The AI for healthcare industry in the U.S. merges artificial intelligence with healthcare solutions, focusing on improving patient outcomes and operational efficiency. Companies within this sector include tech startups, established healthcare firms, and research organizations. They offer innovations like diagnostic tools, predictive analytics, and telemedicine solutions. Currently, AI is more than just a buzzword; it's transforming how healthcare is delivered, enabling personalized medicine and data-driven decision-making. With ongoing advancements, experts predict a surge in healthcare AI investments, highlighting its essential role in future healthcare solutions, while generating exciting opportunities for both patients and providers.


The investors listed here comprise a mix of venture capital firms, each with a focused mission on enhancing the AI for healthcare sector. Headquartered primarily in California and New York, these firms vary in size from small teams to global powerhouses, and were founded from 1977 to 2015. In 2024, they collectively engaged in 13 unique investors, reflecting their commitment to innovation in healthcare technology. Some prominent names include New Enterprise Associates and Intel Capital, which have established influential roles through their investments and guidance of emerging companies.


Top 13 AI for Healthcare Investors in the US


1. Y Combinator

  • Website: ycombinator.com
  • Type: Venture Capital
  • Headquarters: San Francisco, California, United States (USA)
  • Founded year: 2005
  • Headcount: 51-200
  • Number of deals in 2024: 802
  • LinkedIn: y-combinator

Y Combinator is a prominent startup accelerator and venture capital firm based in San Francisco, California, founded in 2005. It provides funding and mentorship to early-stage technology companies through a structured program that helps entrepreneurs launch and grow their businesses. Y Combinator has successfully launched over 4,000 startups, establishing itself as a key player in the technology startup ecosystem. Among its notable investments in the healthcare sector, Y Combinator has backed Qventus, which raised $13 million in Series A funding in 2016 and focuses on using AI to enhance hospital operations. Additionally, they have invested in Bunkerhill Health, which raised funds in both seed and venture rounds, indicating their commitment to supporting innovative healthcare solutions. These transactions highlight Y Combinator's involvement in the AI for healthcare space, showcasing their role in fostering technological advancements in this industry.


2. Plug and Play Tech Center


Plug and Play Tech Center is an innovation hub and venture capital firm based in Sunnyvale, California, founded in 2006. They connect startups with corporations to foster growth and innovation, offering various programs including accelerator initiatives and investment opportunities. In 2024 alone, they made 253 investments, showcasing their active role in the venture capital landscape. Notably, they have invested in companies like Owkin, which raised $25 million in Series A funding in 2020 and focuses on AI applications in healthcare. Additionally, they have been involved with DataRobot, a machine-learning software company that, while not exclusively healthcare-focused, has applications in the sector. Their diverse portfolio and specific investments in AI-driven healthcare solutions position them as a significant player in the AI for healthcare investment space.


3. Deep Tech Fund (an Alumni Ventures Fund)

  • Website: av.vc
  • Type: Venture Capital
  • Headquarters: Manchester, New Hampshire, United States (USA)
  • Founded year: 2023
  • Headcount: 51-200
  • Number of deals in 2024: 258
  • LinkedIn: deep-tech-fund-av-focused-fund

The Deep Tech Fund, part of Alumni Ventures, is a venture capital firm based in Manchester, New Hampshire, founded in 2023. It provides accredited investors and institutions access to professionally-managed, diversified venture portfolios, leveraging a network of over 10,000 investors to connect them with high-quality investment opportunities. The fund has been involved in significant transactions in the AI for healthcare space, including PulseData, which raised $16.5 million for AI solutions targeting chronic kidney disease, and Sorcero, which secured $10 million for its AI-driven medical affairs and regulatory solutions. Additionally, the fund participated in funding rounds for Woebot Health, a therapy chatbot startup, and Luma Health, which focuses on patient access and communications, further demonstrating its commitment to investing in innovative healthcare solutions.


4. MedTech Innovator

  • Website: medtechinnovator.org
  • Type: Corporate
  • Headquarters: Los Angeles, California, United States (USA)
  • Founded year: 2013
  • Headcount: 11-50
  • Number of deals in 2024: 85
  • LinkedIn: medtech-innovator

MedTech Innovator is a not-for-profit organization based in Los Angeles, California, founded in 2013. It serves as the largest accelerator for medical technology companies, offering accelerator programs, mentorship, and competitions to support startups in the medical device, digital health, and diagnostics sectors. In recent years, MedTech Innovator has been involved in several transactions that highlight its focus on innovative healthcare solutions. For instance, it provided grants to Arterys and MedAware, both of which are engaged in AI-driven healthcare technologies. Additionally, it has supported companies like VinBrain and Tricog Health through non-equity assistance, further emphasizing its commitment to fostering innovation in the healthcare space, including AI applications.


5. New Enterprise Associates (NEA)

  • Website: nea.com
  • Type: Venture Capital
  • Headquarters: Menlo Park, California, United States (USA)
  • Founded year: 1977
  • Headcount: 51-200
  • Number of deals in 2024: 57
  • LinkedIn: new-enterprise-associates

New Enterprise Associates (NEA) is a prominent venture capital firm founded in 1977, based in Menlo Park, California. With a focus on technology and healthcare sectors, NEA specializes in investment management and advisory services for startups. The firm partners with entrepreneurs to provide not only funding but also strategic guidance, helping them navigate the complexities of building successful businesses. NEA has been particularly active in the healthcare space, exemplified by its substantial investments in Tempus, a leader in AI-driven precision medicine. Over several funding rounds from 2017 to 2020, NEA contributed to Tempus's growth, which raised over $600 million to enhance its operations and expand into new disease areas. This involvement underscores NEA's commitment to fostering innovation at the intersection of AI and healthcare, making it a key player in this investment landscape.


6. Sosv

  • Website: sosv.com
  • Type: Venture Capital
  • Headquarters: United States (USA)
  • Founded year: 1995
  • Headcount: 51-200
  • Number of deals in 2024: 170
  • LinkedIn: sosv

Sosv is a venture capital firm founded in 1995, based in the United States, that specializes in funding and supporting deep tech startups through its development programs. With a focus on sectors like health and climate technology, Sosv provides venture capital investment and resources to help startups grow and succeed. Notably, Sosv has participated in several funding rounds for Mendel.ai, a clinical AI platform that aims to enhance cancer patient care by matching them with the best diagnostic and treatment methods. Their investments in Mendel.ai include seed funding in 2017, a convertible note in 2016, and a Series A round in 2021, showcasing their ongoing support for innovative healthcare solutions that utilize AI technology.


7. OrbiMed

  • Website: orbimed.com
  • Type: Venture Capital
  • Headquarters: New York, New York, United States (USA)
  • Founded year: 1989
  • Headcount: 51-200
  • Number of deals in 2024: 52
  • LinkedIn: orbimed-advisors

OrbiMed is a prominent investment firm based in New York, specializing in healthcare investments. Founded in 1989, the firm manages approximately $17 billion in assets across various investment strategies, focusing on biopharmaceuticals, medical devices, and healthcare services. OrbiMed has been actively involved in significant funding rounds for companies at the intersection of healthcare and technology. For instance, they led a $100 million Series F funding round for Health Catalyst, a company that provides data analytics solutions aimed at transforming healthcare delivery. Additionally, OrbiMed has invested in Insilico Medicine, which raised $110 million in Series E funding, focusing on AI-driven drug discovery. These investments underscore OrbiMed's strategic interest in companies that utilize AI to enhance healthcare services and outcomes.


8. 500 Global

  • Website: 500.co
  • Type: Venture Capital
  • Headquarters: San Francisco, California, United States (USA)
  • Founded year: 2010
  • Headcount: 201-500
  • Number of deals in 2024: 98
  • LinkedIn: 500-startups

500 Global is a venture capital firm and startup accelerator based in San Francisco, California, founded in 2010. The firm specializes in investing in early-stage technology companies, providing not only funding but also mentorship and resources to help founders scale their businesses. In 2024 alone, 500 Global made 98 investments, showcasing their active engagement in the startup ecosystem. Among their notable transactions in the AI for healthcare sector are investments in Aesop Technology, a Taiwanese medical AI startup, and NIRAMAI Health Analytix, which focuses on health analytics. They also invested in Stethy, a healthcare-related startup, further emphasizing their commitment to the healthcare AI domain. While 500 Global invests across various industries, their involvement in these healthcare AI startups highlights their relevance in this specific investment category.


9. StartUp Health

  • Website: startuphealth.com
  • Type: Venture Capital
  • Headquarters: New York, New York, United States (USA)
  • Founded year: 2011
  • Headcount: 11-50
  • LinkedIn: startuphealth

StartUp Health is a not-for-profit organization based in New York, founded in 2011, that focuses on health innovation. They support health entrepreneurs and startups through their Health Moonshot Communities, providing essential resources, networking opportunities, and media content aimed at addressing significant health challenges. StartUp Health has been involved in various transactions, including investments in companies like Mediktor, which utilizes AI for symptom assessment, and Perceiv AI, which focuses on predictive analytics in healthcare. Other notable investments include Hindsait, Inc., Patientory, and Curatio, all of which contribute to the health technology landscape. Their offerings include newsletters, podcasts, and a journal that highlight progress in health technology and innovation, further emphasizing their commitment to advancing healthcare solutions.


10. Silicon Valley Bank

  • Website: svb.com
  • Type: Venture Capital
  • Headquarters: Santa Clara, California, United States (USA)
  • Founded year: 1983
  • Headcount: 5001-10000
  • Number of deals in 2024: 31
  • LinkedIn: silicon-valley-bank

Silicon Valley Bank (SVB) is a commercial bank founded in 1983, specializing in providing financial services to the innovation economy, particularly tech startups and venture capital firms. With a focus on business banking, global payments, and asset management, SVB helps clients navigate financial challenges and supports their growth. In the healthcare sector, SVB has participated in several notable transactions, including a $220 million Series E funding round for Komodo Health, a company that creates a 'healthcare map' using data analytics. They also participated in funding for ClosedLoop, which raised $11 million in Series A funding, and AiCure, which raised $24.5 million in Series C funding, focusing on AI-driven solutions for medication adherence. Additionally, SVB provided a $50 million capital infusion to Teladoc Health, the largest telemedicine company in the US, showcasing their commitment to advancing healthcare technology through innovative financial support.


11. General Catalyst


General Catalyst is a venture capital firm founded in 2000, based in San Francisco, California. The firm specializes in early-stage and growth investments across various industries, including technology and healthcare. They provide capital and strategic guidance to help startups scale their operations effectively. Notably, General Catalyst has made significant investments in the AI for healthcare sector, including Aidoc, which raised $66 million in a Series C funding round to enhance its AI-driven medical imaging solutions. Additionally, they have been a key investor in PathAI, participating in multiple funding rounds totaling $165 million in Series C, $60 million in Series B, and $11 million in Series A, all aimed at advancing AI applications in pathology. Their recent investment in Hippocratic AI, which raised $141 million in Series B, further emphasizes their focus on AI technologies in healthcare. Overall, General Catalyst's investment strategy reflects a strong commitment to fostering innovation in the healthcare industry through AI.


12. GV (Google Ventures)

  • Website: gv.com
  • Type: Venture Capital
  • Headquarters: San Francisco Bay Area, California, United States (USA)
  • Founded year: 2009
  • Headcount: 51-200
  • Number of deals in 2024: 74
  • LinkedIn: gv

GV (Google Ventures) is a venture capital firm based in the San Francisco Bay Area, founded in 2009. With over $10 billion in assets under management, GV focuses on providing funding and support to innovative technology startups across various sectors, including life sciences and artificial intelligence. Notably, GV has participated in several key transactions in the AI for healthcare domain, such as investing in Viz, which raised $100 million in Series D funding to enhance medical imaging through AI. Additionally, GV was involved in Ultromics' Series B funding round, which raised $33 million to accelerate the use of AI-enabled echocardiograms aimed at improving patient care. They also invested in Owkin, which raised $25 million in Series A funding to advance AI applications in healthcare. These investments highlight GV's active role in supporting AI-driven healthcare innovations.


13. Intel Capital

  • Website: intelcapital.com
  • Type: Venture Capital
  • Headquarters: Santa Clara, California, United States (USA)
  • Founded year: 1991
  • Headcount: 11-50
  • Number of deals in 2024: 23
  • LinkedIn: intelcapital

Intel Capital is a venture capital firm based in Santa Clara, California, founded in 1991. The firm specializes in investing in early-stage technology companies, with a focus on areas such as AI, cloud computing, and semiconductor technologies. Intel Capital provides funding, strategic support, and access to Intel's extensive resources to help startups scale and innovate within the tech ecosystem. Notably, Intel Capital has invested in DataRobot, a leading AI platform that has raised significant funding rounds, indicating their commitment to AI technologies. Additionally, they have invested in CareCloud, a provider of cloud-based practice management and EHR solutions, which highlights their engagement in the healthcare technology sector. These transactions demonstrate Intel Capital's active role in supporting innovations that leverage AI in healthcare contexts.



AI for Healthcare Insights: Key Investors in the US


InvestorHeadquarterSizeFoundedDeals 2024
Y CombinatorSan Francisco, California, United States (USA)51-2002005802
Plug and Play Tech CenterSunnyvale, California, United States (USA)501-10002006253
Deep Tech Fund (an Alumni Ventures Fund)Manchester, New Hampshire, United States (USA)51-2002023258
MedTech InnovatorLos Angeles, California, United States (USA)11-50201385
New Enterprise Associates (NEA)Menlo Park, California, United States (USA)51-200197757
SosvUnited States (USA)51-2001995170
OrbiMedNew York, New York, United States (USA)51-200198952
500 GlobalSan Francisco, California, United States (USA)201-500201098
StartUp HealthNew York, New York, United States (USA)11-5020110
Silicon Valley BankSanta Clara, California, United States (USA)5001-10000198331
General CatalystSan Francisco, California, United States (USA)51-2002000144
GV (Google Ventures)San Francisco Bay Area, California, United States (USA)51-200200974
Intel CapitalSanta Clara, California, United States (USA)11-50199123


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