The endoscopy device industry in the US is a rapidly growing segment of healthcare that specializes in the development and distribution of minimally invasive diagnostic and therapeutic tools. Companies in this space tend to focus on various specialties, including gastrointestinal, pulmonary, and surgical endoscopy. Recent advancements in technology have spurred innovation, leading to clinically proven devices that offer more effective treatments with reduced recovery times. Notably, the integration of artificial intelligence and robotics promises to enhance procedural accuracy and efficiency, reflecting a trend toward precision medicine that is gaining traction among healthcare professionals.


The group of investors discussed in this article represents a blend of venture capital firms and corporate investors, primarily located in hubs like Silicon Valley and New York City. Founded between 1989 and 2023, these investors have varied sizes, with teams ranging from small boutique firms to larger operations. In 2024 alone, they collectively engaged in 19 to over 800 investment deals, reflecting a robust interest in fostering growth specifically in the endoscopy device sector.


Top 12 Endoscopy Device Investors in the US


1. MedTech Innovator

  • Website: medtechinnovator.org
  • Type: Corporate
  • Headquarters: Los Angeles, California, United States (USA)
  • Founded year: 2013
  • Headcount: 11-50
  • Number of deals in 2024: 85
  • LinkedIn: medtech-innovator

MedTech Innovator is a not-for-profit organization based in Los Angeles, California, founded in 2013. It serves as the largest accelerator for medical technology companies, offering accelerator programs, mentorship, and competitions to support startups in the medical device, digital health, and diagnostics sectors. In recent years, MedTech Innovator has been involved in several transactions relevant to the endoscopy device industry, including supporting companies like Endoluxe, Swift Duct, Lazurite, and EvoEndo through non-equity assistance. Additionally, they participated in the seed round for Pristine Surgical, which focuses on innovative surgical solutions. This involvement highlights their active role in promoting advancements in endoscopy and related medical technologies.


2. Y Combinator

  • Website: ycombinator.com
  • Type: Venture Capital
  • Headquarters: San Francisco, California, United States (USA)
  • Founded year: 2005
  • Headcount: 51-200
  • Number of deals in 2024: 802
  • LinkedIn: y-combinator

Y Combinator is a prominent startup accelerator and venture capital firm based in San Francisco, California, founded in 2005. It provides funding and mentorship to early-stage technology companies through a structured program that includes resources like the Startup School and co-founder matching services. Y Combinator has successfully launched over 4,000 startups, establishing itself as a key player in the technology startup ecosystem. Among its notable investments in the endoscopy device sector are companies like Illuminant Surgical, which raised $500,000 in a Pre-Seed round in 2022, and iSono Health, which raised $120,000 in a Pre-Seed round in 2016. These investments highlight Y Combinator's commitment to supporting innovation in the medical device industry, particularly in endoscopy-related technologies.


3. OrbiMed

  • Website: orbimed.com
  • Type: Venture Capital
  • Headquarters: New York, New York, United States (USA)
  • Founded year: 1989
  • Headcount: 51-200
  • Number of deals in 2024: 52
  • LinkedIn: orbimed-advisors

OrbiMed is a prominent investment firm based in New York, specializing in healthcare investments. Founded in 1989, the firm manages approximately $17 billion in assets across various investment strategies, focusing on biopharmaceuticals, medical devices, and healthcare services. Notably, OrbiMed has participated in significant funding rounds for companies like Aerin Medical, which raised $48 million in 2020 and $60 million in 2022, aimed at scaling commercialization and expanding market access for their medical technologies. Additionally, OrbiMed was involved in funding rounds for ViewRay, a company that develops advanced medical devices, including the MRIdian device, which highlights their engagement in the medical device sector. This diverse portfolio underscores OrbiMed's commitment to driving innovation in healthcare, making them a relevant player in the endoscopy device investment landscape.


4. Sosv

  • Website: sosv.com
  • Type: Venture Capital
  • Headquarters: United States (USA)
  • Founded year: 1995
  • Headcount: 51-200
  • Number of deals in 2024: 170
  • LinkedIn: sosv

SOSV is a venture capital firm founded in 1995, specializing in funding and supporting deep tech startups through its development programs. With a global reach, SOSV connects innovative companies with investors, providing not only venture capital investment but also resources to help startups grow and succeed. In recent transactions, SOSV participated in funding rounds for Leadoptik, a Silicon Valley-based medical imaging company, which raised $5 million in a series seed funding round to advance its product development and seek FDA approval. Additionally, SOSV has been involved in funding Ostoform, which focuses on medical solutions, further showcasing their commitment to the health technology sector. These transactions highlight SOSV's active role in the medical technology landscape, making them a relevant player in the endoscopy device industry.


5. New Enterprise Associates (NEA)

  • Website: nea.com
  • Type: Venture Capital
  • Headquarters: Menlo Park, California, United States (USA)
  • Founded year: 1977
  • Headcount: 51-200
  • Number of deals in 2024: 57
  • LinkedIn: new-enterprise-associates

New Enterprise Associates (NEA) is a prominent venture capital firm based in Menlo Park, California, founded in 1977. NEA specializes in investment management and advisory services for startups, particularly in the technology and healthcare sectors. The firm partners with entrepreneurs to provide funding and strategic guidance, helping them navigate the challenges of building successful businesses. NEA operates through a collaborative approach, emphasizing long-term relationships with founders. Notably, NEA has been involved in significant transactions within the healthcare space, including investments in Minerva Surgical, which focuses on surgical devices, and Cartiva, which has developed medical technologies. Their investment in Minerva Surgical in 2022 and previous rounds for Cartiva demonstrate their commitment to supporting innovations in medical devices, including those relevant to endoscopy procedures.


6. Perceptive Advisors


Perceptive Advisors is a New York-based venture capital firm founded in 1999, specializing in the life sciences sector. The firm provides capital solutions and investment management services to both private and public healthcare companies, with a strong focus on biotechnology, pharmaceuticals, and medical devices. Notably, Perceptive Advisors has been involved in significant transactions within the endoscopy device context, such as their investment in Motus GI, which raised $30 million in a venture round aimed at advancing endoscopic technologies. Additionally, they participated in funding rounds for PROCEPT BioRobotics, which is known for its AquaBeam Robotic System, a technology that enhances surgical procedures related to endoscopy. Their involvement in these companies highlights their commitment to supporting innovation and growth in the endoscopy device industry.


7. Deep Tech Fund (an Alumni Ventures Fund)

  • Website: av.vc
  • Type: Venture Capital
  • Headquarters: Manchester, New Hampshire, United States (USA)
  • Founded year: 2023
  • Headcount: 51-200
  • Number of deals in 2024: 258
  • LinkedIn: deep-tech-fund-av-focused-fund

Deep Tech Fund (an Alumni Ventures Fund) is a venture capital firm founded in 2023, based in Manchester, New Hampshire. The fund is part of Alumni Ventures, which connects accredited investors with high-quality investment opportunities in the startup ecosystem. With a network of over 10,000 investors, the fund focuses on diversified venture portfolios. Notably, the fund has participated in significant healthtech transactions, including Iterative Scopes, which raised $150 million to enhance computational technologies for gastroenterology care, and Innoblative Designs, which is involved in innovative medical device solutions. These investments highlight the fund's engagement in sectors that align with endoscopy and related medical technologies.


8. Plug and Play Tech Center


Plug and Play Tech Center is an innovation hub and venture capital firm based in Sunnyvale, California, founded in 2006. They connect startups with corporations to foster growth and innovation, offering various programs including accelerator initiatives and investment opportunities. In 2024, they have made 253 investments, showcasing their active role in the venture capital landscape. Notably, they have invested in companies like Iterative Scopes, which focuses on gastrointestinal health, and MediView XR, a medical device company that has raised $4.5M in seed funding. These transactions highlight their engagement in the medical device sector, particularly in areas that could intersect with endoscopy technology.


9. Silicon Valley Bank

  • Website: svb.com
  • Type: Venture Capital
  • Headquarters: Santa Clara, California, United States (USA)
  • Founded year: 1983
  • Headcount: 5001-10000
  • Number of deals in 2024: 31
  • LinkedIn: silicon-valley-bank

Silicon Valley Bank is a commercial bank founded in 1983, located in Santa Clara, California, that specializes in providing financial services to the innovation economy, particularly tech startups and venture capital firms. They offer a range of products including business banking, global payments, and asset management, helping clients navigate financial challenges and support their growth. Notably, Silicon Valley Bank has been involved in several transactions within the medical device sector, including Motus GI, which raised $8 million in post-IPO debt, and Palette Life Sciences, which raised $40 million in debt financing. These transactions highlight their active role in supporting companies that are relevant to the endoscopy device industry, further solidifying their position as a potential investor in this space.


10. Polaris Partners

  • Website: polarispartners.com
  • Type: Venture Capital
  • Headquarters: Boston, Massachusetts, United States (USA)
  • Founded year: 1996
  • Headcount: 11-50
  • Number of deals in 2024: 19
  • LinkedIn: polaris-partners

Polaris Partners is a venture capital firm based in Boston, Massachusetts, founded in 1996. The firm specializes in healthcare and biotechnology investments, partnering with entrepreneurs to provide funding and strategic guidance to help them innovate and grow their businesses. Polaris has a diverse portfolio that includes companies focused on transformative healthcare solutions. Notably, they have invested in GI Dynamics, which is developing the EndoBarrier, a device aimed at treating type 2 diabetes and obesity through endoscopic means. They also invested in BridgePoint Medical, which focuses on innovative medical devices. These transactions highlight Polaris Partners' commitment to advancing technologies in the endoscopy device space, making them a significant player in this industry.


11. F-Prime


F-Prime Capital is a venture capital firm based in Cambridge, Massachusetts, founded in 1946. The firm specializes in creating and investing in healthcare and technology companies, providing both venture capital investments and advisory services to entrepreneurs. F-Prime has a global presence and expertise that enables them to effectively support startups in developing innovative solutions. Notably, F-Prime has been involved in several funding rounds for ViewRay, a medical device company that focuses on advanced imaging technology for radiation therapy. Their investments in ViewRay include a $45 million Series C round in 2012, a $20 million Series C equity offering in 2010, and additional funding rounds in 2011 and 2013. Although ViewRay's primary focus is not on endoscopy devices, their technology is relevant to the medical device field, indicating F-Prime's engagement in sectors that could intersect with endoscopic innovations.


12. Khosla Ventures

  • Website: khoslaventures.com
  • Type: Venture Capital
  • Headquarters: Menlo Park, California, United States (USA)
  • Founded year: 2004
  • Headcount: 51-200
  • Number of deals in 2024: 97
  • LinkedIn: khosla-ventures

Khosla Ventures is a venture capital firm founded in 2004, based in Menlo Park, California. The firm specializes in providing funding and strategic guidance to startups across various sectors, including technology, healthcare, and sustainability. Notably, Khosla Ventures has invested in companies like Vicarious Surgical, which raised substantial funding in multiple rounds, including a $142 million post-IPO equity round in 2021 and several series A rounds totaling over $22 million. Additionally, they have invested in Docbot, which focuses on surgical automation and has raised funds in both seed and series A rounds. These investments highlight Khosla Ventures' active role in the healthcare technology landscape, particularly in areas relevant to endoscopy devices.



Endoscopy Device Insights: Key Investors in the US


InvestorHeadquarterSizeFoundedDeals 2024
MedTech InnovatorLos Angeles, California, United States (USA)11-50201385
Y CombinatorSan Francisco, California, United States (USA)51-2002005802
OrbiMedNew York, New York, United States (USA)51-200198952
SosvUnited States (USA)51-2001995170
New Enterprise Associates (NEA)Menlo Park, California, United States (USA)51-200197757
Perceptive AdvisorsNew York, New York, United States (USA)11-50199945
Deep Tech Fund (an Alumni Ventures Fund)Manchester, New Hampshire, United States (USA)51-2002023258
Plug and Play Tech CenterSunnyvale, California, United States (USA)501-10002006253
Silicon Valley BankSanta Clara, California, United States (USA)5001-10000198331
Polaris PartnersBoston, Massachusetts, United States (USA)11-50199619
F-PrimeCambridge, Massachusetts, United States (USA)11-50194639
Khosla VenturesMenlo Park, California, United States (USA)51-200200497


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