North Carolina is home to a vibrant pharmaceutical manufacturing sector, focusing on the development and production of innovative drugs and therapies. This industry includes pharmaceutical firms, biotech companies, and contract manufacturers. They produce a range of products, from over-the-counter medications to complex biologics and generics. The state's rich talent pool and research institutions are driving advancements in drug delivery and biopharmaceuticals. With increasing focus on biotechnologies and personalized medicine, companies are adapting to the rising demand for innovative, efficient solutions that can quickly meet emerging healthcare needs. Employment opportunities in this field are also growing, highlighting its importance.

The companies featured in this list vary in size and specialization, reflecting North Carolina's dynamic industry. Ranging from small biotech firms to larger corporate players, they were founded between 1975 and 2022. Headquarters are primarily located in scientific hubs such as Durham and Morrisville. Specialties include contract development, biologics manufacturing, and cutting-edge therapeutic solutions. Moreover, many of these companies have received substantial funding to support their development, illustrating both investor confidence and the promising future of pharmaceutical manufacturing in the region.

Read on to explore the top pharmaceutical manufacturing companies in North Carolina.

Top 19 Pharmaceutical Manufacturing Companies in North Carolina

1. FUJIFILM Diosynth Biotechnologies

• Website: fujifilmdiosynth.com
• Ownership type: Corporate
• Headquarters: Morrisville, North Carolina, United States (USA)
• Employee distribution: Denmark 43%, United States (USA) 40%, United Kingdom (UK) 17%
• Latest funding: $890.0M, August 2019
• Founded year: 2011
• Headcount: 1001-5000
• LinkedIn: fujifilm-diosynth-biotechnologies

FUJIFILM Diosynth Biotechnologies is a biotechnology company based in Morrisville, North Carolina, specializing in contract development and manufacturing services for biologics, vaccines, and advanced therapies. Founded in 2011, the company has quickly established itself as a key player in the pharmaceutical manufacturing sector. They partner with pharmaceutical and biotechnology firms, providing expertise in cGMP processes to ensure the safe and effective delivery of products. With a global footprint that includes facilities in the United States, Denmark, the United Kingdom, and Japan, FUJIFILM Diosynth Biotechnologies supports clients through all phases of drug development, from pre-clinical studies to commercialization. Their commitment to quality is evident in their proactive approach to continuous improvement and their investment in state-of-the-art manufacturing capabilities. The company has also received substantial funding, with a reported amount of $890 million in 2019, which highlights their ambition to expand and enhance their service offerings in the biopharmaceutical industry.

2. Bamboo Therapeutics, Inc. a wholly owned subsidiary of Pfizer Inc.

• Website: bambootherapeutics.com
• Ownership type: Corporate
• Headquarters: Chapel Hill, North Carolina, United States (USA)
• Latest funding: $654.0M, August 2016
• Founded year: 2014
• Headcount: 11-50
• LinkedIn: bamboo-therapeutics

Bamboo Therapeutics, Inc., a wholly owned subsidiary of Pfizer Inc., is based in Chapel Hill, North Carolina. Founded in 2014, the company is dedicated to the development and manufacturing of innovative therapies, particularly focusing on gene therapy for rare diseases. This specialization allows Bamboo Therapeutics to address unmet medical needs through advanced research and development. As part of Pfizer, Bamboo Therapeutics benefits from the larger company's extensive resources and expertise in the pharmaceutical sector. The company has received substantial funding, amounting to $654 million, which underscores its potential and the confidence investors have in its mission to create impactful treatments. Bamboo Therapeutics is actively involved in the pharmaceutical industry, contributing to the advancement of therapies that can significantly improve patient outcomes.

3. BE Pharmaceuticals, Inc.

• Website: be-pharmaceuticals.com
• Ownership type: Private
• Headquarters: Cary, North Carolina, United States (USA)
• Employee distribution: India 90%, United States (USA) 10%
• Founded year: 2019
• Headcount: 1-10
• LinkedIn: be-pharmaceuticals-inc

BE Pharmaceuticals, Inc., based in Cary, North Carolina, is a pharmaceutical manufacturer that specializes in injectable products and vaccines. Established in 2019, the company operates from a USFDA approved facility and is part of Biological E. Limited, a prominent player in vaccine partnerships. BE Pharmaceuticals supplies its products to a variety of healthcare facilities, including hospitals and pharmacies, ensuring access to essential medications. The company has launched several products and has a robust pipeline with over 20 products in various stages of development. Their commitment to quality and reliability is evident in their operations, which are designed to meet the stringent requirements of the pharmaceutical industry. With a focus on expanding their product offerings, BE Pharmaceuticals aims to introduce 5-7 new products annually, further solidifying their role in the pharmaceutical manufacturing sector.

4. Bright Path Laboratories

• Website: brightpathlabs.com
• Ownership type: Private
• Headquarters: Kannapolis, North Carolina, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: Other (Debt), $8.5M, November 2021
• Founded year: 2019
• Headcount: 11-50
• LinkedIn: brightpathlabs

Bright Path Laboratories, established in 2019 and based in Kannapolis, North Carolina, is a pharmaceutical manufacturer dedicated to transforming the way medicines are sourced and produced in the United States. The company specializes in developing and manufacturing active pharmaceutical ingredients (APIs) and drug formulations, with a strong emphasis on sustainability and affordability. Utilizing advanced manufacturing technologies, including their patented Spinning-Tube-in-Tube (STT) Reactor™, Bright Path aims to produce high-quality medicines more efficiently and with less environmental impact. Their commitment to addressing the healthcare crisis in America is evident in their focus on securing a reliable supply chain for essential medicines, particularly in light of recent disruptions. Bright Path has also received $8.46 million in funding, reflecting confidence in their innovative approach and potential for growth in the pharmaceutical sector.

5. MedPharm

• Website: medpharm.com
• Ownership type: Corporate
• Headquarters: Durham, North Carolina, United States (USA)
• Employee distribution: United Kingdom (UK) 49%, United States (USA) 48%, Other 3%
• Latest funding: July 2024
• Founded year: 1994
• Headcount: 51-200
• LinkedIn: medpharm

MedPharm, founded in 1994 and based in Durham, North Carolina, operates as a contract development and manufacturing organization (CDMO) focused on the pharmaceutical industry. The company provides a comprehensive suite of services, including formulation development, in vitro testing, and commercial production of topical and transdermal drug products. MedPharm's clientele primarily consists of pharmaceutical companies seeking specialized knowledge in drug formulation and regulatory compliance. Recently, MedPharm merged with Tergus Pharma, creating a stronger entity with enhanced capabilities in topical drug development. With a workforce of approximately 264 employees, MedPharm boasts a significant presence in both the United States and the United Kingdom, reflecting its global operational reach. The company has successfully supported the development of over 55 market-approved products, showcasing its expertise and reliability in navigating the complexities of pharmaceutical manufacturing.

6. Mycovia Pharmaceuticals

• Website: mycovia.com
• Ownership type: Private
• Headquarters: Durham, North Carolina, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2018
• Headcount: 11-50
• LinkedIn: mycovia-pharmaceuticals

Mycovia Pharmaceuticals, based in Durham, North Carolina, is a biopharmaceutical company founded in 2018. The company is dedicated to developing innovative therapies aimed at addressing overlooked medical conditions, with a strong emphasis on women's health. Mycovia's mission is to provide treatment equality and support for patients who face unmet medical needs. Their flagship product, VIVJOA® (oteseconazole), is designed to treat conditions that have not been adequately addressed in the past. Mycovia is committed to advancing research and commercialization of novel pharmaceuticals, focusing on empowering patients and healthcare providers alike. The company operates with a clear set of values, including respect, integrity, and innovation, which guide their efforts in making a meaningful impact in the healthcare community.

7. Metrics Contract Services

• Website: metricscontractservices.com
• Ownership type: Corporate
• Headquarters: Greenville, North Carolina, United States (USA)
• Latest funding: $475.0M, August 2022
• Founded year: 1994
• Headcount: 501-1000
• LinkedIn: metrics-inc-

Metrics Contract Services, based in Greenville, North Carolina, is a contract development and manufacturing organization (CDMO) that specializes in pharmaceutical and biotechnology services. Founded in 1994, the company has built a reputation for offering a comprehensive range of solutions that include drug development, manufacturing, and clinical supply services. Metrics Contract Services plays a vital role in helping pharmaceutical and biotech companies navigate the complexities of bringing their products to market. Their expertise spans various stages of drug development, from preclinical phases to commercial manufacturing. The company has also received significant funding, with a reported amount of $475 million in August 2022, indicating strong investor confidence in their operations and growth potential.

8. Qualicaps

• Website: qualicaps.com
• Ownership type: Corporate
• Headquarters: Whitsett, North Carolina, United States (USA)
• Employee distribution: Spain 34%, Romania 32%, United States (USA) 22%, Other 12%
• Latest funding: March 2013
• Founded year: 1992
• Headcount: 1001-5000
• LinkedIn: qualicaps

Qualicaps, founded in 1992 and based in Whitsett, North Carolina, is a pharmaceutical manufacturer that specializes in the production of high-quality capsules and pharmaceutical processing equipment. The company serves a variety of clients, including pharmaceutical manufacturers and health-related businesses, providing essential products that adhere to stringent industry standards. With a workforce distributed across several countries, including Spain, Romania, and Brazil, Qualicaps has established a global footprint. Their commitment to innovation is evident in their development of advanced capsule technologies and equipment designed to enhance drug delivery systems. Qualicaps is recognized for its expertise in producing both gelatin and plant-based capsules, catering to the evolving needs of the pharmaceutical market. They also offer a range of services, including technical support and equipment customization, further solidifying their role as a partner in the pharmaceutical manufacturing process.

9. Novex Innovations

• Website: novexinnovations.com
• Ownership type: Corporate
• Headquarters: Winston-Salem, North Carolina, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: $50.0M, June 1999
• Founded year: 2014
• Headcount: 11-50
• LinkedIn: novexinnovations

Novex Innovations, founded in 2014 and based in Winston-Salem, North Carolina, operates as a contract development and manufacturing organization (CDMO) dedicated to the healthcare sector. The company offers a comprehensive suite of services that includes product and process development, cGMP manufacturing, and regulatory support tailored for pharmaceutical and biotech companies. With a focus on accelerating the development and commercialization of innovative healthcare solutions, Novex partners with clients to navigate the complexities of bringing products to market. Their facilities are equipped to handle a range of manufacturing needs, from small batch requirements to larger scale production, ensuring compliance with stringent regulatory standards. Novex's expertise extends across various divisions, including biologics, drugs, and medical devices, making them a versatile partner in the pharmaceutical manufacturing industry.

10. Accord Healthcare US

• Website: accordhealthcare.us
• Ownership type: Private
• Headquarters: Durham, North Carolina, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2002
• Headcount: 201-500
• LinkedIn: accord-healthcare-us

Accord Healthcare US, a subsidiary of Intas Pharmaceuticals, is a pharmaceutical company based in Durham, North Carolina. Founded in 2002, the company specializes in the development and distribution of generic medications. Accord Healthcare is dedicated to providing high-quality, affordable pharmaceutical products to healthcare providers and patients. Their product offerings include a range of dosage forms, such as oral tablets and injectables, with a notable presence in oncology, where they hold a significant market share in chemotherapy injectables. The company operates with a strong emphasis on research and development, employing a skilled team of scientists and healthcare professionals to navigate regulatory pathways and foster innovation. With three FDA-approved manufacturing facilities in India, Accord Healthcare maintains a solid regulatory track record, having successfully completed numerous inspections. Their mission is to empower physicians and patients by ensuring access to essential medications, thereby improving health outcomes across the board.

11. Inhalon Biopharma

• Website: inhalon.com
• Ownership type: Venture Capital
• Headquarters: Durham, North Carolina, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: Other (Grant), $2.0M, November 2022
• Founded year: 2018
• Headcount: 1-10
• LinkedIn: inhalon-biopharma

Inhalon Biopharma is a biotechnology company based in Durham, North Carolina, founded in 2018. The company specializes in developing inhaled antibody treatments aimed at combating acute respiratory infections. Their product pipeline includes treatments for respiratory syncytial virus (RSV), influenza, human metapneumovirus, and SARS-CoV-2. Inhalon is notable for its unique 'test-to-treat' model, which allows for self-administration of treatments at home, enhancing patient convenience and potentially improving health outcomes. The company has received significant funding, including a $7 million grant from the U.S. Army Medical Research and Development Command to study inhaled therapies for COVID-19, and a $2 million grant from the National Institutes of Health for the development of a treatment for RSV. This funding supports their ongoing research and development efforts, positioning Inhalon as a relevant player in the pharmaceutical manufacturing sector.

12. Exela Pharma Sciences LLC

• Website: exelapharma.com
• Ownership type: Private
• Headquarters: Lenoir, North Carolina, United States (USA)
• Employee distribution: United States (USA) 98%, India 2%
• Latest funding: September 2021
• Founded year: 2005
• Headcount: 501-1000
• LinkedIn: exela-pharma-sciences-llc

Exela Pharma Sciences LLC, founded in 2005 and based in Lenoir, North Carolina, is a private pharmaceutical manufacturer that specializes in sterile injectable products. The company operates two main business units: Finished Drug Products and Contract Development and Manufacturing Organization (CDMO). Exela offers comprehensive services that include research and development, quality assurance, and logistics support, primarily targeting healthcare providers and pharmaceutical companies. Their facilities are FDA inspected and capable of producing over one hundred million sterilized units annually, showcasing their significant manufacturing capacity. Exela is particularly focused on addressing drug shortages, especially in neonatal and pediatric care, which highlights their commitment to improving patient outcomes. The company has built a reputation for reliability and quality, with a workforce that emphasizes excellence in service and product delivery.

13. KBI Biopharma

• Website: kbibiopharma.com
• Ownership type: Venture Capital
• Headquarters: Durham, North Carolina, United States (USA)
• Employee distribution: United States (USA) 88%, Switzerland 12%
• Latest funding: December 2016
• Founded year: 1996
• Headcount: 1001-5000
• LinkedIn: kbi-biopharma

KBI Biopharma, founded in 1996 and based in Durham, North Carolina, is a biopharmaceutical development and manufacturing company. With a workforce of over 1,600 employees, KBI specializes in providing comprehensive services that include cell line development, process development, analytical development, formulation development, and both clinical and commercial manufacturing. The company serves a variety of clients in the pharmaceutical and biotechnology sectors, assisting them in navigating the complexities of drug development. KBI Biopharma operates multiple facilities across the United States and Europe, ensuring a robust presence in the industry. Their proprietary technologies, such as the SUREtechnology Platform™ and PUREplatform™, enhance their capabilities in producing biologics efficiently and effectively. KBI's commitment to high standards and regulatory compliance underscores their role in advancing biopharmaceutical solutions.

14. Immorna

• Website: immorna.com
• Ownership type: Private Equity
• Headquarters: Morrisville, North Carolina, United States (USA)
• Employee distribution: United States (USA) 83%, China 17%
• Latest funding: Other (Grant), August 2024
• Founded year: 2019
• Headcount: 51-200
• LinkedIn: immorna

Immorna is a biotechnology firm based in Morrisville, North Carolina, founded in 2019. The company focuses on RNA-based therapeutics and vaccines, providing contract development and manufacturing services tailored to the needs of pharmaceutical and research organizations. Immorna has established a robust platform for RNA synthesis, purification, and analytical testing, which is essential for both clinical and commercial development. The company has developed proprietary RNA delivery vehicles, including polymers and lipid nanoparticles, to enhance the efficacy of its therapeutics. Immorna's pipeline includes candidates for cancer immunotherapy, infectious diseases, and rare genetic disorders, showcasing its commitment to addressing significant medical needs. The company has also received FDA IND clearance for its drug candidates, further solidifying its position in the industry. Immorna operates with a global footprint, with facilities in the United States and China, and has a growing intellectual property portfolio that supports its innovative approaches in RNA technology.

15. Alcami Corporation

• Website: alcami.com
• Ownership type: Private
• Headquarters: Wilmington, North Carolina, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1979
• Headcount: 501-1000
• LinkedIn: alcami-corporation

Alcami Corporation, based in Wilmington, North Carolina, is a pharmaceutical services company that has been active since 1979. The firm specializes in drug product manufacturing, laboratory services, and GMP storage solutions, catering primarily to pharmaceutical and biotechnology companies. Alcami supports clients throughout the drug development lifecycle, from preclinical stages to commercial launch, ensuring that their operations meet stringent regulatory standards. The company offers a range of services, including sterile fill-finish manufacturing, oral solid dose production, and comprehensive analytical testing. With a workforce of approximately 1,147 employees, Alcami is positioned to provide essential support to its clients, helping them navigate the complexities of drug development and manufacturing. Their facilities are equipped to handle various pharmaceutical needs, including the management of controlled substances, which adds to their operational capabilities.

16. AreteiaTx

• Website: areteiatx.com
• Ownership type: Venture Capital
• Headquarters: Durham, North Carolina, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: Series A, $75.0M, February 2024
• Founded year: 2022
• Headcount: 11-50
• LinkedIn: areteiatx

Areteia Therapeutics, based in Durham, North Carolina, is a biotechnology company founded in 2022. The firm is dedicated to developing dexpramipexole, an innovative oral treatment aimed at eosinophilic asthma, a severe form of asthma that affects a significant number of patients worldwide. AreteiaTx is currently conducting global Phase III clinical trials to validate the safety and efficacy of dexpramipexole, which has shown promise in previous studies involving over 1,500 patients. The company has recently secured $75 million in Series A funding, which underscores investor confidence in their approach and potential. With a team of experienced drug developers, AreteiaTx is focused on transforming the treatment landscape for patients suffering from eosinophilic asthma, providing a much-needed alternative to existing therapies.

17. CMP Pharma, Inc.

• Website: cmppharma.com
• Ownership type: Private Equity
• Headquarters: Farmville, North Carolina, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: August 2012
• Founded year: 1975
• Headcount: 11-50
• LinkedIn: cmp-pharma-inc.

CMP Pharma, Inc., founded in 1975 and based in Farmville, North Carolina, is a private equity-owned pharmaceutical company that specializes in the development and manufacturing of oral liquid and semi-solid topical products. The company is dedicated to addressing critical needs in niche markets, particularly for patients who have difficulty swallowing traditional medications. CMP Pharma's product portfolio includes FDA-approved medications that provide safe and effective alternatives for healthcare professionals and facilities. Their notable achievements include being the first to receive FDA approval for oral liquid suspensions of atorvastatin, tadalafil, and amlodipine, among others. This focus on innovative formulations positions CMP Pharma as a key player in the pharmaceutical industry, particularly in the acute and long-term care settings. The company operates with a commitment to quality and compliance, ensuring that their products meet stringent regulatory standards.

18. Kowa Research Institute, Inc.

• Website: kowaus.com
• Ownership type: Corporate
• Headquarters: Morrisville, North Carolina, United States (USA)
• Employee distribution: United States (USA) 96%, Vietnam 4%
• Latest funding: August 2008
• Founded year: 1997
• Headcount: 11-50
• LinkedIn: kowa-research-institute-inc.

Kowa Research Institute, Inc., based in Morrisville, North Carolina, is a pharmaceutical company that specializes in the clinical development of new drugs. Established in 1997, it operates as a division of Kowa Co., Ltd., a major privately held company in Japan. Kowa Research Institute is dedicated to addressing lifestyle-related diseases, immunity, and inflammation through innovative drug development. The company collaborates with various healthcare organizations and research institutions to advance its clinical trials and research initiatives. With a workforce of around 54 employees, Kowa Research Institute has expanded its operations to include a strategic headquarters in Boston, Massachusetts, which oversees global clinical development activities. Their research efforts are supported by laboratories in Japan, focusing on a range of therapeutic areas, including cardiovascular and metabolic diseases. Kowa Research Institute's commitment to advancing drug candidates through clinical trials underscores its active role in the pharmaceutical sector.

19. Ironshore Pharmaceuticals Inc.

• Website: ironshorepharma.com
• Ownership type: Corporate
• Headquarters: Durham, North Carolina, United States (USA)
• Latest funding: $525.0M, July 2024
• Founded year: 2008
• Headcount: 201-500
• LinkedIn: ironshore-pharmaceuticals-inc

Ironshore Pharmaceuticals Inc., based in Durham, North Carolina, is a pharmaceutical company established in 2008. The firm is dedicated to developing innovative treatment options, particularly for Attention Deficit Hyperactivity Disorder (ADHD). They utilize proprietary drug delivery systems designed to enhance the effectiveness of medications for patients and caregivers. Ironshore engages in extensive research and development efforts to tackle unmet medical needs within the pharmaceutical sector. Recently, the company secured $525 million in funding, reflecting strong investor interest and support for their initiatives. Their flagship product, JORNAY PM, is a first-in-class treatment for ADHD, showcasing their commitment to improving patient outcomes through advanced therapeutic solutions.

Pharmaceutical Manufacturing Insights: Key Companies in North Carolina

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