The physical therapy and rehabilitation industry in the US plays a crucial role in helping patients recover from injuries and surgeries. It encompasses a range of services, including outpatient clinics, home health care, and specialized rehabilitation centers. Companies in this space offer personalized therapy programs designed to improve mobility, strength, and overall health. Innovative technologies, such as telehealth and wearable devices, are shaping the future of the industry, making treatment more accessible and efficient. With a growing aging population and increasing awareness about the importance of rehabilitation, this sector is expected to see significant growth in the coming years.


The list of investors in the physical therapy and rehabilitation sector is a mix of venture capital firms and corporate entities. While many are headquartered in major innovation hubs like San Francisco and New York, they vary in size—ranging from small firms to large investment funds. Established over different decades, these investors collectively made 1,500 deals in 2024, reflecting strong interest in healthcare technology and rehabilitation solutions. Their strategic support is pivotal in advancing startups in this essential industry, ensuring innovation and quality care for patients.


Top 17 Physical Therapy and Rehabilitation Investors in the US


1. Y Combinator

  • Website: ycombinator.com
  • Type: Venture Capital
  • Headquarters: San Francisco, California, United States (USA)
  • Founded year: 2005
  • Headcount: 51-200
  • Number of deals in 2024: 802
  • LinkedIn: y-combinator

Y Combinator is a prominent startup accelerator and venture capital firm based in San Francisco, California, founded in 2005. It provides funding and mentorship to early-stage technology companies, helping entrepreneurs launch and grow their businesses through structured programs, resources like the Startup School, and co-founder matching services. Y Combinator has successfully launched over 4,000 startups, establishing itself as a key player in the technology startup ecosystem. Among their notable investments, they have funded several companies relevant to the healthcare sector, including Shasta Health, which raised $500,000 in a Pre-Seed round in August 2023, and Comet Healthcare, which raised $125,000 in a Pre-Seed round in August 2021. Additionally, Flowly, another healthcare-related startup, also received $125,000 in a Pre-Seed round in August 2021. Kivo Health raised $500,000 in March 2023, and EncepHeal Therapeutics secured $150,000 in a Seed round in August 2019. These transactions highlight Y Combinator's engagement with startups that could potentially impact physical therapy and rehabilitation, showcasing their interest in the healthcare domain.


2. Government of Canada

  • Website: canada.ca
  • Type: Corporate
  • Headquarters: Canada, Kentucky, United States (USA)
  • Founded year: 1999
  • Headcount: 10001+
  • Number of deals in 2024: 137
  • LinkedIn: government-of-canada

The Government of Canada is a public entity that provides a wide range of services and information to Canadian citizens and residents, addressing various needs including employment, immigration, health care, and taxation. Founded in 1999, it operates through multiple departments and agencies to ensure access to essential services and support for individuals and businesses across the country. In 2023, the Government of Canada has been involved in several significant transactions within the physical therapy and rehabilitation sector, including grants to NewU Physio, Brain Care Centre, and Abilities Centre. These grants reflect the government's commitment to enhancing health care services and supporting organizations that focus on rehabilitation and physical therapy, thereby contributing to the overall well-being of Canadians.


3. MedTech Innovator

  • Website: medtechinnovator.org
  • Type: Corporate
  • Headquarters: Los Angeles, California, United States (USA)
  • Founded year: 2013
  • Headcount: 11-50
  • Number of deals in 2024: 85
  • LinkedIn: medtech-innovator

MedTech Innovator is a not-for-profit organization based in Los Angeles, California, founded in 2013. It serves as the largest accelerator for medical technology companies, offering accelerator programs, mentorship, and competitions to support startups in the medical device, digital health, and diagnostics sectors. Among its notable transactions, MedTech Innovator has supported NeuroRecovery Technologies, which focuses on rehabilitation solutions, and has provided non-equity assistance to various companies like Alyve Medical and MicroTransponder. These activities highlight their commitment to fostering innovation in healthcare, including physical therapy and rehabilitation technologies.


4. StartUp Health

  • Website: startuphealth.com
  • Type: Venture Capital
  • Headquarters: New York, New York, United States (USA)
  • Founded year: 2011
  • Headcount: 11-50
  • LinkedIn: startuphealth

StartUp Health is a not-for-profit organization based in New York, focused on health innovation. Founded in 2011, it supports health entrepreneurs and startups through its Health Moonshot Communities, providing resources, networking, and media content to tackle significant health challenges. StartUp Health has been involved in various transactions, including investments in companies like Joint Academy, which raised funds in 2015 and focuses on musculoskeletal health, and CNS Therapy, which raised funds in 2015 and is involved in therapeutic solutions. Additionally, they invested in GoodLife Technology and MediSeen, both of which contribute to health technology innovation. Their offerings include newsletters, podcasts, and a journal that highlight progress in health technology and innovation, making them a key player in the health investment landscape.


5. OrbiMed

  • Website: orbimed.com
  • Type: Venture Capital
  • Headquarters: New York, New York, United States (USA)
  • Founded year: 1989
  • Headcount: 51-200
  • Number of deals in 2024: 52
  • LinkedIn: orbimed-advisors

OrbiMed is a prominent investment firm based in New York, specializing in healthcare investments. Founded in 1989, the firm manages approximately $17 billion in assets across various investment strategies, focusing on biopharmaceuticals, medical devices, and healthcare services. In recent transactions, OrbiMed has participated in funding rounds for companies such as Koya Medical, which is involved in healthcare services, and Crossover Health, a tech-enabled healthcare organization. These investments highlight OrbiMed's commitment to driving innovation in the healthcare sector, which may include physical therapy and rehabilitation services. Their diverse portfolio and active engagement in healthcare investments position them as a relevant player in the physical therapy and rehabilitation space.


6. New Enterprise Associates (NEA)

  • Website: nea.com
  • Type: Venture Capital
  • Headquarters: Menlo Park, California, United States (USA)
  • Founded year: 1977
  • Headcount: 51-200
  • Number of deals in 2024: 57
  • LinkedIn: new-enterprise-associates

New Enterprise Associates (NEA) is a venture capital firm founded in 1977, based in Menlo Park, California. NEA specializes in investment management and advisory services for startups, particularly in the technology and healthcare sectors. The firm partners with entrepreneurs to provide funding and strategic guidance, emphasizing long-term relationships with founders. NEA has been involved in several significant transactions in the healthcare space, including investments in Vori Health, which focuses on musculoskeletal care and has raised substantial funding through Series A and Series B rounds. This involvement highlights NEA's commitment to supporting innovative solutions in physical therapy and rehabilitation, alongside their broader healthcare investment strategy.


7. Deep Tech Fund (an Alumni Ventures Fund)

  • Website: av.vc
  • Type: Venture Capital
  • Headquarters: Manchester, New Hampshire, United States (USA)
  • Founded year: 2023
  • Headcount: 51-200
  • Number of deals in 2024: 258
  • LinkedIn: deep-tech-fund-av-focused-fund

Deep Tech Fund (an Alumni Ventures Fund) is a venture capital firm based in Manchester, New Hampshire, founded in 2023. It provides accredited investors and institutions with access to professionally-managed, diversified venture portfolios, leveraging a network of over 10,000 investors to connect them with high-quality investment opportunities in the startup ecosystem. The fund has been active in the healthcare sector, with notable investments including WelbeHealth, which raised $30 million in Series C funding in February 2020 and $15 million in Series B funding in June 2018, both of which are relevant to physical therapy and rehabilitation services. Additionally, the fund invested $50 million in Cala Health in December 2024, a company focused on neuromodulation therapies that can aid in rehabilitation. These transactions highlight the fund's engagement in the healthcare and rehabilitation sectors, reinforcing its relevance in this space.


8. Silicon Valley Bank

  • Website: svb.com
  • Type: Venture Capital
  • Headquarters: Santa Clara, California, United States (USA)
  • Founded year: 1983
  • Headcount: 5001-10000
  • Number of deals in 2024: 31
  • LinkedIn: silicon-valley-bank

Silicon Valley Bank is a commercial bank founded in 1983, located in Santa Clara, California, specializing in providing financial services to the innovation economy, particularly tech startups and venture capital firms. They offer a range of products including business banking, global payments, and asset management, helping clients navigate financial challenges and support their growth. In the context of physical therapy and rehabilitation, Silicon Valley Bank has been involved in several significant transactions, including providing $15 million in debt financing to AlterG, a company known for its anti-gravity treadmill technology used in rehabilitation. They also financed Clinicient with $7 million, a company that offers software solutions for physical therapy practices, and Miach Orthopaedics, which raised $10 million for its innovative orthopedic solutions. These investments highlight their commitment to supporting companies that contribute to the physical therapy and rehabilitation industry.


9. Plug and Play Tech Center


Plug and Play Tech Center is an innovation hub and venture capital firm based in Sunnyvale, California, founded in 2006. They connect startups with corporations to foster growth and innovation, offering various programs including accelerator initiatives and investment opportunities. In 2024 alone, they made 253 investments, showcasing their active role in the venture capital landscape. Among their notable transactions, they have invested in health-related startups such as Anonymous Health, which raised funds in a Seed Round in November 2024, and Ciba Health, a virtual healthcare platform focused on chronic conditions. These investments highlight their interest in health technology, which could encompass areas relevant to physical therapy and rehabilitation.


10. Perceptive Advisors


Perceptive Advisors is a New York-based venture capital firm founded in 1999, specializing in the life sciences sector. The firm provides capital solutions and investment management services to both private and public healthcare companies, with a strong focus on biotechnology, pharmaceuticals, and medical devices. Their expertise aids clients in securing funding for innovation and growth within the healthcare industry. Notably, Perceptive Advisors has participated in significant funding rounds for companies relevant to physical therapy and rehabilitation, such as Mainstay Medical, which raised $125 million to commercialize the ReActiv8 system, a device aimed at treating chronic pain through rehabilitation. They also invested in Omada Health, a chronic care provider that integrates healthcare solutions, which may include rehabilitation services. These transactions highlight their active role in supporting innovations that can impact physical therapy and rehabilitation.


11. Gaingels

  • Website: gaingels.com
  • Type: Venture Capital
  • Headquarters: Burlington, Vermont, United States (USA)
  • Founded year: 2015
  • Headcount: 11-50
  • Number of deals in 2024: 60
  • LinkedIn: gaingels

Gaingels is a venture capital firm founded in 2015, based in Burlington, Vermont, dedicated to investing in companies with diverse leadership. The firm provides capital and support to startups, particularly those led by underrepresented groups, to foster diversity and inclusion in the innovation economy. Gaingels also offers scholarship programs and advisory services to enhance board diversity. Among their notable transactions, they participated in the funding of Swing Therapeutics, which closed a $10.3 million Series A funding round to support a clinical trial for a digital therapeutic aimed at treating fibromyalgia. This aligns with the physical therapy and rehabilitation context, as fibromyalgia often requires therapeutic interventions. Additionally, their involvement in Heading Health, a mental healthcare provider, further demonstrates their engagement in the broader healthcare sector, which can include rehabilitation services.


12. Polaris Partners

  • Website: polarispartners.com
  • Type: Venture Capital
  • Headquarters: Boston, Massachusetts, United States (USA)
  • Founded year: 1996
  • Headcount: 11-50
  • Number of deals in 2024: 19
  • LinkedIn: polaris-partners

Polaris Partners is a venture capital firm based in Boston, Massachusetts, founded in 1996. The firm specializes in healthcare and biotechnology investments, partnering with entrepreneurs to provide funding and strategic guidance to help them innovate and grow their businesses. Polaris has a diverse portfolio that includes companies focused on transformative healthcare solutions. Notably, they led a $12 million Series A funding round for SpineZone, a provider of personalized treatment for musculoskeletal conditions, which is directly relevant to physical therapy. Additionally, they participated in funding rounds for Livara Health, which is expanding its technology and clinical capabilities to meet growing healthcare needs. These transactions highlight Polaris Partners' active role in supporting companies that contribute to the physical therapy and rehabilitation industry.


13. General Catalyst


General Catalyst is a venture capital firm founded in 2000, based in San Francisco, California. The firm specializes in early-stage and growth investments, providing capital and strategic guidance to startups across various industries, including technology and healthcare. Notably, General Catalyst has made substantial investments in Sword Health, raising $163 million in a Series D round in November 2021 and $85 million in a Series C round in June 2021. These investments highlight their commitment to advancing digital solutions in physical therapy. Additionally, they have invested in Eleanor Health, which focuses on behavioral health, further demonstrating their engagement in the healthcare sector. Overall, General Catalyst's investment strategy reflects a strong interest in innovative healthcare solutions, including those relevant to physical therapy and rehabilitation.


14. F-Prime


F-Prime Capital is a venture capital firm based in Cambridge, Massachusetts, founded in 1946. The firm specializes in creating and investing in healthcare and technology companies, providing both venture capital investments and advisory services to entrepreneurs. F-Prime has a global presence and expertise that enables them to effectively support startups. Among their notable transactions, F-Prime participated in the Series A funding round for Spry, which raised over $7 million to enhance practice management for physical rehabilitation. Additionally, they were involved in Spry's Series B round, which raised $15 million in 2024. These investments highlight F-Prime's active role in the physical therapy and rehabilitation sector, alongside their broader healthcare focus.


15. Frazier Healthcare Partners


Frazier Healthcare Partners is a venture capital firm based in Seattle, Washington, specializing in healthcare and life sciences investments. Founded in 1991, the firm focuses on growth buyout investments in profitable healthcare businesses and innovative biopharmaceuticals. Their clients primarily include healthcare companies seeking capital to scale operations and enhance service offerings. Notably, Frazier has been involved in transactions such as The CORE Institute, which raised funds for orthopedic care, potentially linking them to the rehabilitation sector. While their other transactions, such as those with Zelos Therapeutics and Zeltiq Aesthetics, focus more on biopharmaceuticals and aesthetic treatments, the firm's overarching commitment to healthcare investments positions them as a potential player in the physical therapy and rehabilitation market.


16. GV (Google Ventures)

  • Website: gv.com
  • Type: Venture Capital
  • Headquarters: San Francisco Bay Area, California, United States (USA)
  • Founded year: 2009
  • Headcount: 51-200
  • Number of deals in 2024: 74
  • LinkedIn: gv

GV (Google Ventures) is a venture capital firm founded in 2009, based in the San Francisco Bay Area, with over $10 billion in assets under management. The firm specializes in funding and supporting innovative technology startups across various sectors, including life sciences and artificial intelligence. Notably, GV has invested in Synapticure, a teleneurology company that raised $25 million in Series A funding in November 2024, aimed at scaling its care platform for ALS patients. Additionally, they have invested in Cala Health, which raised $50 million in Series C funding in December 2024, focusing on developing therapies for neurological conditions. These investments highlight GV's active role in the healthcare sector, particularly in areas that intersect with physical therapy and rehabilitation.


17. Sosv

  • Website: sosv.com
  • Type: Venture Capital
  • Headquarters: United States (USA)
  • Founded year: 1995
  • Headcount: 51-200
  • Number of deals in 2024: 170
  • LinkedIn: sosv

Sosv is a venture capital firm founded in 1995, based in the United States, that specializes in funding and supporting deep tech startups through its development programs. The firm provides venture capital investment and resources to help startups grow and succeed in various sectors, including health and climate technology. Notably, Sosv has been involved in multiple transactions with Kinexcs, a company that has raised funds through various rounds, including Pre-Seed and Seed rounds, focusing on health technology solutions. This involvement highlights Sosv's commitment to supporting innovations that can impact the health and rehabilitation sectors, particularly through technology that may enhance physical therapy practices.



Physical Therapy and Rehabilitation Insights: Key Investors in the US


InvestorHeadquarterSizeFoundedDeals 2024
Y CombinatorSan Francisco, California, United States (USA)51-2002005802
Government of CanadaCanada, Kentucky, United States (USA)10001+1999137
MedTech InnovatorLos Angeles, California, United States (USA)11-50201385
StartUp HealthNew York, New York, United States (USA)11-5020110
OrbiMedNew York, New York, United States (USA)51-200198952
New Enterprise Associates (NEA)Menlo Park, California, United States (USA)51-200197757
Deep Tech Fund (an Alumni Ventures Fund)Manchester, New Hampshire, United States (USA)51-2002023258
Silicon Valley BankSanta Clara, California, United States (USA)5001-10000198331
Plug and Play Tech CenterSunnyvale, California, United States (USA)501-10002006253
Perceptive AdvisorsNew York, New York, United States (USA)11-50199945
GaingelsBurlington, Vermont, United States (USA)11-50201560
Polaris PartnersBoston, Massachusetts, United States (USA)11-50199619
General CatalystSan Francisco, California, United States (USA)51-2002000144
F-PrimeCambridge, Massachusetts, United States (USA)11-50194639
Frazier Healthcare PartnersSeattle, Washington, United States (USA)51-200199127
GV (Google Ventures)San Francisco Bay Area, California, United States (USA)51-200200974
SosvUnited States (USA)51-2001995170


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