The surgical device industry in the US is crucial for advancing healthcare. It comprises companies that design, manufacture, and sell tools and equipment used in surgeries, ranging from minimally invasive instruments to sophisticated robotic systems. With continuous innovation driven by technology, the sector focuses on improving surgical outcomes and patient safety. Manufacturers play a key role in developing products like surgical staplers, endoscopes, and prosthetics. As the demand for precision and personalized medicine grows, the industry is increasingly embracing AI and robotics, steering towards a future with more efficient and effective surgical methods.


This compilation showcases a mix of venture capital firms and organizations investing in the surgical device sector. The listed investors, based in key US locations like San Francisco and New York, vary in size from as few as 11 employees to over 10,000. Founded between 1946 and 2023, these investors actively engaged in multiple deals in 2024, highlighting their commitment to supporting innovative startups tackling surgical challenges. The spectrum of funding interests indicates a robust environment fostering technological advancement in surgical procedures.


Top 13 Surgical Device Investors in the US


1. MedTech Innovator

  • Website: medtechinnovator.org
  • Type: Corporate
  • Headquarters: Los Angeles, California, United States (USA)
  • Founded year: 2013
  • Headcount: 11-50
  • Number of deals in 2024: 85
  • LinkedIn: medtech-innovator

MedTech Innovator is a not-for-profit organization based in Los Angeles, California, founded in 2013. It serves as the largest accelerator for medical technology companies, offering accelerator programs, mentorship, and competitions to support startups in the medical device, digital health, and diagnostics sectors. Notably, MedTech Innovator has been involved in several transactions relevant to the surgical device industry, including grants to Surgisense Corporation, AMT Surgical, and Augmedics, which focus on innovative surgical technologies. Additionally, it has provided non-equity assistance to companies like New View Surgical and Lazurite, further emphasizing its role in nurturing surgical device innovation. Through these efforts, MedTech Innovator plays a significant role in helping surgical device startups grow and innovate within the healthcare space.


2. OrbiMed

  • Website: orbimed.com
  • Type: Venture Capital
  • Headquarters: New York, New York, United States (USA)
  • Founded year: 1989
  • Headcount: 51-200
  • Number of deals in 2024: 52
  • LinkedIn: orbimed-advisors

OrbiMed is a prominent investment firm based in New York, specializing in healthcare investments since its founding in 1989. With approximately $17 billion in assets under management, OrbiMed focuses on biopharmaceuticals, medical devices, and healthcare services. Notably, OrbiMed has participated in significant funding rounds for surgical device companies, including SI-BONE, which raised multiple rounds of funding totaling over $60 million to support its expansion and clinical studies. Additionally, OrbiMed invested in Cerapedics, which raised $19 million in Series C funding, further demonstrating its commitment to the surgical device sector. OrbiMed's diverse portfolio and strategic investments in innovative healthcare companies position it as a key player in driving advancements in surgical devices.


3. Y Combinator

  • Website: ycombinator.com
  • Type: Venture Capital
  • Headquarters: San Francisco, California, United States (USA)
  • Founded year: 2005
  • Headcount: 51-200
  • Number of deals in 2024: 802
  • LinkedIn: y-combinator

Y Combinator is a prominent startup accelerator and venture capital firm based in San Francisco, California, founded in 2005. It provides funding and mentorship to early-stage technology companies through a structured program that includes resources like the Startup School and co-founder matching services. Y Combinator has successfully launched over 4,000 startups, making it a key player in the technology startup ecosystem. Notably, Y Combinator has invested in several surgical device companies, including Revolve Surgical, which raised $125,000 in a Pre-Seed round in August 2021, and Illuminant Surgical, which secured $500,000 in a Pre-Seed round in August 2022. Additionally, they invested in Allotrope Medical during its Seed round in August 2018 and Andromeda Surgical in April 2023. These transactions highlight Y Combinator's involvement in the surgical device industry, showcasing their commitment to supporting innovation in this field.


4. New Enterprise Associates (NEA)

  • Website: nea.com
  • Type: Venture Capital
  • Headquarters: Menlo Park, California, United States (USA)
  • Founded year: 1977
  • Headcount: 51-200
  • Number of deals in 2024: 57
  • LinkedIn: new-enterprise-associates

New Enterprise Associates (NEA) is a prominent venture capital firm based in Menlo Park, California, founded in 1977. NEA specializes in investment management and advisory services for startups, particularly in the technology and healthcare sectors. The firm partners with entrepreneurs to provide funding and strategic guidance, helping them navigate the challenges of building successful businesses. NEA operates through a collaborative approach, emphasizing long-term relationships with founders. Notably, NEA has been involved in significant transactions within the surgical device industry, including multiple funding rounds for Cartiva, which raised funds to support its MOTION study and FDA application, and Spine Wave, which received substantial financing to advance its commercial operations and clinical trials for its NuCore Injectable Nucleus product. These investments highlight NEA's active role in the surgical device market, reinforcing their relevance in this category.


5. Sosv

  • Website: sosv.com
  • Type: Venture Capital
  • Headquarters: United States (USA)
  • Founded year: 1995
  • Headcount: 51-200
  • Number of deals in 2024: 170
  • LinkedIn: sosv

SOSV is a venture capital firm founded in 1995, specializing in funding and supporting deep tech startups through its development programs. With a global reach, SOSV connects innovative companies with investors, providing venture capital investment and resources to help startups grow in various sectors, including health and climate technology. Notably, SOSV has invested in Ostoform, a Dublin-based medical devices startup, which raised funds in multiple rounds, including a Series A round in 2018 and subsequent funding in 2021 and 2025. Ostoform focuses on developing a stoma seal, and SOSV's involvement in these funding rounds highlights their commitment to advancing surgical device innovations. Additionally, SOSV's investment in CroíValve, which raised significant funds in 2024, further emphasizes their engagement in the health technology space, including surgical devices.


6. Perceptive Advisors


Perceptive Advisors is a New York-based venture capital firm founded in 1999, specializing in the life sciences sector. The firm provides capital solutions and investment management services to both private and public healthcare companies, with a strong emphasis on biotechnology, pharmaceuticals, and medical devices. Notably, Perceptive Advisors has participated in significant transactions within the surgical device space, including a $37.5 million investment in Apyx Medical, which focuses on innovative surgical technologies, and involvement in multiple funding rounds for PROCEPT BioRobotics, a company known for its AquaBeam Robotic System and Aquablation therapy for treating benign prostate hyperplasia. These investments highlight Perceptive Advisors' commitment to supporting innovation and growth in the surgical device industry.


7. Deep Tech Fund (an Alumni Ventures Fund)

  • Website: av.vc
  • Type: Venture Capital
  • Headquarters: Manchester, New Hampshire, United States (USA)
  • Founded year: 2023
  • Headcount: 51-200
  • Number of deals in 2024: 258
  • LinkedIn: deep-tech-fund-av-focused-fund

Deep Tech Fund (an Alumni Ventures Fund) is a venture capital firm based in Manchester, New Hampshire, founded in 2023. It provides accredited investors and institutions with access to professionally-managed, diversified venture portfolios. With a network of over 10,000 investors, the firm focuses on connecting them with high-quality investment opportunities in the startup ecosystem. The fund has been involved in significant transactions in the surgical device context, including a $15 million Series B investment in Activ Surgical in March 2022 and a $7.2 million Series A investment in Innoblative Designs in May 2017. These investments highlight the fund's engagement in the surgical device industry, particularly in innovative technologies that enhance surgical procedures.


8. Silicon Valley Bank

  • Website: svb.com
  • Type: Venture Capital
  • Headquarters: Santa Clara, California, United States (USA)
  • Founded year: 1983
  • Headcount: 5001-10000
  • Number of deals in 2024: 31
  • LinkedIn: silicon-valley-bank

Silicon Valley Bank is a commercial bank founded in 1983, located in Santa Clara, California, that specializes in providing financial services to the innovation economy, particularly tech startups and venture capital firms. They offer a range of products including business banking, global payments, and asset management, helping clients navigate financial challenges and support their growth. Notably, Silicon Valley Bank has been involved in several key transactions within the surgical device industry, including providing post-IPO debt financing to Cardiovascular Systems, Asensus Surgical, and Sientra, as well as debt financing to Cartiva and Cayenne Medical. These investments highlight their engagement with companies that are pivotal in the surgical device market, reinforcing their role as a significant player in this sector.


9. Plug and Play Tech Center


Plug and Play Tech Center is an innovation hub and venture capital firm based in Sunnyvale, California, founded in 2006. They connect startups with corporations to foster growth and innovation, offering various programs including accelerator initiatives and investment opportunities primarily in the technology sector. In recent years, they have made significant investments in the surgical device industry, notably in Caresyntax, which raised $80 million in Series C funding in August 2024, and previously raised $45.6 million in Series B funding in December 2019. Additionally, they invested in MediView XR, a startup focused on medical devices, which raised $4.5 million in seed funding in October 2019. These transactions highlight their active role in supporting surgical device innovation and development.


10. Oxford Finance LLC

  • Website: oxfordfinance.com
  • Type: Corporate
  • Headquarters: Alexandria, Virginia, United States (USA)
  • Founded year: 2002
  • Headcount: 51-200
  • Number of deals in 2024: 2
  • LinkedIn: oxford-finance-llc

Oxford Finance LLC is a financial services company founded in 2002, based in Alexandria, Virginia. The firm specializes in providing flexible lending solutions to middle-market companies, particularly in the life sciences and healthcare sectors. They offer a variety of financial products, including enterprise lending, leveraged lending, and real estate financing, aimed at helping businesses secure the necessary capital for growth and innovation. Notably, Oxford Finance has been involved in significant transactions within the surgical device industry, such as providing $50 million in debt financing to ConforMIS, a company focused on orthopedic implants, and $250 million in post-IPO debt to Silk Road Medical, which develops innovative surgical devices. These transactions highlight their active role in supporting the surgical device sector, making them a relevant investor in this field.


11. Polaris Partners

  • Website: polarispartners.com
  • Type: Venture Capital
  • Headquarters: Boston, Massachusetts, United States (USA)
  • Founded year: 1996
  • Headcount: 11-50
  • Number of deals in 2024: 19
  • LinkedIn: polaris-partners

Polaris Partners is a venture capital firm based in Boston, Massachusetts, founded in 1996. The firm specializes in healthcare and biotechnology investments, partnering with entrepreneurs to provide funding and strategic guidance to help them innovate and grow their businesses. Polaris has a diverse portfolio that includes companies focused on transformative healthcare solutions. Notably, Polaris has been involved in several funding rounds for BridgePoint Medical, a company dedicated to developing advanced surgical devices for vascular access, raising significant amounts across multiple rounds from 2006 to 2010. Additionally, they invested in Aspect Medical Systems, which also aligns with their focus on healthcare technology. This track record highlights Polaris Partners' commitment to supporting early-stage companies in the surgical device space.


12. GV (Google Ventures)

  • Website: gv.com
  • Type: Venture Capital
  • Headquarters: San Francisco Bay Area, California, United States (USA)
  • Founded year: 2009
  • Headcount: 51-200
  • Number of deals in 2024: 74
  • LinkedIn: gv

GV (Google Ventures) is a venture capital firm founded in 2009, based in the San Francisco Bay Area, with over $10 billion in assets under management. The firm provides funding and support to innovative technology startups across various sectors, including life sciences and artificial intelligence. Notably, GV has participated in significant funding rounds for companies in the surgical device space, such as Hyperfine Research, which raised $90 million to scale its portable MR imaging platform, and Element Science, which raised $145.6 million for its Jewel Patch Wearable Cardioverter Defibrillator. These transactions highlight GV's involvement in advancing medical technology and surgical devices, showcasing their commitment to supporting innovations that improve healthcare outcomes.


13. Medtronic

  • Website: medtronic.com
  • Type: Corporate
  • Headquarters: Minneapolis, Minnesota, United States (USA)
  • Founded year: 1949
  • Headcount: 10001+
  • Number of deals in 2024: 2
  • LinkedIn: medtronic

Medtronic plc is a prominent medical device company founded in 1949, headquartered in Minneapolis, Minnesota. The company specializes in developing and manufacturing healthcare technologies and therapies aimed at improving health outcomes for patients globally. Medtronic has made significant investments in the surgical device industry, including the acquisition of Physio-Control in 1998 for $538 million, which expanded their portfolio in emergency medical services. More recently, in 2020, Medtronic announced its plan to acquire Medicrea for approximately $160 million, enhancing its capabilities in spinal surgery through AI and robotic technologies. Additionally, Medtronic's acquisition of Mazor Robotics for $1.7 billion in 2018 further solidified its position in the surgical robotics market. These strategic investments highlight Medtronic's focus on innovative surgical solutions and its active role in the surgical device sector.



Surgical Device Insights: Key Investors in the US


InvestorHeadquarterSizeFoundedDeals 2024
MedTech InnovatorLos Angeles, California, United States (USA)11-50201385
OrbiMedNew York, New York, United States (USA)51-200198952
Y CombinatorSan Francisco, California, United States (USA)51-2002005802
New Enterprise Associates (NEA)Menlo Park, California, United States (USA)51-200197757
SosvUnited States (USA)51-2001995170
Perceptive AdvisorsNew York, New York, United States (USA)11-50199945
Deep Tech Fund (an Alumni Ventures Fund)Manchester, New Hampshire, United States (USA)51-2002023258
Silicon Valley BankSanta Clara, California, United States (USA)5001-10000198331
Plug and Play Tech CenterSunnyvale, California, United States (USA)501-10002006253
Oxford Finance LLCAlexandria, Virginia, United States (USA)51-20020022
Polaris PartnersBoston, Massachusetts, United States (USA)11-50199619
GV (Google Ventures)San Francisco Bay Area, California, United States (USA)51-200200974
MedtronicMinneapolis, Minnesota, United States (USA)10001+19492


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