The biomedical engineering industry in the US combines medical science with engineering principles to develop innovative healthcare solutions. Companies in this sector create medical devices, imaging systems, and therapeutic technologies that enhance patient care. The industry is experiencing rapid growth, driven by advances in technology, increasing healthcare demands, and a rising focus on personalized medicine. Collaborations between academia and private enterprises are on the rise, fostering groundbreaking research and development. With a surge in investment and regulatory support, the future of biomedical engineering looks promising, paving the way for transformative healthcare advancements.


This list highlights key investors in the US biomedical engineering sector, showcasing a mix of venture capital firms and corporate innovation hubs. Located across cities like New York, San Francisco, and Boston, these investors vary in size and expertise. Many were founded in the 1990s and early 2000s, reflecting an established presence in the industry. In 2024, they collectively participated in over 1000 investments, signaling strong demand for innovative healthcare solutions. This diverse group, ranging from early-stage funding sources to established capital firms, reflects the robust investment landscape in biomedical engineering.


Top 13 Biomedical Engineering Investors in the US


1. MedTech Innovator

  • Website: medtechinnovator.org
  • Type: Corporate
  • Headquarters: Los Angeles, California, United States (USA)
  • Founded year: 2013
  • Headcount: 11-50
  • Number of deals in 2024: 85
  • LinkedIn: medtech-innovator

MedTech Innovator is a not-for-profit organization based in Los Angeles, California, founded in 2013. It serves as the largest accelerator for medical technology companies, offering accelerator programs, mentorship, and competitions to support startups in the medical device, digital health, and diagnostics sectors. In 2024 alone, MedTech Innovator has been involved in 85 investments, providing crucial support to emerging companies in the biomedical engineering landscape. Notable transactions include non-equity assistance to Lattice Medical and Arsenal Medical, as well as grants to Cognition Medical and Fibralign Corporation. These activities highlight MedTech Innovator's commitment to fostering innovation and growth in the healthcare space, particularly within the biomedical engineering domain.


2. Y Combinator

  • Website: ycombinator.com
  • Type: Venture Capital
  • Headquarters: San Francisco, California, United States (USA)
  • Founded year: 2005
  • Headcount: 51-200
  • Number of deals in 2024: 802
  • LinkedIn: y-combinator

Y Combinator is a prominent startup accelerator and venture capital firm based in San Francisco, California, founded in 2005. It provides funding and mentorship to early-stage technology companies through a structured program that includes resources like the Startup School and co-founder matching services. Y Combinator has successfully launched over 4,000 startups, making it a key player in the technology startup ecosystem. Among its diverse portfolio, Y Combinator has made significant investments in the biomedical engineering sector, including Rejuvenation Technologies, which raised $10.6M in a seed financing round to advance its programs for fibrotic diseases and immune system research. Additionally, they have invested in Trestle Biotherapeutics and Illuminant Surgical, further demonstrating their engagement in the biomedical field. These transactions highlight Y Combinator's role in supporting innovative solutions within biomedical engineering.


3. OrbiMed

  • Website: orbimed.com
  • Type: Venture Capital
  • Headquarters: New York, New York, United States (USA)
  • Founded year: 1989
  • Headcount: 51-200
  • Number of deals in 2024: 52
  • LinkedIn: orbimed-advisors

OrbiMed is an investment firm based in New York, specializing in healthcare investments since its founding in 1989. With approximately $17 billion in assets under management, OrbiMed focuses on companies engaged in biopharmaceuticals, medical devices, and healthcare services. The firm has made significant investments in the biomedical engineering sector, including a $1.1 billion business combination with Humacyte, a company known for its innovative human acellular vessels, and participation in funding rounds for SuperDimension, which specializes in advanced medical imaging technologies. These transactions highlight OrbiMed's active role in driving innovation within the biomedical engineering landscape, catering to both medical institutions and investment funds seeking to enhance healthcare solutions.


4. Sosv

  • Website: sosv.com
  • Type: Venture Capital
  • Headquarters: United States (USA)
  • Founded year: 1995
  • Headcount: 51-200
  • Number of deals in 2024: 170
  • LinkedIn: sosv

Sosv is a venture capital firm founded in 1995, specializing in funding and supporting deep tech startups through its development programs. With a global reach, Sosv connects innovative companies with investors, providing not only venture capital investment but also resources to help startups grow and succeed. In 2024, Sosv has made significant investments, including in BioLattice, which raised funds in multiple seed rounds, and Pregenerate, which has also secured funding through seed rounds and convertible notes. These transactions highlight Sosv's commitment to advancing health technology and its relevance in the biomedical engineering sector.


5. Perceptive Advisors


Perceptive Advisors is a New York-based investment firm founded in 1999, specializing in the life sciences sector. The firm provides capital solutions and investment management services to both private and public healthcare companies, with a strong focus on biotechnology, pharmaceuticals, and medical devices. Notably, Perceptive Advisors has participated in several significant transactions relevant to biomedical engineering, including a $110 million Series D investment in Orchestra BioMed in January 2022 and a $34 million Series B investment in the same company in March 2019. Additionally, they were involved in a $150 million private equity round for InSightec in June 2024, as well as a credit facility arrangement that provided $100 million in financing to InSightec in September 2022. These transactions highlight their commitment to supporting innovation and growth in the healthcare and biomedical engineering sectors.


6. New Enterprise Associates (NEA)

  • Website: nea.com
  • Type: Venture Capital
  • Headquarters: Menlo Park, California, United States (USA)
  • Founded year: 1977
  • Headcount: 51-200
  • Number of deals in 2024: 57
  • LinkedIn: new-enterprise-associates

New Enterprise Associates (NEA) is a prominent venture capital firm based in Menlo Park, California, founded in 1977. The firm specializes in investment management and advisory services for startups, particularly in the technology and healthcare sectors. NEA partners with entrepreneurs to provide funding and strategic guidance, helping them navigate the challenges of building successful businesses. Notably, NEA has been involved in significant transactions within the biomedical engineering field, including investments in Cartiva, which raised multiple funding rounds to support its innovative orthopedic solutions, and Spine Wave, which focuses on spinal technologies. These investments highlight NEA's commitment to advancing healthcare through innovative biomedical engineering solutions.


7. Deep Tech Fund (an Alumni Ventures Fund)

  • Website: av.vc
  • Type: Venture Capital
  • Headquarters: Manchester, New Hampshire, United States (USA)
  • Founded year: 2023
  • Headcount: 51-200
  • Number of deals in 2024: 258
  • LinkedIn: deep-tech-fund-av-focused-fund

The Deep Tech Fund (an Alumni Ventures Fund) is a venture capital firm based in Manchester, New Hampshire, founded in 2023. It provides accredited investors and institutions with access to professionally-managed, diversified venture portfolios, leveraging a network of over 10,000 investors to connect them with high-quality investment opportunities in the startup ecosystem. The fund has been actively involved in the biomedical engineering sector, participating in notable transactions such as the $41 million Series B funding for Precision Neuroscience, which focuses on advancing brain health technologies, and the $8 million Seed funding for Axoft, a neurotechnology company developing neural implants. Additionally, the fund has engaged with Bionaut Labs and Harbor MedTech, further solidifying its commitment to investing in innovative biomedical engineering solutions.


8. ARCH Venture Partners

  • Website: archventure.com
  • Type: Venture Capital
  • Headquarters: Chicago, Illinois, United States (USA)
  • Founded year: 1986
  • Headcount: 11-50
  • Number of deals in 2024: 32
  • LinkedIn: arch-venture-partners

ARCH Venture Partners is a venture capital firm founded in 1986, based in Chicago, Illinois, specializing in biotechnology investments. The firm provides funding and strategic support to innovative companies in the life sciences sector, helping them navigate the complexities of bringing new technologies to market. ARCH has been actively involved in several notable transactions in the biomedical engineering field, including investments in Synchron, a company focused on advanced neural interface technology, and Quanterix, which develops ultrasensitive diagnostic tools for precision medicine. Their investments in these companies highlight their commitment to supporting groundbreaking medical solutions and technologies, making them a key player in the biomedical engineering landscape.


9. Silicon Valley Bank

  • Website: svb.com
  • Type: Venture Capital
  • Headquarters: Santa Clara, California, United States (USA)
  • Founded year: 1983
  • Headcount: 5001-10000
  • Number of deals in 2024: 31
  • LinkedIn: silicon-valley-bank

Silicon Valley Bank is a commercial bank founded in 1983, located in Santa Clara, California, specializing in providing financial services to the innovation economy, particularly tech startups and venture capital firms. They offer a range of products including business banking, global payments, and asset management, helping clients navigate financial challenges and support their growth. Notably, Silicon Valley Bank has been involved in significant debt financing transactions within the biomedical engineering sector, such as a $50 million raise for Humacyte in 2021, a $1.5 million raise for Cartiva in 2014, and multiple rounds of financing for CardioFocus, totaling $16 million between 2011 and 2013. Additionally, they supported Cardiovascular Systems with $29 million in post-IPO debt in 2010. These transactions highlight their active role in funding innovative biomedical companies, reinforcing their relevance in this industry.


10. Casdin Capital, LLC

  • Website: casdincapital.com
  • Type: Venture Capital
  • Headquarters: New York, New York, United States (USA)
  • Founded year: 2012
  • Headcount: 11-50
  • Number of deals in 2024: 9
  • LinkedIn: casdin-capital-llc

Casdin Capital, LLC is a New York-based venture capital firm founded in 2012, specializing in the life sciences sector. The firm focuses on investing in healthcare, biotechnology, synthetic biology, and technology, providing funding and strategic partnerships to innovative companies. Notable transactions include a $27.5 million investment in Xcell Biosciences, which is involved in cell therapy, and a $106 million investment in Tenaya Therapeutics, a company focused on gene therapy for heart disease. Additionally, they participated in a $6.4 million Series A round for Loop Medical, which is developing innovative medical devices. These investments underscore Casdin Capital's commitment to advancing research and development in the biomedical engineering field.


11. Plug and Play Tech Center


Plug and Play Tech Center is an innovation hub and venture capital firm based in Sunnyvale, California, founded in 2006. They connect startups with corporations to foster growth and innovation, offering various programs including accelerator initiatives and investment opportunities. In 2024, they made 253 investments, showcasing their active role in the venture capital landscape. Notably, they have invested in biomedical engineering companies such as MintNeuro, which raised $1,273,670 in a seed round in November 2024, and AesculaTech, which has received multiple rounds of funding through convertible notes since 2019. These transactions highlight their engagement in the biomedical sector, reinforcing their relevance as an investor in this field.


12. GV (Google Ventures)

  • Website: gv.com
  • Type: Venture Capital
  • Headquarters: San Francisco Bay Area, California, United States (USA)
  • Founded year: 2009
  • Headcount: 51-200
  • Number of deals in 2024: 74
  • LinkedIn: gv

GV (Google Ventures) is a venture capital firm based in the San Francisco Bay Area, founded in 2009, with over $10 billion in assets under management. The firm focuses on various sectors, including life sciences and artificial intelligence, and partners with founders to help them navigate the challenges of building successful companies. Notably, GV has invested in Neuralink, a company developing brain-machine interfaces, and Cala Health, which specializes in neuromodulation therapies. In 2021, GV participated in a $205 million Series C funding round for Neuralink, and in 2024, they invested $50 million in Cala Health's Series C funding round. These transactions highlight GV's active role in the biomedical engineering field, supporting innovative technologies that have the potential to transform healthcare.


13. Polaris Partners

  • Website: polarispartners.com
  • Type: Venture Capital
  • Headquarters: Boston, Massachusetts, United States (USA)
  • Founded year: 1996
  • Headcount: 11-50
  • Number of deals in 2024: 19
  • LinkedIn: polaris-partners

Polaris Partners is a venture capital firm based in Boston, Massachusetts, founded in 1996. The firm specializes in healthcare and biotechnology investments, partnering with entrepreneurs to provide funding and strategic guidance to help them innovate and grow their businesses. Polaris has a diverse portfolio that includes companies focused on transformative healthcare solutions. Notably, they have invested in Arsenal Medical, which has raised significant funding across multiple rounds, including $16 million in 2015 and $13.1 million in 2007, indicating a strong focus on advancing medical technologies. Additionally, they invested $17.5 million in Aspect Medical Systems in 1997, further showcasing their commitment to the biomedical engineering field. Polaris operates primarily in the investment management space, supporting early-stage companies in bringing their products to market.



Biomedical Engineering Insights: Key Investors in the US


InvestorHeadquarterSizeFoundedDeals 2024
MedTech InnovatorLos Angeles, California, United States (USA)11-50201385
Y CombinatorSan Francisco, California, United States (USA)51-2002005802
OrbiMedNew York, New York, United States (USA)51-200198952
SosvUnited States (USA)51-2001995170
Perceptive AdvisorsNew York, New York, United States (USA)11-50199945
New Enterprise Associates (NEA)Menlo Park, California, United States (USA)51-200197757
Deep Tech Fund (an Alumni Ventures Fund)Manchester, New Hampshire, United States (USA)51-2002023258
ARCH Venture PartnersChicago, Illinois, United States (USA)11-50198632
Silicon Valley BankSanta Clara, California, United States (USA)5001-10000198331
Casdin Capital, LLCNew York, New York, United States (USA)11-5020129
Plug and Play Tech CenterSunnyvale, California, United States (USA)501-10002006253
GV (Google Ventures)San Francisco Bay Area, California, United States (USA)51-200200974
Polaris PartnersBoston, Massachusetts, United States (USA)11-50199619


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