Biomedical engineering in Alabama consists of companies that design, develop, and manufacture medical devices and related technologies. This sector includes various specialties such as surgical instruments, rehabilitation equipment, and diagnostic tools. As the demand for innovative healthcare solutions continues to rise, Alabama is poised for growth with companies pushing forward new technologies, emphasizing cost-effective solutions, and improving patient outcomes. Interesting trends show an increasing focus on biotechnology and personalized medicine, which presents exciting opportunities for collaboration and investment within the state’s flourishing biomedical ecosystem.


The listed companies range in size from small firms to substantial operations with hundreds of employees. They include entities like Synovis Micro Companies Alliance, founded in 2001, specializing in microsurgery products, and Avanti Research, known for lipid research and drug delivery solutions, founded in 1969. Predominantly located across Birmingham, Huntsville, and Auburn, these companies reflect a mixture of privately owned and venture-backed enterprises with foundational years spanning several decades. Their specializations highlight innovative advancements in medical devices and biotechnology, making Alabama an emerging hub in this sector.


Read on to explore top biomedical engineering companies operating in Alabama.


Top 19 Biomedical Engineering Companies in Alabama


1. Synovis Micro Companies Alliance, Inc.


Synovis Micro Companies Alliance, Inc., based in Birmingham, Alabama, is a private medical device manufacturer founded in 2001. The company specializes in creating products for microsurgery, particularly focusing on nerve repair and regeneration. Their extensive range of surgical instruments includes flow couplers, microvascular clamps, microsutures, and various specialized tools designed to assist surgeons in delicate procedures. Synovis is dedicated to enhancing surgical outcomes and improving patient care through innovative solutions. They serve healthcare professionals and surgeons, ensuring that their products meet the high standards required in the medical field. As a subsidiary of Baxter International Inc., Synovis benefits from a broader network while maintaining a focused approach to microsurgical advancements.


2. Fitz-Thors Industries

  • Website: fitz-thors.com
  • Ownership type: Private
  • Headquarters: Bessemer, Alabama, United States (USA)
  • Employee distribution: United States (USA) 100%
  • Founded year: 2007
  • Headcount: 11-50
  • LinkedIn: fitz-thors-engineering

Fitz-Thors Industries, based in Bessemer, Alabama, is a private engineering and manufacturing firm founded in 2007. The company specializes in product development and medical device manufacturing, providing a full suite of services from initial design to final production. Fitz-Thors operates an FDA-registered facility and is ISO 13485:2016 certified, ensuring compliance with stringent industry standards for medical devices. Their expertise includes in-house design, engineering, prototyping, and contract manufacturing, particularly for precision medical instruments and devices. Fitz-Thors serves a variety of clients, including startups and established companies, helping them navigate the complexities of bringing medical products to market. Their commitment to quality and efficiency in manufacturing processes supports their clients' needs for timely and compliant product launches.


3. Curiteva, Inc.

  • Website: curiteva.com
  • Ownership type: Venture Capital
  • Headquarters: Tanner, Alabama, United States (USA)
  • Employee distribution: United States (USA) 100%
  • Latest funding: $4.0M, January 2024
  • Founded year: 2018
  • Headcount: 51-200
  • LinkedIn: curiteva

Curiteva, Inc. is a medical device manufacturer based in Tanner, Alabama, established in 2018. The company focuses on innovative solutions for spinal surgery, offering a range of products that include interbody fusion systems and bone graft materials. These products are designed to improve surgical outcomes for healthcare providers, particularly surgeons and medical facilities involved in spinal procedures. Curiteva has recently launched its Inspire® Posterior Interbody Solutions and has surpassed 1,000 procedures with its Inspire Cervical Trabecular PEEK™ technology. The company has also received FDA clearance for several of its products, showcasing its commitment to regulatory compliance and safety in medical devices. With a workforce of 51-200 employees and recent funding of $4 million in January 2024, Curiteva is positioned for growth and innovation in the biomedical engineering field.


4. BioHorizons

  • Website: biohorizons.com
  • Ownership type: Private
  • Headquarters: Birmingham, Alabama, United States (USA)
  • Employee distribution: United States (USA) 79%, Canada 5%, Italy 4%, Other 13%
  • Latest funding: $1.5M, December 2012
  • Founded year: 1994
  • Headcount: 201-500
  • LinkedIn: biohorizons

BioHorizons, founded in 1994 and based in Birmingham, Alabama, is a private company that specializes in the manufacture of dental implants, prosthetics, and biologics. With a workforce of approximately 476 employees, BioHorizons serves dental professionals by providing high-quality products designed to enhance dental procedures and improve patient outcomes. Their product range includes various types of dental implants, advanced prosthetic techniques, and biologics for tissue regeneration, such as bone grafting materials and membranes. The company also offers digital solutions for guided surgery and has a strong educational component, providing training and resources for dental professionals. BioHorizons operates primarily in the dental and medical device industries, with a notable presence in North America and select international markets.


5. Nidek Medical India Pvt Ltd


Nidek Medical India Pvt Ltd, based in Birmingham, Alabama, is a private medical device manufacturer that specializes in respiratory care products, particularly oxygen concentrators. Founded in 1986, the company has established itself as a key player in the production of high-quality oxygen therapy devices. Their product lineup includes models like the Nuvo Lite, Nuvo 8, Nuvo 10, and the Max 30, which are designed for various healthcare settings. Nidek Medical is dedicated to innovation and patient care, ensuring that their products are not only effective but also user-friendly. The company operates globally, distributing its products to over 120 countries, and is committed to maintaining high standards, as evidenced by their ISO 13485:2016 certification. Nidek Medical has also been recognized for its contributions to the industry, receiving awards such as the Alabama Medium Manufacturer of the Year and the President’s “E” Star Award for export achievements.


6. Aptar CSP Technologies

  • Website: csptechnologies.com
  • Ownership type: Private
  • Headquarters: Auburn, Alabama, United States (USA)
  • Employee distribution: United States (USA) 71%, France 23%, Other 6%
  • Latest funding: Other (Grant), $19.3M, October 2021
  • Founded year: 1928
  • Headcount: 501-1000
  • LinkedIn: aptar-csp-technologies

Aptar CSP Technologies, based in Auburn, Alabama, is a material science company that has been operational since 1928. The firm specializes in active packaging solutions tailored for the healthcare and food industries. Their offerings include a wide range of services such as feasibility assessments, product development, and regulatory support, aimed at pharmaceutical and food producers. This support helps clients enhance product stability and safety, which is critical in the biomedical field. Aptar CSP Technologies has a strong emphasis on innovation, with over 500 patents granted worldwide, and they reinvest 5% of their annual revenue into sustainability and research and development projects. The company operates multiple production sites across the globe, including locations in France and Japan, and serves various markets, including oral solid doses, medical devices, and diagnostics.


7. Arab Engineers Co. for Designs and Medical Instrumentation

  • Website: arabengineersdmi.com
  • Ownership type: Private
  • Headquarters: Cairo, Alabama, United States (USA)
  • Employee distribution: Egypt 100%
  • Founded year: 2018
  • Headcount: 11-50
  • LinkedIn: arab-engineers-dmi

Arab Engineers Co. for Designs and Medical Instrumentation is a Cairo-based private company that specializes in the design and manufacture of medical devices, particularly surgical instruments for maxillofacial and neurosurgery. Established in 2016 by a group of university professors and engineers, the company aims to provide high-quality, affordable medical supplies tailored to the needs of healthcare professionals. Their product range includes customized plates, total mandibular joints, and various distractors, all designed to meet international quality standards. The company operates primarily in Egypt and is dedicated to addressing local demands for medical supplies, thereby contributing to the national healthcare landscape. Their commitment to innovation and quality positions them as a significant player in the biomedical engineering field.


8. RAMPART ic

  • Website: rampartic.com
  • Ownership type: Private
  • Headquarters: Birmingham, Alabama, United States (USA)
  • Employee distribution: United States (USA) 100%
  • Latest funding: $3.1M, September 2020
  • Founded year: 2014
  • Headcount: 11-50
  • LinkedIn: rampart-ic

RAMPART ic, founded in 2014 and based in Birmingham, Alabama, is a private medical device manufacturer specializing in radiation protection solutions tailored for interventional cardiologists and their teams. The company has developed innovative products like the Rampart M1128 and L148, which are designed to enhance safety and comfort during medical procedures. Unlike traditional lead aprons that can cause fatigue and serious injuries over time, RAMPART ic's products provide full-bodied radiation protection without the associated drawbacks. The company has received funding amounting to approximately $3.1 million as of September 2020, indicating investor confidence in their mission to improve working conditions for healthcare professionals. RAMPART ic's commitment to addressing the challenges faced by interventionalists positions it as a relevant player in the biomedical engineering sector, focusing on both safety and efficiency in medical environments.


9. GeneCapture, Inc.

  • Website: genecapture.com
  • Ownership type: Venture Capital
  • Headquarters: Huntsville, Alabama, United States (USA)
  • Employee distribution: United States (USA) 100%
  • Latest funding: Other (Grant), March 2023
  • Founded year: 2009
  • Headcount: 11-50
  • LinkedIn: genecapture-inc.

GeneCapture, Inc., founded in 2009 and based in Huntsville, Alabama, is a biotechnology firm dedicated to advancing rapid diagnostics for infectious diseases. The company has developed the CAPTURE Platform, a portable technology that enables quick identification of pathogens and testing for antibiotic susceptibility. This platform is designed for use in various settings, including clinics, military operations, and rural healthcare environments, where timely diagnosis is crucial. GeneCapture's technology is particularly significant in the face of rising antimicrobial resistance, as it allows healthcare providers to make informed treatment decisions swiftly. The company has received multiple awards and grants, including significant funding from the Department of Defense, which underscores its commitment to addressing urgent health needs. GeneCapture's innovative approach and focus on point-of-care testing position it as a notable player in the biomedical engineering sector.


10. Rehab Technologies, LLC

  • Website: rtllc.us
  • Ownership type: Private
  • Headquarters: Huntsville, Alabama, United States (USA)
  • Employee distribution: United States (USA) 100%
  • Founded year: 1997
  • Headcount: 11-50
  • LinkedIn: rehab-technologies-llc

Rehab Technologies, LLC, established in 1997 and based in Huntsville, Alabama, is a medical equipment provider that specializes in rehabilitation products designed for patients recovering at home. The company offers a range of products, including Continuous Passive Motion devices, Negative Pressure Wound Therapy products, and Spinal Orthotic Devices. With a focus on delivering personalized support, Rehab Technologies ensures a smooth transition for patients moving from hospital care to home care. They serve a broad area across the Southeast United States, including Alabama, Georgia, Tennessee, Louisiana, Florida, and Mississippi. The company prides itself on its customer service, providing same-day delivery and in-home training to enhance patient experience and satisfaction. Rehab Technologies is fully licensed, insured, and accredited by the Accreditation Commission for Health Care (ACHC), which underscores their commitment to quality and compliance in the medical equipment industry.


11. Proteus Genomics

  • Website: plabs.com
  • Ownership type: Private
  • Headquarters: Birmingham, Alabama, United States (USA)
  • Employee distribution: United States (USA) 100%
  • Founded year: 2015
  • Headcount: 51-200
  • LinkedIn: proteus-genomics

Proteus Genomics is a private healthcare laboratory based in Birmingham, Alabama, founded in 2015. The company specializes in molecular diagnostics and genomic testing, providing a range of advanced testing services that include COVID-19, respiratory infections, urinary tract infections (UTIs), sexually transmitted infections (STIs), and women's health tests. Their primary clientele consists of healthcare providers who depend on accurate and rapid diagnostic results to guide patient care. Proteus Genomics operates with a mission centered on precision-guided, patient-focused healthcare solutions. They utilize high-complexity CLIA-certified laboratory techniques, including real-time quantitative reverse transcription polymerase chain reaction (RT qRT-PCR) and next-generation DNA sequencing (NGS). Their proprietary test panels are designed to deliver actionable results, enhancing treatment visibility for healthcare providers. The company emphasizes quality, innovation, and efficiency in its services, aiming to improve clinical and economic outcomes for patients and healthcare systems alike.


12. CFD Research Corporation

  • Website: cfd-research.com
  • Ownership type: Private
  • Headquarters: Huntsville, Alabama, United States (USA)
  • Employee distribution: United States (USA) 99%, Other 1%
  • Latest funding: Other (Grant), August 2023
  • Founded year: 1987
  • Headcount: 201-500
  • LinkedIn: cfd-research-corporation

CFD Research Corporation, founded in 1987 and based in Huntsville, Alabama, is a private engineering firm that specializes in advanced simulations and prototypes across various industries, including aerospace, defense, and life sciences. The company employs a workforce of over 300, with a significant portion holding advanced degrees. CFD Research is known for its innovative approach to research and development, focusing on reducing risks and costs for both government and commercial clients. Their capabilities extend to software development and experimental tools that support systems engineering and design. In the biomedical sector, CFD Research has developed products like the Nasal Cavity Phantoms and SynVivo, which are instrumental in medical research and drug discovery. The company has received recognition for its work, including multiple awards for excellence in the Small Business Innovation Research (SBIR) program. Their commitment to community involvement and collaboration with research organizations further underscores their role in advancing technology in life sciences.


13. Circulogene

  • Website: circulogene.com
  • Ownership type: Private
  • Headquarters: Birmingham, Alabama, United States (USA)
  • Employee distribution: United States (USA) 100%
  • Latest funding: Other (Debt), $2.0M, March 2023
  • Founded year: 2015
  • Headcount: 11-50
  • LinkedIn: circulogene-diagnostics

Circulogene, founded in 2015 and based in Birmingham, Alabama, is a biotechnology firm that focuses on liquid biopsy and cancer diagnostics. The company offers a range of innovative testing solutions designed to assist oncologists in personalizing treatment plans for cancer patients. Their products include TumorClear, which utilizes next-generation sequencing to identify actionable mutations, ImmunoClear, the only plasma cfRNA PD-L1 test, and MSI Complete, which enhances the detection of microsatellite instability. Circulogene's approach aims to improve patient outcomes by providing comprehensive molecular profiles that guide treatment decisions. The company has served over 25,000 cancer patients, showcasing its impact in the field. Recently, Circulogene secured $2 million in funding, reflecting confidence in its technology and growth trajectory.


14. XO Armor Technologies Inc.

  • Website: xoarmortech.com
  • Ownership type: Venture Capital
  • Headquarters: Auburn, Alabama, United States (USA)
  • Employee distribution: United States (USA) 100%
  • Latest funding: Seed, $1.9M, April 2023
  • Founded year: 2019
  • Headcount: 11-50
  • LinkedIn: xo-armor-technologies-inc

XO Armor Technologies Inc., founded in 2019 and based in Auburn, Alabama, specializes in custom protective solutions utilizing advanced 3D scanning and printing technology. The company caters to various sectors, including healthcare, sports, and emergency services, by providing tailored protective gear designed to enhance safety and performance. Their innovative technology allows for on-site printing of custom devices, which significantly improves patient care and athlete performance. XO Armor's solutions are particularly beneficial for first responders and military personnel, enabling them to receive immediate, high-quality protective gear in challenging environments. The company has recently secured $1.92 million in seed funding, reflecting investor confidence in their potential to revolutionize protective equipment in the biomedical field.


15. iRepertoire, Inc.

  • Website: irepertoire.com
  • Ownership type: Private
  • Headquarters: Huntsville, Alabama, United States (USA)
  • Employee distribution: United States (USA) 100%
  • Founded year: 2009
  • Headcount: 11-50
  • LinkedIn: irepertoire-inc-

iRepertoire, Inc., founded in 2009 and based in Huntsville, Alabama, is a biotechnology firm that specializes in immune repertoire profiling and sequencing technologies. The company provides a range of services and products designed to assist researchers in the biotechnology and pharmaceutical sectors. Their advanced technologies, including arm-PCR and dam-PCR, enable comprehensive immune profiling, which is crucial for understanding immune responses and developing new therapies. iRepertoire's offerings include bulk immune repertoire services, single-cell V(D)J sequencing, and bioinformatics support, catering to various applications such as immuno-oncology, autoimmune diseases, and infectious diseases. The company positions itself as a partner for clinical and translational research, providing expert support from trial planning to data analysis. With a dedicated team of scientists, iRepertoire aims to facilitate breakthroughs in immune biology and therapeutic development.


16. MRIMath

  • Website: mrimath.com
  • Ownership type: Corporate
  • Headquarters: Birmingham, Alabama, United States (USA)
  • Employee distribution: United States (USA) 71%, Lebanon 29%
  • Latest funding: Other (Grant), March 2023
  • Founded year: 2019
  • Headcount: 11-50
  • LinkedIn: mrimath

MRIMath, founded in 2019 and based in Birmingham, Alabama, is a healthcare technology firm that specializes in artificial intelligence-driven solutions for medical imaging. The company focuses on providing advanced tools for tumor segmentation and volumetric analysis, primarily targeting healthcare professionals, clinics, and researchers. Their platform is designed to enhance collaboration and efficiency in patient care, allowing users to access and share imaging data securely. MRIMath's product offerings include AI-powered segmentation tools for glioblastoma and metastatic brain tumors, as well as a collaborative environment for medical teams. The company has received FDA approval for some of its products, underscoring its commitment to regulatory compliance and quality in healthcare technology.


17. Laysan Bio, Inc.

  • Website: laysanbio.com
  • Ownership type: Private
  • Headquarters: Arab, Alabama, United States (USA)
  • Employee distribution: United States (USA) 100%
  • Founded year: 2006
  • Headcount: 11-50
  • LinkedIn: laysan-bio-inc.

Laysan Bio, Inc., founded in 2006 and based in Arab, Alabama, is a private biotechnology company that specializes in drug delivery systems. The company focuses on providing activated polyethylene glycol (PEG) products, which are essential for various therapeutic applications. Laysan Bio serves a clientele that includes academic institutions, research centers, and biotech firms, offering both catalog and custom PEG reagents to support drug development and research initiatives. The company has a robust manufacturing facility that adheres to FDA regulations, allowing them to produce compliant bulk pharmaceutical chemicals. Their team has extensive experience in the development and supply of PEG reagents, having contributed to several FDA and EU approved drug products. This experience positions Laysan Bio as a knowledgeable partner in the drug development process, emphasizing their commitment to quality and technical support for their customers.


18. Avanti Polar Lipids

  • Website: avantilipids.com
  • Ownership type: Corporate
  • Headquarters: Alabaster, Alabama, United States (USA)
  • Latest funding: $185.0M, July 2020
  • Founded year: 1969
  • Headcount: 201-500
  • LinkedIn: avanti-polar-lipids-inc-

Avanti Polar Lipids, now known as Avanti Research, is a life sciences company based in Alabaster, Alabama. Founded in 1969, the company has built a reputation for providing high-purity lipids and lipid research tools. They cater primarily to researchers in the pharmaceutical and biotechnology sectors, focusing on drug delivery systems and lipidomics. Avanti offers a range of services, including cGMP manufacturing and custom synthesis, which are essential for developing effective therapeutic solutions. Their products support various applications, such as nucleic acid delivery and protein delivery, which are critical in modern biomedical research. In 2020, Avanti received significant funding, amounting to $185 million, which underscores their relevance and potential in the industry. The company continues to evolve, expanding its product offerings and maintaining a strong commitment to quality and innovation in lipid research.


19. Avans Machine INC

  • Website: avansmac.com
  • Ownership type: Family Owned
  • Headquarters: Scottsboro, Alabama, United States (USA)
  • Employee distribution: United States (USA) 100%
  • Founded year: 1989
  • Headcount: 11-50
  • LinkedIn: avans-machine-inc

Avans Machine INC, founded in 1989 and based in Scottsboro, Alabama, is a family-owned precision machining company. With a workforce of around 65 employees, they operate from a 50,000 square foot facility equipped with advanced machining technology. The company specializes in CNC machining and produces high-quality components for various sectors, including aerospace, defense, and notably, medical instruments and implants. Their commitment to quality is underscored by their AS9100D and ISO 9001:2015 certifications, ensuring that their products meet stringent industry standards. Avans Machine serves a range of clients, including major organizations like NASA and Lockheed Martin, and has a strong focus on customer satisfaction and precision in manufacturing. Their capabilities include close tolerance assemblies and machining of exotic materials, making them a valuable player in the biomedical engineering field.



Biomedical Engineering Insights: Key Companies in Alabama


CompanyHeadquarterSizeFoundedOwnership
Synovis Micro Companies Alliance, Inc.Birmingham, Alabama, United States (USA)11-502001Private
Fitz-Thors IndustriesBessemer, Alabama, United States (USA)11-502007Private
Curiteva, Inc.Tanner, Alabama, United States (USA)51-2002018Venture Capital
BioHorizonsBirmingham, Alabama, United States (USA)201-5001994Private
Nidek Medical India Pvt LtdBirmingham, Alabama, United States (USA)1001-50001986Private
Aptar CSP TechnologiesAuburn, Alabama, United States (USA)501-10001928Private
Arab Engineers Co. for Designs and Medical InstrumentationCairo, Alabama, United States (USA)11-502018Private
RAMPART icBirmingham, Alabama, United States (USA)11-502014Private
GeneCapture, Inc.Huntsville, Alabama, United States (USA)11-502009Venture Capital
Rehab Technologies, LLCHuntsville, Alabama, United States (USA)11-501997Private
Proteus GenomicsBirmingham, Alabama, United States (USA)51-2002015Private
CFD Research CorporationHuntsville, Alabama, United States (USA)201-5001987Private
CirculogeneBirmingham, Alabama, United States (USA)11-502015Private
XO Armor Technologies Inc.Auburn, Alabama, United States (USA)11-502019Venture Capital
iRepertoire, Inc.Huntsville, Alabama, United States (USA)11-502009Private
MRIMathBirmingham, Alabama, United States (USA)11-502019Corporate
Laysan Bio, Inc.Arab, Alabama, United States (USA)11-502006Private
Avanti Polar LipidsAlabaster, Alabama, United States (USA)201-5001969Corporate
Avans Machine INCScottsboro, Alabama, United States (USA)11-501989Family Owned


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