulk chemical handling, and a full-service lab for product formulation and research. Goodwin has transitioned from manufacturing its own branded products to focusing solely on contract manufacturing, which now accounts for a significant portion of their business. This shift reflects their adaptability and commitment to meeting the evolving needs of their clients in the chemical sector.

13. Dura Chemicals, Inc

• Website: durachem.com
• Ownership type: Private
• Headquarters: Emeryville, California, United States (USA)
• Employee distribution: Spain 56%, United States (USA) 44%
• Founded year: 1948
• Headcount: 11-50
• LinkedIn: dura-chemicals-inc

Dura Chemicals, Inc. is a chemical manufacturer based in Emeryville, California, with a history dating back to 1948. The company specializes in metal organics and additives, providing products that serve various applications, including paints, coatings, printing inks, and fuel additives. Dura Chemicals prides itself on delivering customized solutions that not only enhance product performance but also ensure compliance with environmental standards. With a workforce of approximately 55 employees, the company operates on a global scale, with a significant portion of its business in Spain and the United States. Dura Chemicals is committed to innovation and customer satisfaction, continuously developing new products to meet the evolving demands of the chemical industry.

14. CCI Chemical

• Website: ccichemical.com
• Ownership type: Private
• Headquarters: Vernon, California, United States (USA)
• Employee distribution: United States (USA) 92%, India 8%
• Founded year: 1957
• Headcount: 51-200
• LinkedIn: cci-chemical

CCI Chemical, officially known as C.C.I. Chemical Corporation, is a privately held industrial chemical supplier based in Vernon, California. Established in 1957, the company specializes in custom-blended chemical solutions tailored for applications in wastewater treatment, water treatment, and industrial cleaning. CCI Chemical serves a variety of sectors, including oil refining, power production, and food processing, showcasing its ability to meet the specific needs of different industries. The company prides itself on maintaining high-quality standards through its own manufacturing facilities, which allows for greater control over product formulation and delivery. With a portfolio that includes over 150 USDA-approved cleaning formulas and a comprehensive line of process chemicals, CCI Chemical has positioned itself as a reliable partner for businesses requiring specialized chemical solutions. Their technical expertise is underscored by a team of experienced representatives, averaging 15 years in the industry, who work closely with clients to develop customized solutions. CCI Chemical's commitment to quality and service is evident in their extensive product offerings and their proactive approach to customer support, including on-site training and analysis services.

15. entrotech

• Website: entrotech.com
• Ownership type: Private
• Headquarters: San Francisco, California, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1999
• Headcount: 11-50
• LinkedIn: entrotech

Entrotech, founded in 1999 and based in San Francisco, California, is an advanced materials manufacturer that specializes in innovative solutions across various industries. The company is dedicated to creating new molecules and advanced materials, providing comprehensive product design and development services. Their clientele includes businesses in critical sectors such as life sciences and aerospace, where they aim to enhance product performance through cutting-edge material solutions. Entrotech operates with a strong emphasis on intellectual freedom, encouraging collaboration and creativity among its team. This approach has led to significant advancements in areas like battlefield medical care and intelligent paint technology for aerospace applications. With a workforce of around 30 employees, Entrotech is strategically positioned in key technology hubs, including locations in Columbus, Ohio, and Singapore, further solidifying its role in the global chemical manufacturing industry.

16. Calsak Corporation

• Website: calsak.com
• Ownership type: Corporate
• Headquarters: Gardena, California, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: September 2001
• Founded year: 1972
• Headcount: 11-50
• LinkedIn: calsak-corporation

Calsak Corporation, founded in 1972 and headquartered in Gardena, California, is a chemical distributor that specializes in polymers, colorants, and specialty chemicals. The company serves a variety of businesses in manufacturing and related sectors, providing high-quality products designed to enhance operational success. Calsak operates a network of distribution centers across the United States and Mexico, ensuring efficient service and timely delivery to its customers. Their product range includes custom synthesized specialty chemicals, commodity chemicals, engineering polymers, and various additives. Calsak's commitment to quality is underscored by their ISO 9001:2015 certification, which reflects their focus on customer satisfaction and operational excellence. With a strong foundation built on years of industry experience and strategic partnerships, Calsak Corporation continues to be a trusted source for chemical solutions.

17. M Chemical Company, Inc.

• Website: mchemical.com
• Ownership type: Corporate
• Headquarters: Los Angeles, California, United States (USA)
• Employee distribution: United States (USA) 50%, Mexico 27%, United Arab Emirates 14%, Other 9%
• Latest funding: January 2023
• Founded year: 1966
• Headcount: 11-50
• LinkedIn: m-chemical-company-inc-

M Chemical Company, Inc., based in Los Angeles, California, has been a player in the chemical manufacturing industry since its inception in 1966. The company specializes in producing specialty chemicals tailored for energy markets and polymers. Their product line includes activated alumina, catalysts, and various purification technologies, which are essential for large industrial customers in the refining and petrochemical sectors. M Chemical emphasizes rigorous quality control and customer service, ensuring that their products meet high standards. With a workforce of 43 employees and a global distribution network that spans the United States, Mexico, the United Arab Emirates, the Netherlands, and Canada, M Chemical is well-positioned to serve its clients effectively. The company has not reported any recent funding, indicating a stable operational model focused on its core competencies.

18. Signal Fluid Solutions

• Website: signalfluidsolutions.com
• Ownership type: Private
• Headquarters: Riverside, California, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2007
• Headcount: 11-50
• LinkedIn: signal-fluid-solutions

Signal Fluid Solutions, based in Riverside, California, is a private chemical manufacturer established in 2007. The company specializes in petroleum hydrocarbons and specialty chemicals, providing a range of products such as base oils, process oils, and aerosols. Their offerings cater to various industries, including food processing, agriculture, and industrial manufacturing. Signal Fluid Solutions operates through strategic partnerships, ensuring high-quality supply and logistics services for their customers. They also provide contract blending and logistics services, demonstrating their flexibility and responsiveness to client needs. With a dedicated team of 15 employees, the company emphasizes customer service and innovative solutions to enhance their clients' operations. Their focus on quality and reliability has earned them a reputation as a dependable supplier in the chemical manufacturing sector.

19. Southwall Technologies

• Website: southwall.com
• Ownership type: Corporate
• Headquarters: Palo Alto, California, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: November 2011
• Founded year: 1979
• Headcount: 51-200
• LinkedIn: southwall-technologies

Southwall Technologies, based in Palo Alto, California, is a company that has been active since 1979. It focuses on the development and production of advanced materials, particularly in the area of energy-efficient window films and coatings. These products are designed to enhance energy conservation in buildings, contributing to sustainability efforts in the construction and architecture sectors. Southwall's technology is utilized in various applications, including automotive and architectural glass, where energy efficiency is a growing concern. The company has not reported any recent funding, indicating a stable operational model without reliance on external financial support. Southwall Technologies continues to innovate within its niche, addressing the increasing demand for energy-efficient solutions in the chemical manufacturing industry.

20. eXoZymes (Nasdaq: EXOZ)

• Website: invizyne.com
• Ownership type: Private
• Headquarters: Monrovia, California, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2014
• Headcount: 11-50
• LinkedIn: exozymes

eXoZymes, known as Invizyne, is a biomanufacturing company based in Monrovia, California, founded in 2014. The company employs a team of 34 professionals dedicated to advancing enzyme-based systems for the production of valuable chemicals. Invizyne focuses on sustainable production methods, utilizing their proprietary cell-free technology platform to create natural ingredients, pharmaceuticals, and specialty chemicals. Their innovative approach allows for the efficient and environmentally friendly production of various compounds, including cannabinoids, biofuels, and nutraceuticals. Invizyne's technology has been validated through multiple publications in peer-reviewed journals, showcasing their commitment to scientific rigor and innovation in the chemical manufacturing industry.

Chemical Manufacturing Insights: Key Companies in California

Company	Headquarter	Size	Founded	Ownership
Enviro Tech, an Arxada Company	Modesto, California, United States (USA)	201-500	1991	Corporate
Geno	San Diego, California, United States (USA)	51-200	2000	Venture Capital
American Elements	Los Angeles, California, United States (USA)	201-500	1998	Private
Eastar Chemical Corporation	Sacramento, California, United States (USA)	201-500	1986	Private
Argo Chemical	Bakersfield, California, United States (USA)	11-50	1980	Private
Lygos	Hayward, California, United States (USA)	51-200	2011	Venture Capital
Zymergen, Inc.	Emeryville, California, United States (USA)	501-1000	2013	Corporate
Novvi, LLC	Alameda, California, United States (USA)	51-200	2003	Private
NuGenTec	Emeryville, California, United States (USA)	11-50	1997	Private
Norman, Fox & Co	Industry, California, United States (USA)	51-200	1971	Private
Miles Chemical Company Inc.	Los Angeles, California, United States (USA)	51-200	1996	Private
Goodwin Company	Garden Grove, California, United States (USA)	201-500	1922	Family Owned
Dura Chemicals, Inc	Emeryville, California, United States (USA)	11-50	1948	Private
CCI Chemical	Vernon, California, United States (USA)	51-200	1957	Private
entrotech	San Francisco, California, United States (USA)	11-50	1999	Private
Calsak Corporation	Gardena, California, United States (USA)	11-50	1972	Corporate
M Chemical Company, Inc.	Los Angeles, California, United States (USA)	11-50	1966	Corporate
Signal Fluid Solutions	Riverside, California, United States (USA)	11-50	2007	Private
Southwall Technologies	Palo Alto, California, United States (USA)	51-200	1979	Corporate
eXoZymes (Nasdaq: EXOZ)	Monrovia, California, United States (USA)	11-50	2014	Private

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