Venture capital firms in Pennsylvania play a critical role in supporting innovative startups across various sectors such as technology, healthcare, and energy. They provide essential funding and mentorship, helping companies develop disruptive ideas into scalable products. This industry has evolved significantly, with a strong emphasis on early-stage investments that promise potential growth. Increasing collaboration with academic institutions and industry networks enhances access to cutting-edge research and development. As economic landscapes shift, many firms are also exploring sustainable and socially responsible investment opportunities, reflecting a growing trend towards ethical financing in the venture capital ecosystem.

This list features twenty venture capital firms based in Pennsylvania, varying in size, with some employing a dozen staff members while others boast teams of over 200. These firms are headquartered across major cities like Philadelphia and Pittsburgh and range in inception from 1996 to 2020. Their specializations include sectors such as healthcare technology, software development, and sports innovation, displaying a focus on emerging markets and technological advancements. Collectively, they have shaped the Pennsylvania startup environment through commitment and investment in early-stage enterprises.

Continue reading to discover Pennsylvania's top venture capital firms.

Top 20 Venture Capital Companies in Pennsylvania

1. Robin Hood Ventures

• Website: robinhoodventures.com
• Ownership type: Private
• Headquarters: Philadelphia, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 1999
• Headcount: 51-200
• LinkedIn: robin-hood-ventures

Robin Hood Ventures is an angel investment group based in Philadelphia, Pennsylvania, founded in 1999. The firm specializes in providing funding and mentorship to early-stage startups, primarily in the technology and healthcare sectors. With a team of experienced entrepreneurs and accredited investors, Robin Hood Ventures invests between $250,000 and $1 million in high-growth companies. Their approach goes beyond financial support; they offer guidance on business growth, access to follow-on investments, and valuable networking opportunities. The firm has invested in over 85 startups, demonstrating a strong commitment to fostering innovation and economic growth in the Mid-Atlantic region. Their portfolio includes companies across various industries, showcasing their adaptability and focus on scalable business models. Robin Hood Ventures also engages with the entrepreneurial community through events and resources, further solidifying their role in the startup ecosystem.

2. Dreamit Ventures

• Website: dreamit.com
• Ownership type: Private
• Headquarters: Philadelphia, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2008
• Headcount: 11-50
• LinkedIn: dreamit-ventures

Dreamit Ventures, founded in 2008 and based in Philadelphia, Pennsylvania, is a venture capital firm that specializes in investing in early-stage cybersecurity startups. With a team of 48 employees, Dreamit Ventures has built a reputation for its hands-on approach to investment. They typically invest between $500,000 and $1.5 million in pre-Series A companies that have shown early product-market fit through revenue or pilot programs. Dreamit Ventures not only provides capital but also offers strategic guidance and access to a robust network of over 70 cybersecurity partners. Their unique Customer Sprints and Investor Sprints facilitate meaningful introductions between startups and potential customers or investors, enhancing the growth potential of their portfolio companies. Since its inception, Dreamit has invested in more than 300 companies across various funds, demonstrating a strong track record in the cybersecurity sector.

3. Osage Venture Partners

• Website: osageventurepartners.com
• Ownership type: Family Owned
• Headquarters: Bala Cynwyd, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2005
• Headcount: 1-10
• LinkedIn: osage-partners

Osage Venture Partners, based in Bala Cynwyd, Pennsylvania, is a venture capital firm established in 2005. The firm specializes in investing in early-stage B2B software companies, with a particular emphasis on the future of work and education sectors. Osage Venture Partners aims to provide not just capital but also strategic support to entrepreneurs, helping them navigate the complexities of growth and development. Their investment strategy is centered around partnering with exceptional entrepreneurs who possess deep domain expertise and the potential for significant revenue growth. The firm has built a portfolio of over thirty companies, reflecting their commitment to fostering innovation and business technology advancement. They focus on post-revenue companies, typically with a revenue run rate between $500,000 and $3,000,000, and prefer to invest in Seed or Series A rounds. Osage Venture Partners is known for its collaborative approach, often leading or co-leading investments and actively participating in the governance of their portfolio companies.

4. SeventySix Capital

• Website: seventysixcapital.com
• Ownership type: Private
• Headquarters: King Of Prussia, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: November 2018
• Founded year: 1999
• Headcount: 1-10
• LinkedIn: seventysix-capital

SeventySix Capital, based in King of Prussia, Pennsylvania, is a venture capital firm established in 1999. The firm specializes in investing in innovative companies within the sports tech, gaming, and sports betting sectors. They provide not only funding but also strategic advisory services, helping entrepreneurs navigate the complexities of the sports industry. SeventySix Capital is known for its active involvement in the growth of its portfolio companies, offering expertise in business development, marketing, and operations. Their portfolio includes companies that are at the forefront of technological advancements in sports, such as data analytics, compliance, and digital media. The firm also engages with the entrepreneurial community through initiatives like the Athlete Venture Group, which allows professional athletes to invest in and collaborate with startups. This multifaceted approach underscores their commitment to fostering innovation in sports and entertainment.

5. Empactful Capital

• Website: empactfulcapital.com
• Ownership type: Private
• Headquarters: Doylestown, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2016
• Headcount: 1-10
• LinkedIn: empactfulcapital

Empactful Capital, founded in 2016 and based in Doylestown, Pennsylvania, is a venture capital firm dedicated to investing in healthcare technology. The firm partners with entrepreneurs to provide not just financial backing but also operational support aimed at enhancing patient care and engagement. Their investment strategy is rooted in a deep understanding of the healthcare sector, allowing them to assist startups in navigating challenges and achieving growth milestones. Empactful Capital's portfolio includes companies that focus on innovative solutions for whole-person care, addressing both physical and mental health needs. Their team boasts extensive experience in healthcare and entrepreneurship, which they leverage to foster meaningful relationships with founders. This holistic approach positions them as a valuable player in the healthcare investment landscape.

6. Oxygen Ventures

• Website: ov.partners
• Ownership type: Private
• Headquarters: Hummelstown, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2004
• Headcount: 11-50
• LinkedIn: oxygen-ventures

Oxygen Ventures, based in Hummelstown, Pennsylvania, is an advisory firm that specializes in growth capital and investment services. Founded in 2004, the firm has built a reputation for providing venture capital funding, investment advisory, and operational excellence to startups and private equity firms. Their mission is to help businesses accelerate growth and enhance value through tailored strategies and expert support. Oxygen Ventures works closely with technology startups, small and medium-sized businesses, and entrepreneurs, leveraging their experience and methodologies to create impactful growth strategies. They also offer a range of services including market research, operational excellence, and talent management, which are designed to elevate business performance. Their portfolio includes various companies across different sectors, showcasing their commitment to fostering innovation and supporting the growth of emerging businesses.

7. Osage University Partners (OUP)

• Website: oup.vc
• Ownership type: Private
• Headquarters: Bala Cynwyd, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2009
• Headcount: 11-50
• LinkedIn: osage-university-partners

Osage University Partners (OUP) is a venture capital firm based in Bala Cynwyd, Pennsylvania, founded in 2009. The firm specializes in investing in startups that emerge from university research, focusing on deep technology and scientific innovations. OUP collaborates closely with technology transfer offices at over 100 universities, providing capital, support, and connections to help these startups transition from research to market. With approximately $800 million under management, OUP has built a portfolio of more than 130 companies, achieving 33 successful IPOs. Their investment strategy spans all stages of company development, from seed to late-stage funding, and they are particularly active in sectors such as software, hardware, climate tech, therapeutics, medtech, diagnostics, and research tools. OUP's commitment to fostering innovation in academia and their extensive network within the university ecosystem make them a significant player in the venture capital industry.

8. KBJ Capital

• Website: kbjcapital.com
• Ownership type: Corporate
• Headquarters: Wilkes-Barre, Pennsylvania, United States (USA)
• Employee distribution: Thailand 67%, United States (USA) 33%
• Latest funding: April 2019
• Founded year: 2010
• Headcount: 1-10
• LinkedIn: kbj-capital

KBJ Capital, based in Wilkes-Barre, Pennsylvania, is an investment firm that specializes in supporting technology startups and entrepreneurs. Founded in 2010 by Kristopher B. Jones, a seasoned entrepreneur known for his success with Pepperjam, KBJ Capital aims to empower founders by providing funding, mentorship, and access to a broad network of industry connections. The firm has a portfolio that includes 20 companies, showcasing its commitment to nurturing early-stage ventures. Notably, KBJ Capital has helped its startups raise over $40 million from prominent venture capital firms in the past. However, the last reported funding activity was in April 2019, which may suggest a shift in focus or strategy. Despite this, the firm continues to emphasize its role in guiding entrepreneurs through the challenges of building and scaling their businesses.

9. Jota2 Group

• Website: jota2group.com
• Ownership type: Private
• Headquarters: Chester, Pennsylvania, United States (USA)
• Employee distribution: Spain 38%, Portugal 25%, United Arab Emirates 12%, Other 25%
• Founded year: 2013
• Headcount: 11-50
• LinkedIn: jota2-limited

Jota2 Group is an investment group based in Chester, Pennsylvania, established in 2013. The firm focuses on co-founding and investing in early-stage companies across various industries, with a strong emphasis on technology and innovation. Their portfolio includes companies in fintech, robotics, and other tech-driven sectors. Jota2 Group not only provides capital but also offers consulting services to help startups navigate marketing, sales, and strategic decisions. Their team consists of former founders and industry experts, which allows them to bring valuable insights and operational support to the companies they invest in. With a presence in over 22 countries and a commitment to responsible and sustainable investment practices, Jota2 Group aims to foster growth and innovation in the startups they partner with.

10. LLR Partners

• Website: llrpartners.com
• Ownership type: Private
• Headquarters: Philadelphia, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: Other (Debt), September 2021
• Founded year: 1999
• Headcount: 51-200
• LinkedIn: llr-partners

LLR Partners, founded in 1999 and based in Philadelphia, Pennsylvania, is a private equity firm that specializes in providing growth capital and strategic consulting services. With a focus on technology and healthcare, LLR Partners collaborates closely with business leaders to define and implement impactful growth initiatives. The firm has raised over $7 billion across seven funds, demonstrating its significant presence in the private equity space. LLR's investment strategy targets lower middle-market companies, typically investing between $25 million and $200 million in equity. Their portfolio spans various sectors, including education, FinTech, industrial technology, and software, showcasing their commitment to sectors with strong growth potential. LLR Partners emphasizes a partnership approach, leveraging their extensive network and resources to help portfolio companies accelerate growth and create long-term value.

11. Funema

• Website: funema.co
• Ownership type: Private
• Headquarters: King Of Prussia, Pennsylvania, United States (USA)
• Employee distribution: South Africa 68%, United States (USA) 16%, Nigeria 16%
• Founded year: 2017
• Headcount: 1-10
• LinkedIn: funema

Funema is a venture capital firm based in King of Prussia, Pennsylvania, founded in 2017. The firm is dedicated to building last-mile economies in emerging markets, particularly in Africa. Funema supports entrepreneurs by offering venture building services, training, and investment opportunities. Their mission is to empower underserved communities and transform challenges into sustainable business growth. Funema operates with a strong belief in the potential of innovative solutions to address economic disparities. They have engaged with various startups, focusing on sectors like inclusive finance and technology, and have trained numerous talents in venture capital and technology. Their portfolio includes companies that tackle significant challenges in their respective markets, aiming to create jobs and foster economic development.

12. BioAdvance

• Website: bioadvance.com
• Ownership type: Private
• Headquarters: Philadelphia, Pennsylvania, United States (USA)
• Employee distribution: Canada 50%, Portugal 25%, Argentina 25%
• Latest funding: Other (Grant), $14.8M, September 2022
• Founded year: 2003
• Headcount: 1-10
• LinkedIn: bioadvance

BioAdvance is a venture capital firm based in Philadelphia, Pennsylvania, founded in 2003. The firm focuses on early-stage investments in life sciences, specifically targeting companies that develop technologies to enhance human health. With a commitment to the mid-Atlantic region, BioAdvance has invested in over 100 companies, helping them grow and secure additional funding. Their portfolio includes a variety of health-related innovations, with 12 products having received FDA approval. BioAdvance operates as an evergreen fund, meaning it continues to grow and reinvest its capital. The firm has successfully facilitated 23 exits across various sectors, generating significant returns for its investors. Their investment strategy emphasizes capital efficiency and collaboration with entrepreneurs, ensuring that the companies they support can achieve critical milestones and attract further investment. In 2022, BioAdvance reported a funding amount of approximately $14.8 million, showcasing their ongoing activity in the venture capital market.

13. NewSpring

• Website: newspringcapital.com
• Ownership type: Private Equity
• Headquarters: Radnor, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 90%, Portugal 10%
• Latest funding: $2.8M, May 2024
• Founded year: 1999
• Headcount: 51-200
• LinkedIn: newspring-capital

NewSpring Capital, founded in 1999 and based in Radnor, Pennsylvania, is a private equity firm that specializes in growth capital for lower-middle market companies. With a team of experienced operators and investors, NewSpring focuses on building strong partnerships with management teams to help businesses achieve their growth objectives. They operate across several sectors, including technology and healthcare, and have developed a reputation for providing tailored investment solutions. As of May 2024, NewSpring has raised approximately $3.5 billion in assets under management and has made over 250 investments. Their commitment to the entrepreneurial spirit is reflected in their core values, which emphasize integrity, relationship-building, and a drive for excellence. NewSpring's recent funding activities further highlight their active role in the investment community, making them a notable entity in the venture capital sector.

14. Boathouse Capital

• Website: boathousecapital.com
• Ownership type: Family Owned
• Headquarters: Wayne, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2008
• Headcount: 11-50
• LinkedIn: boathouse-capital

Boathouse Capital, founded in 2008 and based in Wayne, Pennsylvania, is a private equity firm that focuses on providing flexible capital solutions tailored for growth and later-stage businesses in the lower middle market. The firm is dedicated to creating customized capital structures that support established companies across various sectors, including technology and healthcare. With a team that boasts over 100 years of combined experience and more than $1.5 billion invested, Boathouse Capital has completed over 100 transactions. Their clients primarily include financial sponsors and founder-led businesses seeking tailored investment strategies. The firm emphasizes value creation and aims to build scale in companies that are well-positioned for accelerated growth, making them a notable player in the investment community.

15. Semcap

• Website: semcap.com
• Ownership type: Private
• Headquarters: Wayne, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 87%, Canada 13%
• Founded year: 2020
• Headcount: 11-50
• LinkedIn: semcapholding

Semcap is an investment firm based in Wayne, Pennsylvania, founded in 2020. The firm specializes in growth impact investments across three primary sectors: healthcare, education, and food & nutrition. Semcap partners with entrepreneurs to provide not only capital but also strategic support, enabling businesses to scale and innovate effectively. The firm is particularly focused on transformative trends that are reshaping these industries, driven by technological advancements and changing consumer values. Semcap's founders, Buck Buckley and Cyrus Vandrevala, bring decades of experience in technology investments and entrepreneurship, which informs their investment strategy. They aim to generate above-market returns while ensuring that their investments lead to measurable positive outcomes for society. Semcap has not reported any funding rounds to date, indicating they may still be in the early stages of building their investment portfolio.

16. EnerTech Capital

• Website: enertechcapital.com
• Ownership type: Private
• Headquarters: Ambler, Pennsylvania, United States (USA)
• Employee distribution: Canada 58%, United States (USA) 42%
• Latest funding: $10.0M, May 2024
• Founded year: 1996
• Headcount: 11-50
• LinkedIn: enertech-capital

EnerTech Capital, based in Ambler, Pennsylvania, is a venture capital firm that specializes in energy technology investments. Founded in 1996, the firm has a history of collaborating with innovators to drive advancements in the energy sector. EnerTech focuses on three primary areas: mobility, Industry 4.0, and connected customer solutions. Over its 25 years of operation, EnerTech has made 73 investments and managed over $500 million in limited partner capital commitments. The firm actively engages with its portfolio companies, providing not just financial support but also strategic insights to help them navigate the complexities of the energy market. Recently, EnerTech secured $10 million in funding in May 2024, further demonstrating its active role in the venture capital landscape. Their approach emphasizes collaboration with corporate partners and stakeholders, enhancing their ability to identify and capitalize on emerging opportunities in energy innovation.

17. Hypothesis

• Website: hypothesis.studio
• Ownership type: Private
• Headquarters: Willow Grove, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2020
• Headcount: 1-10
• LinkedIn: hypothesisvc

Hypothesis is a startup studio and seed fund based in Willow Grove, Pennsylvania, founded in 2020. The company specializes in building and funding early-stage companies, offering initial capital along with comprehensive support in product design, recruiting, and marketing. Hypothesis operates with a belief that great companies can emerge from anywhere, not just traditional tech hubs. They emphasize a hands-on approach, working closely with founders to accelerate their ventures. Their portfolio includes a variety of innovative companies across sectors such as healthcare, data integration, and sustainability, showcasing their commitment to fostering impactful solutions. Hypothesis has not reported any external funding to date, but they have successfully helped their portfolio companies raise capital from top firms in the industry.

18. LifeX

• Website: lifexglobal.com
• Ownership type: Private
• Headquarters: Pittsburgh, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Latest funding: Other (Grant), $2.0M, November 2023
• Founded year: 2017
• Headcount: 1-10
• LinkedIn: lifexlabs

LifeX is a life sciences capital growth company based in Pittsburgh, Pennsylvania, founded in 2017. The firm specializes in supporting early-stage startups within the life sciences sector, providing essential resources and funding solutions to help entrepreneurs bring their innovations to market. LifeX's focus spans various areas, including pharmaceuticals, biotechnology, medical devices, diagnostics, and digital health technologies. They operate a commercialization program designed to assist startups in achieving key milestones, and they also run an accelerator program that offers immersive support for ventures in digital health and therapeutics. Recently, LifeX secured a $2 million grant in November 2023, further enhancing their capacity to support life science companies in their growth journey. Their collaborative approach, which includes partnerships with the University of Pittsburgh and other local entities, aims to cultivate a robust entrepreneurial ecosystem in southwestern Pennsylvania.

19. MissionOG

• Website: missionog.com
• Ownership type: Private
• Headquarters: Philadelphia, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 90%, United Kingdom (UK) 10%
• Latest funding: $93.0M, December 2019
• Founded year: 2012
• Headcount: 1-10
• LinkedIn: missionog

MissionOG is a Philadelphia-based investment firm established in 2012, specializing in high-growth B2B companies within the fintech, data, and software sectors. The firm prides itself on its operational background, which allows it to offer valuable insights and support to its portfolio companies. MissionOG seeks to invest between $5 million and $10 million, with the potential for follow-on capital as needed. Their investment philosophy is centered around partnering with companies that demonstrate a strong market presence and a commitment to customer success. Noteworthy portfolio companies include those that have gone through significant transitions, such as acquisitions and public offerings, showcasing MissionOG's ability to identify and nurture promising ventures. The firm has also raised substantial funding, with a reported last funding amount of $93 million in December 2019, indicating its active engagement in the investment community.

20. Mountain State Capital

• Website: mountainstatecapital.com
• Ownership type: Private
• Headquarters: Pittsburgh, Pennsylvania, United States (USA)
• Employee distribution: United States (USA) 100%
• Founded year: 2018
• Headcount: 1-10
• LinkedIn: mountain-state-capital

Mountain State Capital, founded in 2018 and based in Pittsburgh, Pennsylvania, is an investment firm that specializes in early-stage investments primarily in the technology and life sciences sectors. The firm aims to support businesses that have demonstrated product-market fit and are poised for growth. Their investment strategy typically involves participating in seed rounds, where they invest between $200,000 and $500,000, often as part of larger funding efforts. Mountain State Capital focuses on companies within the greater Appalachian region, including areas of West Virginia, Pennsylvania, Ohio, Kentucky, and beyond. The firm is led by experienced professionals with backgrounds in technology and investment, enhancing their ability to provide both capital and strategic guidance to their portfolio companies. They actively engage with their investments, ensuring a hands-on approach to fostering growth and success.

Venture Capital Insights: Key Companies in Pennsylvania

Company	Headquarter	Size	Founded	Ownership
Robin Hood Ventures	Philadelphia, Pennsylvania, United States (USA)	51-200	1999	Private
Dreamit Ventures	Philadelphia, Pennsylvania, United States (USA)	11-50	2008	Private
Osage Venture Partners	Bala Cynwyd, Pennsylvania, United States (USA)	1-10	2005	Family Owned
SeventySix Capital	King Of Prussia, Pennsylvania, United States (USA)	1-10	1999	Private
Empactful Capital	Doylestown, Pennsylvania, United States (USA)	1-10	2016	Private
Oxygen Ventures	Hummelstown, Pennsylvania, United States (USA)	11-50	2004	Private
Osage University Partners (OUP)	Bala Cynwyd, Pennsylvania, United States (USA)	11-50	2009	Private
KBJ Capital	Wilkes-Barre, Pennsylvania, United States (USA)	1-10	2010	Corporate
Jota2 Group	Chester, Pennsylvania, United States (USA)	11-50	2013	Private
LLR Partners	Philadelphia, Pennsylvania, United States (USA)	51-200	1999	Private
Funema	King Of Prussia, Pennsylvania, United States (USA)	1-10	2017	Private
BioAdvance	Philadelphia, Pennsylvania, United States (USA)	1-10	2003	Private
NewSpring	Radnor, Pennsylvania, United States (USA)	51-200	1999	Private Equity
Boathouse Capital	Wayne, Pennsylvania, United States (USA)	11-50	2008	Family Owned
Semcap	Wayne, Pennsylvania, United States (USA)	11-50	2020	Private
EnerTech Capital	Ambler, Pennsylvania, United States (USA)	11-50	1996	Private
Hypothesis	Willow Grove, Pennsylvania, United States (USA)	1-10	2020	Private
LifeX	Pittsburgh, Pennsylvania, United States (USA)	1-10	2017	Private
MissionOG	Philadelphia, Pennsylvania, United States (USA)	1-10	2012	Private
Mountain State Capital	Pittsburgh, Pennsylvania, United States (USA)	1-10	2018	Private

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