Michigan is a hub for pharmaceutical manufacturing, featuring various companies dedicated to innovative health solutions. This industry is characterized by firms engaged in the development, production, and distribution of medications ranging from generic drugs to specialty pharmaceuticals. Companies leverage advanced technologies and rigorous quality standards to enhance patient care. Insights show a growing emphasis on sustainable practices and personalized medicine, indicating a forward-thinking trajectory in the sector. As healthcare needs evolve, Michigan's pharmaceutical manufacturing is poised for expansion, with firms increasingly aligning research with emerging trends in health and wellness, contributing to the state’s economic growth.

This list highlights 19 noteworthy pharmaceutical manufacturing companies in Michigan. Ranging from well-established entities like Guna Spa, founded in 1983, to newer entrants such as Neopharmed Gentili S.P.A., created in 2018, these companies vary in size and specialization. Most are headquartered in cities like Milan and Grand Rapids, with a focus on innovative healthcare solutions, including generics, homeopathic products, and advanced drug delivery technologies. The companies operate with diverse workforce sizes, showcasing a mix of innovation, experience, and shared commitment to advancing health solutions for patients.

Continue reading to discover the top pharmaceutical manufacturing companies in Michigan.

Top 19 Pharmaceutical Manufacturing Companies in Michigan

1. Indena

• Website: indena.com
• Ownership type: Corporate
• Headquarters: Milan, Michigan, United States (USA)
• Employee distribution: Italy 76%, France 17%, India 5%, Other 2%
• Latest funding: November 2019
• Founded year: 1921
• Headcount: 501-1000
• LinkedIn: indena

Indena, established in 1921 and headquartered in Milan, is a pharmaceutical and nutraceutical manufacturer that specializes in botanical derivatives. The company is dedicated to engineering nature to support human health, providing high-quality health solutions to pharmaceutical and nutraceutical businesses. Indena's product offerings include a wide range of botanical extracts and innovative technologies, such as Indena Phytosome™ Technology, which enhances the bioavailability of active ingredients. With a workforce of around 494 employees, the company operates globally, managing a sustainable supply chain and ensuring quality through rigorous research and development. Indena's commitment to sustainability is evident in their practices, which prioritize environmental responsibility and the ethical sourcing of raw materials. They have established a strong presence in the pharmaceutical sector, serving clients in over 80 countries and maintaining production facilities that adhere to high standards of quality and safety.

2. Neopharmed Gentili S.P.A.

• Website: neogen.it
• Ownership type: Private
• Headquarters: Milan, Michigan, United States (USA)
• Employee distribution: Italy 100%
• Founded year: 2018
• Headcount: 201-500
• LinkedIn: neopharmed-gentili-s.p.a.

Neopharmed Gentili S.P.A. is an Italian pharmaceutical company based in Milan, founded in 2018. The company is dedicated to the commercialization of high therapeutic value solutions, focusing on various therapeutic areas such as cardio-metabolic, neuro-psychiatric, vascular, osteo-articular, pneumological, gastroenterological, and antibiotic treatments. Neopharmed Gentili provides a range of products including pharmaceuticals, medical devices, dietary supplements, and cosmetics, aiming to enhance health outcomes and improve the quality of life for patients. The company has built strategic partnerships with notable multinational corporations, such as MSD and Teva, to expand its market presence and product offerings. With a workforce of approximately 426 employees, Neopharmed Gentili is committed to innovation and research, striving to develop effective treatments for chronic conditions affecting millions of patients annually.

3. Stewart Italia srl

• Website: stewartitalia.it
• Ownership type: Private
• Headquarters: Milan, Michigan, United States (USA)
• Employee distribution: Italy 100%
• Founded year: 2005
• Headcount: 51-200
• LinkedIn: stewart-italia-srl

Stewart Italia srl, founded in 2005 and based in Milan, Michigan, is a private pharmaceutical company dedicated to the research, development, and commercialization of innovative health products. The company specializes in pharmaceuticals, medical devices, and cosmetics, with a strong emphasis on therapeutic areas such as pediatrics and gynecology. Stewart Italia operates under strict quality standards, ensuring that their products are manufactured in compliance with Good Manufacturing Practices (GMP). They have successfully registered multiple products and patents, showcasing their commitment to scientific excellence. The company collaborates with hospitals, universities, and scientific institutions to enhance their research and development efforts. Their pharmacovigilance practices further underline their dedication to patient safety and product efficacy. Stewart Italia's product range includes solutions for respiratory health, oral care, women's health, dermatological needs, and immune support, reflecting their focus on addressing specific health concerns.

4. Towa Pharma Italia

• Website: pensapharma.it
• Ownership type: Private
• Headquarters: Milan, Michigan, United States (USA)
• Founded year: 2007
• Headcount: 11-50
• LinkedIn: towapharmaspain

Towa Pharma Italia, founded in 2007 and based in Milan, Michigan, is a private pharmaceutical company that focuses on the development and commercialization of generic drugs and health supplements. As a subsidiary of Towa Pharmaceutical Co., Ltd., a well-established entity in the pharmaceutical sector, Towa Pharma Italia aims to optimize healthcare spending while ensuring high-quality medication options for patients. The company serves healthcare professionals and pharmacies, emphasizing effective communication and support for its clients. Towa Pharma Italia is committed to sustainability and ethical practices in its manufacturing processes, aligning with modern industry standards. The company has a network of sales agents across Italy, ensuring a broad reach within the market. Their product offerings include a range of generic medications and health supplements under the Pensavital brand, which focuses on everyday wellness. Towa Pharma Italia's dedication to quality and patient care positions it as a relevant player in the pharmaceutical manufacturing industry.

5. Guna Spa

• Website: guna.com
• Ownership type: Private
• Headquarters: Milan, Michigan, United States (USA)
• Employee distribution: Italy 99%
• Founded year: 1983
• Headcount: 201-500
• LinkedIn: guna-s-p-a-

Guna Spa, established in 1983 and based in Milan, Italy, is a pharmaceutical company that specializes in the production and distribution of low-dose homeopathic medicines, medical devices, and food supplements. With a workforce of approximately 326 employees, Guna operates primarily in Italy, but its products are available in over 40 countries through exclusive distributors. The company emphasizes scientific research and social responsibility, investing in clinical studies to validate the efficacy and safety of its products. Guna is also involved in educational initiatives for healthcare professionals, promoting a better understanding of complementary medicine. Their manufacturing facility in Milan is noted for its advanced technology and adherence to high-quality standards, including ISO certifications. Guna's commitment to ethical practices and innovative health solutions makes it a notable player in the pharmaceutical industry.

6. Doc Generici

• Website: docgenerici.it
• Ownership type: Private Equity
• Headquarters: Milan, Michigan, United States (USA)
• Employee distribution: Italy 100%
• Latest funding: June 2022
• Founded year: 1996
• Headcount: 51-200
• LinkedIn: doc-generici-srl

Doc Generici S.r.l. is a pharmaceutical company based in Milan, Italy, founded in 1996. The company specializes in the production and distribution of generic medicines, with a notable emphasis on ophthalmic products. By focusing on generic alternatives, Doc Generici aims to provide healthcare professionals and patients with affordable and effective treatment options for a variety of health conditions. The company has developed a comprehensive portfolio of products, particularly in the field of ophthalmology, which includes treatments for conditions such as glaucoma and dry eye. Their commitment to quality and innovation is evident in their operations, which adhere to high standards of pharmaceutical manufacturing. With a workforce of approximately 269 employees, Doc Generici is a mid-sized player in the pharmaceutical sector, dedicated to enhancing patient care through accessible medication.

7. Corium Innovations

• Website: coriuminv.com
• Ownership type: Private Equity
• Headquarters: Grand Rapids, Michigan, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: $100.0M, October 2022
• Founded year: 1999
• Headcount: 51-200
• LinkedIn: coriuminnovations

Corium Innovations, based in Grand Rapids, Michigan, is a pharmaceutical company founded in 1999. The firm specializes in advanced drug delivery technologies, focusing on transdermal and oral thin film products. These innovations aim to enhance patient adherence to medication, addressing challenges such as gastrointestinal issues, forgetfulness, and needle aversion. Corium operates as a contract development and manufacturing organization (CDMO), providing a full range of development and manufacturing capabilities to pharmaceutical companies and healthcare providers. The company has a robust history of innovation, holding over 90 patents related to drug delivery technologies. In 2022, Corium secured $100 million in funding, reflecting strong market confidence in their capabilities and future prospects. Their commitment to creating effective healthcare solutions is evident in their partnerships and feasibility programs designed to test new drug delivery concepts.

8. The Tetra Corporation

• Website: thetetracorp.com
• Ownership type: Private
• Headquarters: Eaton Rapids, Michigan, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2003
• Headcount: 201-500
• LinkedIn: the-tetra-corporation

The Tetra Corporation, founded in 2003 and based in Eaton Rapids, Michigan, is a private healthcare company that specializes in antifungal treatments and advanced healthcare solutions. With a workforce of approximately 201-500 employees, the company focuses on developing clinically proven products that aim to enhance patient outcomes. Their product line includes notable offerings such as GlyCylic®, ALAPLEX™, and various formulations designed to treat fungal infections effectively. The Tetra Corporation operates an FDA registered laboratory, ensuring that their products meet stringent safety and efficacy standards. Their commitment to research and development is evident in their patented technologies, such as the soluble tolnaftate microemulsion used in Formula 7®. The company serves healthcare providers and patients, providing trusted solutions for conditions like athlete's foot and other fungal infections.

9. Dipharma Inc.

• Website: dipharmainc.com
• Ownership type: Private
• Headquarters: Kalamazoo, Michigan, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2012
• Headcount: 51-200
• LinkedIn: dipharma-inc

Dipharma Inc., based in Kalamazoo, Michigan, is a private pharmaceutical manufacturer that operates under the umbrella of Dipharma Francis S.r.l. Founded in 2012, the company specializes in Contract Development and Manufacturing Organization (CDMO) services, focusing on the synthesis of active pharmaceutical ingredients (APIs). Dipharma offers a wide range of high-quality APIs, catering to the needs of pharmaceutical companies and helping them navigate the complexities of drug development. The company prides itself on its technical expertise and ability to provide tailored solutions, ensuring that clients can rely on them for efficient and effective manufacturing processes. Dipharma's facilities are compliant with Good Manufacturing Practices (GMP), and they have successfully passed inspections from regulatory bodies such as the US FDA and the Italian Medicines Agency. This commitment to quality and safety positions Dipharma as a trusted partner in the pharmaceutical industry.

10. Caraco Pharmaceutical Laboratories

• Website: caraco.com
• Ownership type: Private
• Headquarters: Detroit, Michigan, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1984
• Headcount: 201-500
• LinkedIn: caraco-pharmaceutical-laboratories

Caraco Pharmaceutical Laboratories, based in Detroit, Michigan, is a private company that specializes in the production of generic and specialty medications. Founded in 1984, Caraco is a subsidiary of Sun Pharmaceutical Industries Ltd., which is recognized for its extensive portfolio of medications that cater to various therapeutic areas. The company focuses on providing affordable healthcare solutions and has established a strong presence in the U.S. market. Caraco's product range includes generics, branded generics, and active pharmaceutical ingredients, serving healthcare professionals and patients across the country. With a workforce of approximately 94 employees, Caraco is dedicated to maintaining high standards of quality and compliance in its manufacturing processes, contributing to the overall healthcare landscape.

11. Errekappa Euroterapici

• Website: errekappa.it
• Ownership type: Private
• Headquarters: Milan, Michigan, United States (USA)
• Employee distribution: Italy 100%
• Founded year: 1989
• Headcount: 51-200
• LinkedIn: errekappa-euroterapici-s.p.a.-in-forma-abbreviata-anche-sotto-forma-di-sigla-rk-s.p.a.

Errekappa Euroterapici S.p.A. is an Italian pharmaceutical company based in Milan, established in 1989. The company is dedicated to developing innovative therapeutic solutions, primarily in the fields of cardiology and clinical nutrition. With a workforce of approximately 73 employees, Errekappa focuses on providing healthcare professionals and patients with a range of products, including medications, nutritional supplements, and medical foods. Their approach is rooted in evidence-based practices, and they actively conduct clinical studies to support the efficacy of their offerings. Over the years, Errekappa has built a reputation for its commitment to improving health outcomes, particularly for patients with specific nutritional needs. The company emphasizes the importance of clinical nutrition and has been involved in various therapeutic areas, including immune defense, dyslipidemia, and cognitive functions. Their mission is to integrate pharmacological therapy with metabolic therapy, aiming for a holistic approach to patient care.

12. Bridge Organics Co

• Website: bridgeorganics.com
• Ownership type: Private
• Headquarters: Vicksburg, Michigan, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1997
• Headcount: 11-50
• LinkedIn: bridge-organics-co

Bridge Organics Co, founded in 1997 and based in Vicksburg, Michigan, operates as a contract research organization (CRO) with a focus on chemical manufacturing and process development. The company serves a variety of clients in the pharmaceutical, agricultural, and biotech industries, providing essential services such as contract research manufacturing and the multi-step synthesis of complex organic compounds. With a facility that includes fully equipped R&D labs and a pilot plant, Bridge Organics is well-equipped to handle projects ranging from small-scale synthesis to larger manufacturing campaigns. Their team of experienced chemists brings expertise in areas such as steroid, heterocyclic, prostaglandin, and peptide research, which is critical for pharmaceutical applications. The company prides itself on its ability to be flexible and responsive to customer needs, ensuring that they can adapt to the specific requirements of each project. Bridge Organics has established a solid reputation for delivering competitive pricing and thorough analytical characterization of products, making them a trusted partner for many in the pharmaceutical sector.

13. TSRL, Inc

• Website: tsrlinc.com
• Ownership type: Private
• Headquarters: Ann Arbor, Michigan, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1986
• Headcount: 11-50
• LinkedIn: tsrl-inc

TSRL, Inc., based in Ann Arbor, Michigan, is a biotechnology firm established in 1986. The company specializes in the development of therapeutics aimed at combating infectious diseases. With a dedicated facility that includes 5,000 square feet of wet lab space, TSRL provides essential infrastructure for preclinical research. They are particularly known for their innovative microneedle patch technology, which aims to improve drug delivery methods for conditions like influenza and other viral infections. TSRL collaborates with various academic institutions and industry partners to advance their drug development projects. Their expertise in pharmaceutical sciences, combined with a strong track record of securing non-dilutive funding, supports their mission to tackle severe infections, including multi-drug resistant strains. Recent projects include the development of a first-in-class oral antibiotic and a microneedle patch for influenza treatment, showcasing their commitment to addressing unmet medical needs.

14. BlueWillow Biologics, Inc.

• Website: bluewillow.com
• Ownership type: Venture Capital
• Headquarters: Ann Arbor, Michigan, United States (USA)
• Latest funding: Other (Grant), September 2018
• Founded year: 2000
• Headcount: 11-50
• LinkedIn: nanobio-corporation

BlueWillow Biologics, Inc. is a clinical-stage biotechnology firm based in Ann Arbor, Michigan. Founded in 2000, the company has developed a proprietary intranasal adjuvant and antigen delivery platform that aims to enhance vaccine efficacy and safety. Their technology utilizes oil-in-water emulsion droplets to facilitate a robust immune response, making it suitable for a variety of vaccine candidates. BlueWillow has conducted multiple clinical trials, demonstrating the safety of their platform in over 400 human subjects. Their product pipeline includes vaccines targeting anthrax and COVID-19, showcasing their commitment to addressing significant public health challenges. The company collaborates with various healthcare providers and organizations to advance their innovative vaccine solutions, contributing to the broader pharmaceutical manufacturing industry.

15. Boiron Italy

• Website: boiron.it
• Ownership type: Private
• Headquarters: Milan, Michigan, United States (USA)
• Employee distribution: Italy 90%, France 4%, Other 6%
• Founded year: 1979
• Headcount: 51-200
• LinkedIn: boiron-italia

Boiron Italy, established in 1979, is a private pharmaceutical company based in Milan, Michigan. It specializes in homeopathic medicines, providing a broad array of products that include granules, homeopathic specialties, cosmetics, dietary supplements, and medical devices. The company serves both individual consumers seeking alternative health solutions and healthcare professionals looking for complementary treatment options. Boiron Italy operates with a strong commitment to quality and innovation, ensuring that its products meet high standards. With a workforce primarily located in Italy, the company has expanded its reach to approximately 50 countries worldwide, reflecting its international presence and influence in the homeopathic sector. Boiron's dedication to research and development, along with its historical expertise in homeopathy, positions it as a significant player in the pharmaceutical manufacturing industry, particularly in the niche of alternative medicine.

16. Elba Laboratories

• Website: elba-labs.com
• Ownership type: Private
• Headquarters: Troy, Michigan, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1982
• Headcount: 11-50
• LinkedIn: elba-laboratories_2

Elba Laboratories, founded in 1982 and based in Troy, Michigan, operates as a private contract manufacturer specializing in personal care and pharmaceutical products. With a workforce of approximately 43 employees, the company has carved out a niche in the development and manufacturing of topical and oral formulations. Elba offers a comprehensive suite of services that includes product development, compounding, filling, and quality control, ensuring that their clients' products meet stringent safety and efficacy standards. Their facilities are registered with the FDA as a Current Good Manufacturing Practices (cGMP) facility, underscoring their commitment to high-quality production processes. Elba's expertise spans various industries, including skincare, oral care, and veterinary products, making them a versatile partner for businesses seeking to bring innovative health solutions to market.

17. DSC Laboratories, Inc.

• Website: dsclab.com
• Ownership type: Private
• Headquarters: Muskegon, Michigan, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1983
• Headcount: 11-50
• LinkedIn: dsc-labs-pharma

DSC Laboratories, Inc., based in Muskegon, Michigan, is a contract manufacturer that specializes in the formulation, manufacturing, and packaging of over-the-counter (OTC) pharmaceuticals and cosmetics. Established in 1983, the company operates within a cGMP facility, ensuring that all products meet stringent quality standards. DSC Laboratories offers a range of services, including technical assistance, product development, and laboratory services, which support clients in efficiently bringing their products to market. The company has a strong focus on quality and innovation, with capabilities that include the manufacturing of creams, liquids, and suppositories. Their expertise in reverse engineering allows them to assist clients in both existing product transfers and new product launches. DSC Laboratories serves a variety of customers, including national retailers and medical supply distributors, showcasing their ability to cater to different segments of the market. With a dedicated team and a commitment to superior service, DSC Laboratories continues to play a significant role in the pharmaceutical manufacturing industry.

18. ONL Therapeutics

• Website: onltherapeutics.com
• Ownership type: Venture Capital
• Headquarters: Ann Arbor, Michigan, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: Series D, $65.0M, September 2024
• Founded year: 2011
• Headcount: 1-10
• LinkedIn: onl-therapeutics

ONL Therapeutics, based in Ann Arbor, Michigan, is a clinical-stage biopharmaceutical company dedicated to developing innovative therapeutics for retinal diseases. Founded in 2011, the company is focused on addressing critical issues in vision loss through its lead product, ONL1204, which is designed to inhibit the Fas receptor, thereby protecting retinal cells from death and inflammation. This approach targets conditions such as geographic atrophy associated with age-related macular degeneration and open-angle glaucoma. ONL Therapeutics has made significant progress in clinical trials, with ongoing studies demonstrating the potential efficacy of ONL1204. The company has recently raised $65 million in Series D funding, which underscores its commitment to advancing its pipeline and addressing the needs of patients suffering from vision-threatening conditions.

19. Grand River Aseptic Manufacturing

• Website: grandriverasepticmfg.com
• Ownership type: Private Equity
• Headquarters: Grand Rapids, Michigan, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: November 2017
• Founded year: 2011
• Headcount: 201-500
• LinkedIn: grand-river-aseptic-manufacturing

Grand River Aseptic Manufacturing (GRAM), based in Grand Rapids, Michigan, is a pharmaceutical manufacturer that specializes in aseptic filling and finishing services for sterile injectables. Established in 2011, the company has carved out a significant role in the pharmaceutical industry by providing essential services that include analytical testing and regulatory filing support. GRAM's facilities are equipped with advanced technology and modern equipment, enabling them to handle a variety of products, including liquid and lyophilized vials, syringes, and cartridges. Their expertise extends to the manufacturing of biologics, small molecules, and controlled substances, ensuring compliance with stringent regulatory standards. The company emphasizes quality processes and has a dedicated team focused on continuous improvement, which is crucial in maintaining high standards in pharmaceutical production. GRAM's operations are fully compliant with current Good Manufacturing Practices (cGMP), making them a reliable partner for pharmaceutical clients looking to navigate the complexities of drug manufacturing and delivery.

Pharmaceutical Manufacturing Insights: Key Companies in Michigan

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